Abstract: The present invention relates to methods and compositions utilizing inteins to generate libraries of cyclic peptides in vivo. The prevent invention also relates to methods for inhibiting protein-protein interaction.
Type:
Grant
Filed:
February 28, 2005
Date of Patent:
May 27, 2008
Assignee:
Rigel Pharmaceuticals, Inc.
Inventors:
James B. Lorens, Todd R. Pray, Todd M. Kinsella, Mark K. Bennett