Abstract: Generally discussed herein are systems, devices, and methods for providing a therapy (e.g., stimulation) and/or data signal using an implantable device. Systems, devices and methods for interacting with (e.g., communicating with, receiving power from) an external device are also provided.

Abstract: Provided is a biosensor device including: a signal generating unit for generating a continuous wave signal; an antenna for emitting the continuous wave signal as a radio wave; a variable matching circuit for performing impedance matching between the signal generating unit and the antenna; a detection circuit for outputting a detection signal on the basis of the continuous wave signal generated by the signal generating unit and a reflected signal of a radio wave incident on the antenna; and a control unit for controlling an element value of the variable matching circuit from the detection signal in a predetermined period corresponding to one cycle or more time in which heartbeat and respiration waveforms can be measured on the basis of the detection signal.

Abstract: Provided herein as a transoral minimally invasive method and a system thereof for the treatment of gastrointestinal diseases and/or obesity, which at least partially encircles a part of the gastrointestinal tract, such as esophagus of the patient by advancing an elongated deformable portion of a neurostimulator assembly endoluminally to the subfascial area from the outer wall of the esophagus and introducing the elongated deformable portion sub-fascially in the subfascial area, whereby at least one part of the encircled esophagus will be modulated using a modulator.

Abstract: An implantable medical device includes an enclosure sleeve and a top cap. The enclosure sleeve comprises an enclosure wall with at least a portion of the enclosure wall comprising the grade 5 titanium and having a thickness between 0.007 inches and 0.009 inches. The enclosure sleeve includes an open top end and an open bottom end that is opposite the open top end. The top cap includes a feedthrough block, a first top cap end portion, and a second top cap end portion. The first top cap end portion is configured to couple to the open top end of the enclosure sleeve, and the second top cap end portion configured to be positioned within the enclosure sleeve.

Abstract: A neurovascular coupling analytical method based on an electroencephalogram and functional near-infrared spectroscopy includes: S100: acquiring an electroencephalogram signal and a brain hemodynamic signal; S110: extracting an event-related potential signal from the electroencephalogram signal; S120: extracting a time characteristic from the event-related potential signal; S130: extracting a hemodynamic response function from the brain hemodynamic signal; S140: extracting an amplitude characteristic and time characteristics from the hemodynamic response function; and S150: analyzing influence of the time characteristic of the event-related potential signal on the amplitude characteristic and the time characteristics of the hemodynamic response function to obtain a coupling result. The time characteristic of the event-related potential signal is a delay.

Abstract: A meridian stimulation device according to the present specification may comprise: a power supply unit that supplies power; a detection unit that detects the cardiac cycle of a user while attached to the skin of the user; at least one pad attached to a predetermined position on the user and including a light emitting unit that emits visible light, and a filter through which the visible light is transmitted; and a control unit that controls the operation of the light emitting unit on the basis of the cardiac cycle of the user.

Abstract: A surgical end effector assembly includes first and second jaw members configured to grasp tissue. Each of the first and second jaw members includes a proximal flange portion and a distal body portion. The proximal flange portions are pivotably coupled to one another to move the distal body portions between a spaced-apart position and an approximated position.

Abstract: Apparatus for tissue treatment includes a central blunt urethra fixator, which may serve as a return electrode. An array of electrodes is positioned circumferentially about the central blunt urethra fixator and distanced radially from the central blunt urethra fixator. At least one of the electrodes is an active electrode. The central blunt urethra fixator and electrodes protrude from a housing. A main unit includes an RF generator, a controller unit, a power supply and a user interface. The main unit delivers RF energy between the return electrode and a conductive tip of the active electrode to create collagen contraction in a vicinity of the active electrode.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that may include a connector port subassembly. The connector port subassembly may include one or more connector blocks configured to interference fit within a connector bore, one or more windows through the core subassembly to the one or more connector blocks, and one or more seal rings configured to interference fit within the connector bore and eliminate adulterant entry into the connector bore through the one or more windows.

Abstract: An electrocardiogram (ECG) measurement device for a vehicle is provided. The ECG measurement device includes an impedance compensator that corresponds to an electrode in contact with a body of a driver and configured to compensate an impedance of each of electrode signals received from the electrode. An electrode selector sequentially selects the electrode signals in response to receiving the electrode signals from the electrode. A differential amplifier differentially amplifies the electrode signals. In particular, each electrode signal has the compensated impedance. Additionally, a signal quality evaluator evaluates quality of an ECG signal output from the differential amplifier and a compensation controller then adjusts an impedance compensation value of each of the impedance compensators as a result of evaluating the quality of the ECG signal.

Abstract: Systems and methods for heart stimulation in accordance with embodiments of the invention are illustrated.

Abstract: The present invention provides devices and methods that can prevent or ameliorate bronchoconstriction by stimulating neural activity, in contrast to those techniques based on denervation, ablation or blocking of neural activity. Methods and devices according to the invention may act responsively or on demand, can preserve neuronal structure and function and will be associated with minimal collateral side-effects. In particular, the invention provides devices and methods in which a signal is delivered to the vagus nerve, for example the cervical vagus nerve or the pulmonary branch of the vagus nerve, in order to stimulate neural activity in the vagal nerve.

Abstract: Presented herein are techniques for generating a stable reference clock for use by a short-range radio transceiver of an implantable component without the need for an X-tal oscillator within the implantable component itself. In accordance with certain techniques presented herein, the implantable component is in communication with a first external component via a closely-coupled link and in communication with a second external component via short-range radio link. The implantable component is configured to receive, from the first external component, signals via the closely-coupled link. The implantable component is configured to extract frequency information from these received signals and synchronize a carrier frequency of the short-range radio link to the frequency information extracted from the signals.

Abstract: Some embodiments of the current disclosure are directed toward physiological monitoring of patients, and more particularly, systems, devices and methods for physiological monitoring of patients with a continuous or near-continuous transmission and analysis of monitored physiological data during the monitoring process. In some embodiments, a physiological patient monitoring system is provided which includes a physiological monitoring device which comprises a housing disposed on a patch, and the patch is configured for removable attachment to or proximate the skin of a patient, the housing including at least one memory. Antenna disposed on the housing transmit radio-frequency (RF) waves towards a targeted portion of an internal tissue of the patient and receive reflected RF waves from the internal tissue. RF circuitry in communication with the at least one memory perform an RF-based measurement of a lung fluid level of the patient during a predetermined time period.

Abstract: The invention discloses an electrochemical device for treating cancer, characterized by using an acupuncture needle as a working electrode to produce hydrogen in a tumor tissue, thereby destroying the tumor tissue through the produced hydrogen gas. The device of the invention has low cost and simple operation, can realize minimally invasive treatment, and is green and environmentally friendly.

Abstract: Disclosed is a flexible surgical instrument system, comprising a flexible continuum structure consisting of a distal structure, a middle connecting body and a proximal structure linked in sequence, and further comprising a transmission driving unit linked to the proximal structure. The transmission driving unit comprises a plurality of transmission mechanisms respectively driving corresponding proximal segments. The transmission mechanisms are operable to control the direction of a bending plane of the proximal segments and to control the bending angle of the proximal segments in the bending plane, so as to drive the proximal segments in the proximal structure to bend or turn in any arbitrary direction, and to further drive distal segments in the distal structure linked thereto to bend or turn in the opposite direction.

Abstract: An apparatus is disclosed for determining validity of a measured in-blood percentage of oxygenated hemoglobin. The apparatus has multiple pulse oximetry channels having at least three light sources of at least three distinct wavelengths, which are detected and converted to digital signals. The light sources are selectively activated, and two or more estimated in-blood percentages of oxygenated hemoglobin are calculated. It is determined whether a signal quality associated with the calculated in-blood percentages exceeds a predetermined accuracy threshold, and an associated validity indication is provided.

Abstract: A method for optimization of the stimulation pattern of a set of implanted electrodes in excitable tissue of a patient is disclosed, wherein it comprises the steps of: (a) choosing a first group of a certain number of from said set of implanted electrodes, (b) stimulating the excitable tissue electrically by said first group of electrodes, (c) registering information provided by the patient, (d) assigning each electrode of said first group of electrodes a value related to said information, wherein these steps are repeated for one or more further groups of said certain number of electrodes chosen from said set of implanted electrodes, wherein each electrode may be included in one or several groups, wherein the total assigned value for each electrode is calculated, and wherein electrodes having a total assigned value exceeding a predetermined value or a predetermined number of the electrodes having the highest total assigned value are chosen to be included in said stimulation pattern, as well as a method for tr

Abstract: A sheath assembly for the insertion of a percutaneous pump includes a tubular sheath body dimensioned for insertion into a blood vessel through a vessel aperture. The tubular sheath body includes a wall having a proximal end portion, a distal end portion, a longitudinal axis, an outer surface, an inner surface defining a first lumen substantially parallel to the longitudinal axis, and a second lumen disposed within the wall between the inner surface and the outer surface and extending from the proximal end portion to the distal end portion. The first lumen is dimensioned to allow passage of a portion of the percutaneous pump, and the second lumen is dimensioned for passage of a guidewire. A stylet is removably positioned to substantially occlude the second lumen. The stylet has a proximal end releasably secured to the sheath assembly.

Abstract: Limited-number-of-use neuromodulator apparatuses that may be comfortably worn on the skin of a user to non-invasively apply transdermal electrical stimulation (TES). The apparatuses described herein may be include a flexible/bendable substrate and an elastomeric cover (e.g., formed of an elastomeric fabric). These apparatuses may be simplified, to run autonomously. These apparatuses may also include improved power management features.