Abstract: This invention is directed to benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Type:
Grant
Filed:
November 12, 1999
Date of Patent:
May 15, 2001
Assignee:
Berlex Laboratories, Inc.
Inventors:
Monica Kochanny, Michael M. Morrissey, Howard P. Ng