Patents Examined by Terapane
  • Halocyclopropyl substituted phenoxyalkanoic acids
    Patent number: 3948973
    Abstract: Halocyclopropyl substituted phenoxyalkanoic acids and esters thereof, having hypocholesteremic activity are prepared via several alternative synthetic approaches, involving as the key reactions interaction of a substituted phenylalkene with a carbene source to introduce the halocyclopropyl moiety, and reaction of a substituted phenol with chloroform and a lower-alkanone in the presence of base, or with a lower-alkyl .alpha.-bromo-alkanoate, to form the phenoxyalkanoic acid moiety.
    Type: Grant
    Filed: February 19, 1974
    Date of Patent: April 6, 1976
    Assignee: Sterling Drug Inc.
    Inventor: Donald K. Phillips