Patents Examined by Thomas A. Waltz
  • Process for preparation of anilines which are m-substituted by chlorine
    Patent number: 4460788
    Abstract: The invention relates to a process for the preparation of anilines which are m-substituted by chlorine, by selective dehalogenation of more highly chlorinated anilines in an acid medium in the presence of noble metal catalysts and in the presence of optionally substituted phenols.The 3-chloro- or 3,5-dichloroanilines obtainable by the process according to the invention are known intermediate products, and can be used for the preparation of plant protection agents.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: July 17, 1984
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karlfried Wedemeyer, Ferdinand Hagedorn, Werner Evertz
  • Process for the preparation of thiuram disulfides
    Patent number: 4459424
    Abstract: A process for the preparation of thiuram disulfides substituted with aliphatic cycloaliphatic, araliphatic, or aromatic hydrocarbon radicals, said process comprising reacting a suitably substituted secondary amine having a pK.sub.a .gtoreq.8 with carbon disulfide in a solvent and in the presence of oxygen or oxygen-containing gas, a solvent, and a metalliferous catalyst, at a temperature of between 0.degree. C. and 200.degree. C.
    Type: Grant
    Filed: February 16, 1982
    Date of Patent: July 10, 1984
    Assignee: Akzona Incorporated
    Inventors: Ludwig Eisenhuth, Hans G. Zengel, Manfred Bergfeld
  • Method for esterification
    Patent number: 4457868
    Abstract: A method for conducting transesterification reactions employing a catalyst system comprising metallic sodium and aluminum isopropoxide which provides a facile, high yield, means for producing compounds such as esters of alkyl- and alkyloxy-substituted arylamines.
    Type: Grant
    Filed: September 2, 1981
    Date of Patent: July 3, 1984
    Assignee: Mobil Oil Corporation
    Inventor: Milton Braid
  • Polyprenyl ketone derivatives
    Patent number: 4456558
    Abstract: This invention relates to novel polyprenyl ketone derivatives having the eral formula: ##STR1## in which n is an integer of 1-5, and R represents a hydroxymethyl, formyl or carboxyl group, and a process for the preparation of the same.
    Type: Grant
    Filed: October 16, 1981
    Date of Patent: June 26, 1984
    Assignees: Eisai Co., Ltd., General Director of the Agency of Industrial Science and Technology
    Inventors: Akio Sato, Kenji Nakajima, Yoshimasa Takahara, Shizumasa Kijima, Isao Yamatsu, Kouichi Suzuki, Takeshi Suzuki, Toshihiko Nakamura
  • 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
    Patent number: 4456552
    Abstract: This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: March 2, 1981
    Date of Patent: June 26, 1984
    Assignee: American Cyanamid Company
    Inventors: Keith C. Murdock, Frederick E. Durr
  • Phosphoramide derivatives and medicines containing the same
    Patent number: 4454126
    Abstract: Phosphoramide derivatives of the general formula: ##STR1## are disclosed wherein X and Y each represents a hydrogen atom or X and Y are removed to form a double bond between the respective adjoining carbon atoms, and n represents an integer of 0 to 2. A process for the preparation of these compounds and pharmaceutical compositions containing these phosphoramide derivatives are also disclosed. The phosphoramide derivatives of the invention are used to treat urethral calculosis and pyelonephritis.
    Type: Grant
    Filed: October 15, 1982
    Date of Patent: June 12, 1984
    Assignee: Eisai Co., Ltd.
    Inventors: Isao Yamatsu, Yuichi Inai, Takeshi Suzuki, Shinya Abe, Masaru Satoh, Naosuke Seto
  • Continuous production of azo pigments
    Patent number: 4454067
    Abstract: The invention relates to a process for the continuous manufacture of azo pigments, wherein a coupling component is reacted, inside a reaction zone filled with a previously produced suspension of the azo pigment to be made, with an aqueous solution of a diazo component at 10.degree. to 60.degree. C. and over periods of 0.2 to 4 hours.
    Type: Grant
    Filed: October 9, 1979
    Date of Patent: June 12, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hartmut Behringer, Kurt Karrenbauer, Heinrich Rehberg
  • Olive oil recovery
    Patent number: 4452744
    Abstract: Olive oil is recovered from olives by separating olive pits from olives to obtain a pitless olive meat, by maintaining the pitless olive meat at a temperature of about 70.degree. F. to about 110.degree. F., by introducing the pitless olive meat to an extraction zone, by withdrawing a liquid phase comprising olive oil, water, and a minor proportion of pulp from a first portion of the extraction zone, and by withdrawing a substantially dry solid olive pulp from a second portion of the extraction zone. The pulp and water are separated from the oil to obtain a pure olive oil. An inert additive is mixed with the pitless olive meat before extraction to increase the yield of product olive oil. Where olive culls are used as the starting material, the culls are wetted before the pits are separated.
    Type: Grant
    Filed: February 4, 1982
    Date of Patent: June 5, 1984
    Assignee: FPS Development Partnership
    Inventors: Harvey E. Finch, Salvatore P. Trapanese
  • N-Nitroxyalkylene benzamide derivatives
    Patent number: 4448989
    Abstract: A compound represented by the following formula ##STR1## wherein R represents a lower alkyl group having 2 to 6 carbon atoms, and n is an integer of from 1 to 5.
    Type: Grant
    Filed: December 20, 1982
    Date of Patent: May 15, 1984
    Assignee: Kowa Company, Ltd.
    Inventors: Masami Shiratsuchi, Hiroshi Ishihama, Yasumi Uchida
  • Hydroxyaminotetralincarboxamides
    Patent number: 4448990
    Abstract: o-Hydroxy tetralin carboxamides, substituted with an amino group in the aliphatic ring, are dopamine agonists.
    Type: Grant
    Filed: November 16, 1982
    Date of Patent: May 15, 1984
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld, Robert D. Titus
  • Cyclohexene derivatives
    Patent number: 4448991
    Abstract: Cyclohexenes of the formula ##STR1## wherein R.sup.1 is hydroxy or lower alkoxy; n is 1 or 2; R.sup.2 is lower alkyl; and R.sup.3 is hydrogen, lower alkyl, lower alkenyl or lower cycloalkylmethyl,and their pharmaceutically acceptable acid addition salts are disclosed. The compounds of formula I have analgesic activity and are useful for the control of pains.
    Type: Grant
    Filed: March 24, 1982
    Date of Patent: May 15, 1984
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hans Bruderer, Albert E. Fischli, Rudolf Pfister
  • Process for conversion of hydroxybenzenes to amines
    Patent number: 4448993
    Abstract: Hydroxybenzenes are converted to the corresponding amines by contacting the hydroxybenzene and ammonia at temperatures of about 250.degree.-550.degree. C. and pressures of about 0-5000 psig with a novel siliceous composition prepared by impregnating porous silica with aluminum hydride and subsequently heating the impregnated silica to a temperature of from about 300.degree. C. to about 900.degree. C. in a non-oxidizing environment.
    Type: Grant
    Filed: March 5, 1982
    Date of Patent: May 15, 1984
    Assignee: Shell Oil Company
    Inventor: Lynn H. Slaugh
  • 2-Ketosulfonamides
    Patent number: 4448988
    Abstract: The invention relates to new 2-ketosulfonamides of the general formula ##STR1## and to a process for their preparation, which process comprises oxidizing compounds of the general formulaR--CHOH--CH.sub.2 --SO.sub.2 NH.sub.2with manganese dioxide in a readily volatile, oxidation-stable organic solvent, preferably acetone or acetonitrile.
    Type: Grant
    Filed: April 21, 1982
    Date of Patent: May 15, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Dieter Gunther
  • Herbicidal arylsulfonamide derivatives of phenoxybenzoic acids
    Patent number: 4447634
    Abstract: There is provided herbicidal arylsulfonamide derivatives of phenoxybenzoic acids. These compounds are particularly useful when applied in a post-emergence application to soybean fields containing broadleaf weeds.
    Type: Grant
    Filed: April 30, 1981
    Date of Patent: May 8, 1984
    Assignee: Rhone-Poulenc Agrochimie
    Inventor: Guang-Huei Lee
  • Substituted bromofluorobenzene derivatives and process for its manufacture
    Patent number: 4446075
    Abstract: Substituted bromofluorobenzene, wherein the fluorine is in para-position and the bromine in meta-position to another substituent, is prepared by direct bromination of the corresponding fluorobenzene derivative. Bromination is advantageously carried out in the presence of a catalyst, preferably a metal or metal salt. The elementary bromine is used in an amount of 0.9 to 1.3 mols per mol of fluorobenzene derivative and the reaction temperature is between 20.degree. and 200.degree. C. The bromofluorobenzene derivatives are suitable for the synthesis of medicaments and plant protective agents.
    Type: Grant
    Filed: February 20, 1981
    Date of Patent: May 1, 1984
    Assignee: Riedel-de Haen AG
    Inventors: Kurt Eiglmeier, Reinhard Knieps
  • Process for the production of carnitine amide
    Patent number: 4443627
    Abstract: Process for the production of carnitine amide in the form of a chloride. The carnitine ethyl ester is obtained by reaction of 4-chloroacetoacetic acid ethyl ester with trimethyl amine and the subsequent hydrogenation is carried out with the help of a Pt/C catalyst. Such carnitine ethyl ester, without isolating it, is reacted with ammonia in an autoclave at -30.degree. to +10.degree. C. Everything is heated to 40.degree. to 80.degree. C. The mixture is stirred at such temperature at an ammoniac pressure of 8 to 24 atu. The product is filtered after cooling it to ambient temperature and counterbalancing the excess pressure. The product is then washed with alcohol and subsequently dried at 30.degree. to 50.degree. C. and at a pressure of 15 to 25 torr.
    Type: Grant
    Filed: January 20, 1982
    Date of Patent: April 17, 1984
    Assignee: Lonza Ltd.
    Inventors: Leander Tenud, Rene Blum
  • Enhanced carbon monoxide utilization in methanation process
    Patent number: 4441893
    Abstract: Carbon monoxide - containing gas streams are passed over a catalyst to deposit a surface layer of active surface carbon thereon essentially without the formation of inactive coke. The active carbon is subsequently reacted with steam or hydrogen to form methane. Surprisingly, hydrogen and water vapor present in the feed gas do not adversely affect CO utilization significantly, and such hydrogen actually results in a significant increase in CO utilization.
    Type: Grant
    Filed: November 5, 1982
    Date of Patent: April 10, 1984
    Assignee: Union Carbide Corporation
    Inventors: Louis F. Elek, Albert C. Frost
  • Controlled delivery of immiscible materials into an aqueous system
    Patent number: 4440542
    Abstract: Immiscible components are controllably released into aqueous systems by impregnating silica-silicate open cell foams with the immiscible components. As the silica-silicate foams are gradually dissolved, the immiscible components are released. Fragrance oils and dyes are particularly adaptable for use in the invention. In fact, silica-silicate foams impregnated with fragrance oils having polar functional groups, exhibit an unexpectedly slower rate of dissolution into aqueous environments and consequently, fragrance oils and dyes admixed therewith are released in aqueous systems over extended time periods.
    Type: Grant
    Filed: September 18, 1981
    Date of Patent: April 3, 1984
    Assignee: The Clorox Company
    Inventor: Lary L. Foley
  • Cysteine derivatives
    Patent number: 4440788
    Abstract: This invention relates to S-alkylcysteines and processes for preparing same. The compounds according to this invention are expected to be applicable as therapeutic agents for hepatic failures.
    Type: Grant
    Filed: December 30, 1981
    Date of Patent: April 3, 1984
    Assignee: Mitsubishi Chemical Industries, Limited
    Inventors: Hiroshi Terayama, Yoshiharu Morita, Kohei Umezu
  • Water-insoluble monoazo dyestuffs and their preparation
    Patent number: 4440681
    Abstract: Water-insoluble azo dyestuffs, their manufacture and use, which have the formula ##STR1## wherein D is a substituted phenyl or heterocyclic moiety which are free from ionic substituents and R.sup.1 is methyl or ethyl.
    Type: Grant
    Filed: April 24, 1981
    Date of Patent: April 3, 1984
    Assignee: Cassella Aktiengesellschaft
    Inventors: Horst Tappe, Rudolf Lowenfeld, Uwe Kosubek, Maria Kallay