Abstract: A dressing for treating a tissue site with negative pressure may comprise a cover having an adhesive, a manifold, a perforated polymer film, and a perforated silicone gel having a treatment aperture. The cover, the manifold, the perforated polymer film, and the perforated silicone gel may be assembled in a stacked relationship with the cover and the perforated silicone gel enclosing the manifold. The perforated polymer film may be at least partially exposed through the treatment aperture, and at least some of the adhesive may be exposed through the perforated silicone around the treatment aperture.

Abstract: A base plate for an ostomy appliance, the base plate (4) comprises a top layer (208) defining a base plate plane; a first adhesive layer (200) adapted to adhere the base plate (4) to peristomal skin of a user; an electrode assembly (204); and a monitor interface (207) configured to electronically connect with the electrode assembly (204), where the monitor interface (207) comprises a coupling part (210) configured to form a releasably mechanically and/or electronically coupling between the base plate (4) and a monitor device (6); the coupling part (210) is configured to engage and/or disengage with the monitor device (6) allowing the monitor device (6) to be coupled to the base plate by a motion in a direction corresponding to an acute angle of 45 degrees or less relative to the base plate plane.

Abstract: An exemplary apparatus, can include, for example, a circulating tumor cell (CTC) treatment arrangement, a pump arrangement configured to circulate a fluid through the CTC treatment arrangement, and an electric field generator electrically connected to the CTC treatment arrangement, and configured to apply an electric field to the fluid circulating through the CTC treatment arrangement. The pump arrangement can be a peristaltic pump, which can be configured to continuously circulate the fluid through the CTC treatment arrangement. According to another exemplary embodiment of the present disclosure, method, system and computer-accessible medium can be provided for killing at least one circulating tumor cell (CTC). Using such exemplary embodiment, blood can be pumped from a body of a patient to an electroporation chamber inside of a CTC treatment arrangement. An electric field can be applied to the blood located in the electroporation chamber in order to kill the CTC.

Abstract: Connectors and devices for flexible negative pressure systems are described.

Abstract: An article including a front region, a back region, and a chassis. The chassis may include an absorbent core having a front end edge and a back end edge. The front region and the back region may extend laterally outward beyond side edges of the chassis. The front region and the back region may abut to form a first seam and a second seam. At least one of the front region and the back region may include an elastic member. A first outer nonwoven layer of the front region and a second outer nonwoven layer of the back region may be folded to form an upper edge in the front and back regions such that a distal end of each of the first and second outer nonwoven layer may be disposed between the upper edge and the front and back end edges of the absorbent core, respectively.

Abstract: The utility model discloses a urinary catheter for women and peristaltic pump, which comprises a body tube with an inner surface and an outer surface, and further comprises an external urethral orifice fixing part which can at least sleeve the catheter tip end inside when applied, a flexible urethral guide part, a urinary catheter driving part sleeved with the cylindrical body of the external urethral orifice fixing part, a hydrophobic part for leakage stop at the urinary outlet of the urinary catheter, a thin segment, a pump tube, a tube bed and other special structures for dilating the narrowed part of the urethra, which not only eliminate the defect of the traditional “non-guided suspended placement” in a safe mode of “US-guided adjacent placement” and completely avoid contamination of the urinary catheter by the periurethral tissue, but also avoid the injury of urethral intima caused by urethral stricture in the placement procedure to the greatest extent; avoid contamination of the urinary catheter outlet

Abstract: The invention relates to a unit for hemostasis. The unit is configured to be directly applied to a bleeding wound and comprises an envelope enclosing an inner space as well as an effective amount of a hemostatic material disposed within the inner space. Furthermore, the invention relates to an arrangement of two or more such units for hemostasis, the units being coupled to each other. Moreover, the invention relates to a method for producing an arrangement of units for hemostasis. In accordance with the method, an effective amount of a hemostatic material is disposed within an interior region of a starting material, and neck regions are formed on both sides of the charge so as to form an envelope enclosing the charge.

Abstract: An ostomy pouch includes an outer wall (12) having an inlet opening (24) and a filter (20), the outer wall defining an interior volume (14), an internal wall structure (16) disposed within the interior volume, a one-way valve (22) connected to the internal wall structure, and a path (18) formed by the internal wall structure, the path having an opening (28) at one end and the one-way valve at another end, wherein the filter is positioned within the path.

Abstract: The present invention relates to a method of adding an anticoagulant to the blood of a patient, wherein the addition takes place in the form of a bolus, wherein the bolus application time B depends on the values TBV and CO, with TBV representing the blood volume of the patient and CO the cardiac output of the patient. The present invention furthermore relates to an apparatus for adding a coagulant to the blood of a patient.

Abstract: The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Preferred embodiments can utilize tissue grasping elements to apply a wound closing force to the tissue.

Abstract: In some embodiments, a negative pressure apparatus includes a negative pressure source configured to provide negative pressure via a fluid flow path to a wound dressing placed to create a seal over a wound, a pressure sensor, and a controller. The controller can be configured to operate the negative pressure source in a first mode and determine a change in pressure in the fluid flow path over a period of time based on a plurality of measurements by the pressure sensor. In response to a determination that pressure in the fluid flow path is decreasing, the controller can operate the negative pressure source in a second mode in which greater amount of negative pressure is provided than in the first mode. In response to a determination that pressure in the fluid flow path is not decreasing, the controller can provide an indication of a first leak in the seal.

Abstract: A method of producing an arteriovenous (AV) fistula includes producing an anastomosis between a primary blood vessel (e.g., a vein) and a secondary blood vessel (e.g., an artery). A collateral (or competing) blood vessel in fluid communication with one of the primary blood vessel or the secondary blood vessel is identified. A reversible flow restrictor is then applied to the collateral blood vessel to reduce a blood flow rate through the collateral blood vessel. In some embodiments, the anastomosis can be produced percutaneously. In some embodiments, the reversible flow restriction (or a portion thereof) can be removed from the collateral blood vessel. In other embodiments, the reversible flow restriction (or a portion thereof) can be adjusted to allow increased blood flow therethrough while within the collateral blood vessel.

Abstract: A wound monitoring and/or therapy system can include a substantially stretchable substrate supporting a plurality of electronic components, including sensors, and a plurality of electronic connections that connect at least some of the electronic components. The electronic components can also include a circuit board supporting at least one controller configured to control at least some of the sensors, the circuit board configured to operate without failure when the substrate is flexed as a result of strain. A calibration track can be positioned on the substrate and connected to a monitoring circuit configured to measure a change in resistance of the calibration track indicative of resistance change of at least some of the plurality of electronic connections. The system can include a controller with a circuit board supporting a plurality of electrical components and an antenna configured to communicate with the substrate, the antenna at least partially enclosing the circuit board.

Abstract: An adhesive ostomy wafer includes a first adhesive, a skin-facing adhesive located proximal of the first adhesive, and a neutralizer located in an envelope that is contained by the first adhesive and the skin-facing adhesive. The adhesive ostomy wafer includes a stoma-receiving hole formed through wafer such that the first adhesive, the neutralizer, and the skin-facing adhesive are exposed within the stoma-receiving hole.

Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.

Abstract: A urinary collection receptacle (10,50,650) with a handle seal (22,52,654) defining a handle opening is provided with one or more tear-controlling features to prevent a user from tearing through the handle seal when creating a spout to empty urine. The receptacle is be configured to require a user to create a generally linear tear (30) that extends from one edge (16) of the bag to the opposite edge (18) without passing through the handle seal. Alternatively a tear-stopping formation (62) is positioned adjacent to the handle seal to terminate a fear propagating toward the handle seal. Alternatively, a tear-starting formation (652) is positioned adjacent to the handle seal to direct a tear away from the handle seal. Such a receptacle further includes a frangible region that can be broken to dissociate a torn portion of the receptacle from the remainder of the receptacle.

Abstract: The disclosed is an ostomy system configured to detect a leakage of output between a base plate and/or a sensor assembly part of the ostomy system and a surface of a subject and a method of detecting the leakage of output.

Abstract: A complementary-material element configured to be attachable to a base plate of an ostomy appliance and comprising a release layer, the element comprising a release layer comprises a neutralizing component configured to be releasable from the complementary-material element in response to subjection of the complementary-material element to moisture. The complementary-material element comprises a first surface and a second surface, wherein the first surface is provided with a first cover layer.

Abstract: An evacuation system and method for removing and/or treating gaseous and/or particulate byproducts of surgical procedures includes an end effector such as a side vent trocar, an operating room tower or the equivalent, a disposal vessel, a vacuum source and optionally a filter. The end effector may be coupled to the tower by a conduit, the tower may be coupled to the collection tank by a conduit, and the collection tank may be coupled to the vacuum source. Gaseous and/or particulate byproducts may flow from the surgical site through the trocar, conduits, tower tank and filter, and the flow may be regulated at least in part by the components of the system.

Abstract: A closed-system urinary catheter with a low viscosity gel lubrication is disclosed. The system has an uncoated catheter, but a hydrophilic coated catheter could be used. The low viscosity lubricating gel within the sachet uniformly coats the catheter when the sachet is ruptured just prior to use. A low viscosity lubrication gel could alternatively be place in the area inside the sheath and external to the catheter. Therefore, the variability that occurs with a hydrophilic catheter or the areas of a non-lubricated catheter with the higher viscosity gel catheters is avoided.