Abstract: Purified proteins, DNA sequences that code on expression therefore and recombinant DNA molecules, including hosts transformed therewith, for transforming coffee plants to suppress the expression of caffeine. The DNA sequences and recombinant DNA molecules are characterized in that they code on expression for an enzyme in the pathway for caffeine synthesis in coffee. Coffee plants transformed with DNA molecules that code on transcription for mRNA that is antisense to mRNA that codes on expression for at least one enzyme in the pathway for caffeine biosynthesis.
Type:
Grant
Filed:
March 26, 1996
Date of Patent:
June 13, 2000
Assignee:
University of Hawaii
Inventors:
John I. Stiles, Istefo Moisyadi, Kabi Raj Neupane