Abstract: This invention relates to an isolated nucleic acid fragment encoding a methionine metabolic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the methionine metabolic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the methionine metabolic enzyme in a transformed host cell.

Abstract: The present invention is directed to nucleic acids encoding vespid venom phospholipases, or fragments thereof, recombinant vectors comprising such nucleic acids, and host cells containing the recombinant vectors. The invention is further directed to expression of such nucleic acids to produce recombinant vespid venom phospholipases, or recombinant fragments, derivatives or analogs thereof. Such recombinant products are useful for diagnosis of allergy and for therapeutic treatment of allergy. In specific embodiments, the present invention provides nucleic acids encoding, and complete nucleotide and amino acids sequences for, vespid venom phospholipase A1, for example, Dolichovespula maculata phospholipase A1 and Vespula vulgaris phospholipase A1.