Patents Examined by Tamthom N. Truona
  • Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade
    Patent number: 6458952
    Abstract: The invention relates to substituted polycyclic aryl and heteroaryl uracil compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: October 1, 2002
    Assignee: Pharmacia Corporation
    Inventors: Michael South, Darin E. Jones, Melvin L. Rueppel