Abstract: A medical device delivers a therapy to a patient. The medical device or another device may periodically determine an activity level or gait parameter of the patient, and associate each determined level or parameter with a current therapy parameter set. A value of at least one activity metric is determined for each of a plurality of therapy parameter sets based on the activity levels or parameters associated with that therapy parameter set. Whether the patient is currently experiencing or anticipated to experience gait freeze caused by their neurological disorder, such as Parkinson's disease, may also be determined. Gait freeze events may be associated with current therapy parameters and used to determine activity metric values. In some examples, the activity metric associated with certain therapy parameters may be presented to a user.

Abstract: Transcutaneous electrical and magnetic nerve stimulation devices are disclosed, along with methods of averting imminent medical attacks using energy that is delivered noninvasively by the devices. The attacks comprise asthma attack, epileptic seizure, attacks of migraine headache, transient ischemic attack or stroke, onset of atrial fibrillation, myocardial infarction, onset of ventricular fibrillation or tachycardia, panic attack, and attacks of acute depression. The imminence of an attack is forecasted using grey-box or black-box models as used in control theory. A vagus nerve in the neck of a patient can be stimulated noninvasively to avert the attack.

Abstract: A modular header and method of fabricating same for making electrical connection between an array of feed-through pins extending through a wall of a hermetically sealed enclosure of an implantable medical device and lead connect or receptacles within the header in which the header is fabricated using a pre-formed molded header module, together with a set or harness of interconnected flexible conductors incorporated and sealed by an overlayer of medical grade polymer material. The assembled modular header is capable of complete pre-testing prior to assembly onto an implantable medical device.

Abstract: In a catheter (2) to assist the performance of a heart (1) with at least one pump (7), the pump is formed as a rotary pump at the distal end of the catheter (2), the rotor (6) lying distally on the outer side being coupled via a magneto coupling with a drive wheel (21), formed as a hydraulically or pneumatically operated paddle wheel, arranged inside the catheter (2). The driving fluid is supplied to the paddle wheel via a lumen (22) of the catheter (2) and is carried off via a further lumen (23) of the catheter.

Abstract: Devices and methods obtain and use endovascular electrograms in a number of clinical applications and settings. In one embodiment, methods for triggering analysis of an endovascular ECG waveform are based on the detection of a peak in a skin-based ECG waveform in order to determine a location of an indwelling medical device, such as a catheter. In another embodiment, the position of a catheter or other medical device within the vasculature can be determined by analysis of the energy profile of a detected P-wave. In yet other embodiments, magnetic connecting devices are used for establishing an operable connection through a sterile field.

Abstract: An animal monitoring device configured as a bolus for oral administration to reside in the reticulorumen of a ruminant animal. The animal monitoring device includes a memory element, a processor in communication with the memory element and a computer code contained in the memory element. The computer code includes a power management module executable by the processor to regulate power use by the bolus based on determination of remaining energy stored in an energy source and the determined power requirements over a pre-determined life cycle of the bolus.

Abstract: A method that electrically stimulates a heart muscle to alter the ejection profile of the heart, to control the mechanical function of the heart and reduce the observed blood pressure of the patient. The therapy may be invoked by an implantable blood pressure sensor associated with a pacemaker like device. In some cases, where a measured pretreatment blood pressure exceeds a treatment threshold, a patient's heart may be stimulated with an electrical stimulus timed relative to the patient's cardiac ejection cycle. This is done to cause dyssynchrony between at least two cardiac chambers or within a cardiac chamber, which alters the patient's cardiac ejection profile from a pretreatment cardiac ejection profile. This has the effect of reducing the patient's blood pressure from the measured pretreatment blood pressure.

Abstract: Transcutaneous electrical and magnetic nerve stimulation devices and methods of treating lower urinary tract disorders deliver energy noninvasively to nerves within a patient. The disorders comprise overactive bladder, urge incontinence, stress incontinence, urge frequency, non-obstructive urinary retention and interstitial cystitis/painful bladder syndrome. For example, a posterior tibial nerve of a patient is stimulated non-invasively. Protocol parameters are selected for a nerve stimulation session for treating each individual patient, where modules of the bladder of the patient are represented as coupled non-linear oscillators.

Abstract: Systems, devices and methods for averting imminent medical attacks comprise transcutaneous electrical and magnetic nerve stimulation devices using energy that is delivered non-invasively to the patient. One or more sensors detect physiological and/or environmental signals within a patient and the values of these signals are used to forecast an acute medical event, which can be treated via non-invasive nerve stimulation. The acute medical events may comprise, among others, bronchoconstriction, epileptic seizures, primary headache, such as migraine or cluster headaches, transient ischemic attack or stroke, onset of atrial fibrillation, myocardial infarction, and acute depression or anxiety.

Abstract: An example system includes a stimulation generator configured to deliver electrical stimulation therapy to tissue of a patient in accordance with a stimulation therapy program. The stimulation therapy program may include a set of stimulation therapy parameters. The system may include at least one sensor configured to detect a signal including an evoked compound muscle action potential (eCMAP) in response to the application of stimulation according to the stimulation therapy program. The system may also include a processor configured to adjust one or more or the stimulation therapy parameters based on the detected signal that includes the eCMAP.

Abstract: In at least one example, a medical device is provided. The medical device includes at least one therapy electrode, at least one acoustic sensor, and at least one processor coupled with the at least one therapy electrode and the at least one acoustic sensor. The at least one processor is configured to deliver at least one pacing pulse via the at least one therapy electrode and to analyze processed acoustic data to determine whether the at least one pacing pulse resulted in capture.

Abstract: A bracket including a main body part and a covering part. The main body part includes a first surface portion and a first bottom face portion. The first surface portion is provided with a first groove, which divides the first surface portion into first and second ends. The first end has a surface with a first protruding portion having a smooth curved surface. The covering part includes a second surface portion and a second bottom face portion, the second bottom face portion matches with the surface of the second end, and the second surface portion has a smooth curved surface matching the surface of the first protruding portion. The covering part and the main body part are adapted to match and be engaged with each other to form the bracket having a smooth curved shape in a gingival direction, an occlusal direction, a mesial direction and a distal direction.

Abstract: An operating room cable assembly for electrically coupling at least one implantable electrical stimulation lead to a trial stimulator includes an elongated body; a trial stimulator connector disposed at one end of the elongated body; and a lead connector disposed at another end of the elongated body. The lead connector can include one or more buttons that can be pushed to load a lead into the lead connector and released to retain the lead. Alternatively, the lead connector can include a lever that can be operated to load the lead. A further alternative is a slider with a lead engagement element that can be slid between positions allowing loading of a lead and engagement of the lead. Other alternatives include a lead connector with doors that can swing open to allow loading of a lead or a collet/sleeve that can be tightened on the lead.

Abstract: Methods, devices, and systems induce neuromodulation by focusing a source of stimulation through a skull/brain interface in the form of an aperture formed in the skull, a naturally occurring fenestration in the skull, or a transcranial channel. Methods, devices, and systems identify where to locate skull/brain interfaces, accessories that can be used with the interfaces, and features for controlling stimulation delivered through the interfaces. Multiple indications for the skull/brain interfaces include diagnosis and treatment of neurological disorders and conditions such as epilepsy, movement disorders, depression, Alzheimer's disease, autism, coma, and pain.

Abstract: The present invention is a flexible circuit electrode array with a polymer base layer, metal traces deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue, a polymer top layer deposited on the polymer base layer and the metal traces, and a soft polymer filling a void through both the polymer base layer and polymer top layer, the soft polymer forming drum stress relief around an attachment point.

Abstract: A method and system of providing therapy to a patient's uterus is provided, which can include any number of features. The method can include the steps of inserting a uterine device into the uterus and performing a uterine integrity test to determine that the uterus is intact and not perforated. If it is determined that the uterus is not perforated, a patency test can be performed to determine that the uterine device is not clogged or embedded in tissue. If the uterus is intact and the device is not clogged or embedded in tissue, the uterus can be treated with the uterine device, e.g., uterine ablation. Systems for performing these methods are also disclosed.

Abstract: A medical lead screening connector includes a housing, a plurality of electrical contacts disposed within the housing, where each lead receptor channel includes at least two lead receptor contacts, and a cover hingedly attached to the housing. The cover includes a protrusion that is arranged and configured to register with one of the lead receptor channels and contacts a lead body received in the lead receptor channel when the cover is in a closed position.

Abstract: An apparatus, a system and methods for modulating and monitoring tissue have an elongate member with proximal and distal ends and a plurality of annular stimulating electrodes axially arranged along the elongate member. The stimulating electrodes are disposed near the distal end and are adapted to pass current into tissue. At least one of the annular stimulating electrodes has at least three independent stimulation points on the electrode. The apparatus also includes a plurality of recording electrodes that are adapted to measure local tissue potentials and a plurality of conductors are coupled with the recording and stimulating electrodes. An optional multiple contact connecting terminal may be coupled with the conductors and is disposed near the proximal end of the elongate member.

Abstract: A system and method of network-enabled automatic electronic defibrillators (AEDs) may be used to assist with cardiac emergencies. The system includes at least two AEDs positioned in different geographic locations. At least one location-providing tag is positioned on each of the at least two AEDs. A controller is capable of communicating with the location-providing tag of each of the at least two AEDs through at least one network connection. When a cardiac emergency occurs, an AED located nearby may be identified or requested to assist with the emergency.

Abstract: Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Also disclosed are various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.