Patents Examined by Thomas Waltz
  • Patent number: 4575571
    Abstract: A process for the stimulaneous halogenation and fluorination of aromatic derivatives substituted by at least one group containing a halogenoalkyl unit. The aromatic derivative is reacted with the halogen in liquid hydrofluoric acid. The products obtained are useful as intermediates for the synthesis of compounds having a plant-protecting or pharmaceutical activity.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: March 11, 1986
    Assignee: Rhone-Poulenc Specialites Chimiques
    Inventors: Michel Desbois, Camille Disdier
  • Patent number: 4572795
    Abstract: The invention is concerned with compounds of the formula: ##STR1## wherein: R.sup.1 is selected from the group consisting of hydrogen and methyl;R.sup.2 is selected from the group consisting of normal or terminally singly branched alkyl or alkenyl groups having four to seven carbon atoms provided that:(i) when R.sup.1 is hydrogen the alkyl group must have at least five carbon atoms, and(ii) when R.sup.1 is methyl, R.sup.2 is an alkyl group.This invention is also concerned with odorant compositions containing these compounds.
    Type: Grant
    Filed: January 26, 1983
    Date of Patent: February 25, 1986
    Assignee: Givaudan Corporation
    Inventors: Roman Kaiser, Dietmar Lamparsky
  • Patent number: 4571435
    Abstract: A process for the preparation of nitrogen fertilizers, especially oxamide, either indirectly or directly from oxalate esters, including the regeneration of the quinone oxidant utilized in the formation of the above esters. The process teaches preparation of oxamide, a potential slow-release nitrogen fertilizer via the oxidative carbonylation of alcohols with carbon monoxide in the presence of a catalytic amount of a platinum group metal salt and an optionally substituted quinone (substituted or unsubstituted 2,5-cyclohexadiene-1,4-dione) followed by ammoniation of the filtered reaction mixture at room temperature, or below. High yields of isolated oxamide were obtained by regulating the temperature and pressure during the oxidative carbonylation and maintaining essentially anhydrous conditions throughout the process. In addition, nearly quantitative yields of the hydroquinones (1,4-dihydroxybenzenes) are recovered for recycle along with the solvents, or for other commercial uses.
    Type: Grant
    Filed: December 3, 1981
    Date of Patent: February 18, 1986
    Assignee: Tennessee Valley Authority
    Inventors: Robert J. Radel, Jack M. Sullivan
  • Patent number: 4571408
    Abstract: An .alpha.,.beta.-dihydropolyprenyl derivative having the formula (I): ##STR1## wherein X represents a group of --COOR.sub.1 or --CH.sub.2 OR.sub.2 in which R.sub.1 is the hydrogen atom or an alkyl group having one to four carbon atoms and R.sub.2 is the hydrogen atom or an aliphatic acyl group having one to four carbon atoms; and n is an integer of one to four. A process for the preparation of the .alpha.,.beta.-dihydropolyprenyl derivative and a therapeutic agent for treatment of liver diseases comprising the same are also disclosed.
    Type: Grant
    Filed: October 20, 1983
    Date of Patent: February 18, 1986
    Assignee: Eisai Co., Ltd.
    Inventors: Isao Yamatsu, Yuichi Inai, Shinya Abe, Hideaki Watanabe, Toshiji Igarashi, Hiroyuki Shiojiri, Yoshio Tanabe, Kuniko Hara
  • Patent number: 4569689
    Abstract: Aniline derivatives of the formula ##STR1## where R.sup.1 is alkoxy, alkylthio, unsubstituted or substituted cycloalkoxy or the radical --NR.sup.2 R.sup.3, X is --CH.sub.2 --, --CH(OH)-- or --CO--, A is an unsubstituted or substituted alkylene chain, B is unsubstituted or substituted methylene or dimethylene, Z is hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy, and n is 1, 2 or 3, are used for controlling undesirable plant growth.
    Type: Grant
    Filed: June 14, 1984
    Date of Patent: February 11, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Ulrich Schirmer, Norbert Goetz, Bruno Wuerzer
  • Patent number: 4569801
    Abstract: The present invention relates to a new class of alkylsulfonamidophenylalkylamines which are potent antiarrhythmic agents having good oral bioavailability properties.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: February 11, 1986
    Assignee: Eli Lilly and Company
    Inventors: Bryan B. Molloy, Mitchell I. Steinberg
  • Patent number: 4568694
    Abstract: Cystamine derivatives of the formula: ##STR1## [wherein n represents 2 or 3, R.sup.1 and R.sup.2 each represents a hydrogen atom, or an alkyl group optionally substituted by a hydroxy, amino, alkylamino or dialkylamino group, or represents a cycloalkyl or aryl group, and X.sup.1 represents a group selected from the formulae .dbd.N--CN, .dbd.N--NO.sub.2, .dbd.N--COR.sup.3, .dbd.N--COOR.sup.3, .dbd.N--NH--CONH.sub.2, .dbd.N--SO.sub.2 R.sup.3, .dbd.CH--NO.sub.2, .dbd.CH--SO.sub.2 R.sup.3, .dbd.C(CN).sub.2, .dbd.C(CN)COOR.sup.3 and .dbd.C(CN)CONH.sub.2 (wherein R.sup.3 represents an alkyl or aryl group), or R.sup.1 represents a hydrogen atom, R.sup.2 represents an alkyl group optionally substituted by a hydroxy, amino, alkylamino or dialkylamino group, or represents a cycloalkyl or aryl group and X.sup.1 represents an oxygen or sulphur atom] have been found to be useful in the promotion of the growth of non-human animals including birds.
    Type: Grant
    Filed: June 15, 1983
    Date of Patent: February 4, 1986
    Assignee: May & Baker Limited
    Inventors: Richard M. Griffin, Malcolm N. Palfreyman
  • Patent number: 4568486
    Abstract: Described is the use in augmenting or enhancing the leather aroma of perfume compositions, perfumed polymers, colognes and perfumed articles of the diethyl ester of 2-isopropyl-3-oxosuccinic acid having the structure: ##STR1##
    Type: Grant
    Filed: October 1, 1984
    Date of Patent: February 4, 1986
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Chi-Kuen Shu, Cynthia J. Mussinan, Braja D. Mookherjee, Manfred H. Vock
  • Patent number: 4565887
    Abstract: N-Phenylsulfonyl-N'-pyrimidinyl- and -triazinylureas of the general formula ##STR1## and the salts of these compounds with amines, with alkali or alkaline-earth metal bases or with quaternary ammonium bases, have good pre- and post-emergence selective, herbicidal and growth-regulating properties.The symbols in this formula are as follows:A is a C.sub.3 -C.sub.6 -alkynyl group,E is the methine group or nitrogen,X is oxygen, sulfur or a sulfinyl or sulfonyl bridge,Z is oxygen or sulfur,m is the number one or two,R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl or C.sub.2 -C.sub.5 -alkenyl or a group --Y--R.sub.5,R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.2 -C.sub.5 -alkenyl or C.sub.1 -C.sub.4 -haloalkyl, or a group --Y--R.sub.5, --COOR.sub.6, --NO.sub.2 or --CO--NR.sub.7 --R.sub.8,R.sub.3 and R.sub.4 independently of one another are each hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylthio, C.sub.1 -C.sub.4 -haloalkyl, C.sub.1 -C.sub.
    Type: Grant
    Filed: January 19, 1984
    Date of Patent: January 21, 1986
    Assignee: Ciba-Geigy Corp.
    Inventors: Werner Fory, Karl Gass, Willy Meyer, Rolf Schurter
  • Patent number: 4565866
    Abstract: The instant invention relates to a process for the preparation of formamides in which ammonia, a primary or a secondary amine is reacted with carbon monoxide at an elevated temperature and pressure in the presence of a mixture consisting of a phenol and a phenate salt from the group consisting of an alkali metal phenate and an alkaline earth metal phenate, said phenol and said phenate salt each having the radical: ##STR1## wherein R is selected from the group consisting of an alkyl radical having from 3 to 18 carbon atoms and a hydroxyaryl radical of the formula: ##STR2## in which R' is an alkylene group having from 2 to 5 carbon atoms and in which x has a value of 1 to 2 when R is said alkyl radical and x has a value of 1 when R is said hydroxyaryl radical.
    Type: Grant
    Filed: January 24, 1984
    Date of Patent: January 21, 1986
    Assignee: Texaco Inc.
    Inventors: Roger G. Duranleau, John F. Knifton, George P. Speranza
  • Patent number: 4564639
    Abstract: A urea derivative of the general formula, ##STR1## (wherein X is a halogen), which has higher insecticidal activity than known similar compounds, with lowered toxicity to mammals and fishes. The derivative can be produced by reacting 2-fluoro-4-haloaniline with 2,6-difluorobenzoyl isocyanate or reacting 2-fluoro-4-halo-phenylisocyanate with 2,6-difluorobenzamide.
    Type: Grant
    Filed: March 1, 1983
    Date of Patent: January 14, 1986
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroshi Nagase, Yasuo Sato
  • Patent number: 4563348
    Abstract: A pheromonal compound produced by the western grapeleaf skeletonizer has been identified as sec-butyl (Z)-7-tetradecenoate. The synthetically-prepared compound demonstrates activity toward both the western grapeleaf skeletonizer, Harrisina brillians Barnes and McDunnough and the grapeleaf skeletonizer, Harrisina americana (Guerin). By attracting adult moths to field traps, this compound offers a useful tool in monitoring and control of this pest.
    Type: Grant
    Filed: January 31, 1983
    Date of Patent: January 7, 1986
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Edwin L. Soderstrom, William F. Haddon, Joel Myerson
  • Patent number: 4562208
    Abstract: The new N-sulphenylated ureas can be prepared by reaction of the corresponding N-substituted carbamic acid-fluorides and a primary or secondary amine in the presence of a diluent and an acid-binding agent. They have microbicidal properties and can be used in particular for the protection of industrial materials and of plants.
    Type: Grant
    Filed: February 15, 1983
    Date of Patent: December 31, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Engelbert Kuhle, Wilfried Paulus, Hermann Genth, Wilhelm Brandes, Paul Reinecke
  • Patent number: 4562206
    Abstract: A method for increasing cardiac contractility in a warm-blooded animal suffering from acutely depressed cardiac contractility which comprises administering to said animal an effective amount of a compound of the formula ##STR1## wherein R is hydrogen or isobutyrate, or a pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: March 8, 1984
    Date of Patent: December 31, 1985
    Assignee: Key Pharmaceuticals, Inc.
    Inventor: Ronald R. Tuttle
  • Patent number: 4560500
    Abstract: Described is a genus of norbornylbutadiene-acrolein adducts defined according to the structure: ##STR1## wherein one of X.sub.1 or X.sub.2 represents carboxaldehyde and the other of X.sub.1 or X.sub.2 represents hydrogen; wherein R.sub.1 and R.sub.2 taken together represent vinyl or ethylidene and R.sub.3 represents hydrogen or R.sub.2 and R.sub.3 taken together completes a cyclopenteno moiety and R.sub.1 represents hydrogen and uses thereof in augmenting or enhancing the aroma of consumable materials selected from the group consisting of perfume compositions, colognes and perfumed articles (e.g., perfumed polymers, solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softener compositions, dryer-added fabric softener articles, hair preparations, hair sprays, bath preparations and the like).
    Type: Grant
    Filed: May 24, 1984
    Date of Patent: December 24, 1985
    Assignee: International Flavors & Fragrances Inc.
    Inventor: Wilhelmus J. Wiegers
  • Patent number: 4560798
    Abstract: This invention pertains to the production of aminoethylethanolamine in high selectivity by the intermolecular condensation of monoethanolamine with itself. Selective intermolecular condensation is achieved by reacting monoethanolamine with itself at a temperature from 175.degree.-275.degree. C., and a pressure from 50-400 psig, said reaction being carried out in the presence of a rare earth metal or a strontium metal hydrogen phosphate.
    Type: Grant
    Filed: October 25, 1984
    Date of Patent: December 24, 1985
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Michael E. Ford, Thomas A. Johnson
  • Patent number: 4560820
    Abstract: A process for dealkylating alkylaromatic hydrocarbons using intermediate pore size zeolites substantially free of acidity is disclosed.
    Type: Grant
    Filed: October 25, 1984
    Date of Patent: December 24, 1985
    Assignee: Chevron Research Company
    Inventor: Leslie A. Field
  • Patent number: 4560499
    Abstract: Described is a novel genus of compounds defined according to the structure: ##STR1## wherein Z represents hydrogen, MgX and the moiety having the structure: ##STR2## and X represents chloro, bromo or iodo; as well as the novel compounds defined according to the structures: ##STR3## and mixtures of same shown according to the structure: ##STR4## wherein the wavy lines indicate both cis and trans juxtaposition of the hydrogen and methallyl moieties about the carbon-carbon double bond; uses of same as intermediates in a process for producing isosolanone which is a mixture of compounds having the structures: ##STR5## or shown by the single structure: ##STR6## and solanone which is a mixture of compounds having the structures: ##STR7## or shown by the structure: ##STR8## wherein the wavy lines are indicative of a cis or trans juxtaposition of the hydrogen or 2-propenyl moieties about the double bond; and organoleptic uses of the compounds having the structures: ##STR9##
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: December 24, 1985
    Assignee: International Flavors & Fragrances Inc.
    Inventors: John B. Hall, James M. Sanders, James N. Siano
  • Patent number: 4559361
    Abstract: Novel compounds of the formula: ##STR1## wherein R is phenyl-C.sub.1-6 alkyl, and salts thereof, have intraocular pressure depressant action.
    Type: Grant
    Filed: October 5, 1983
    Date of Patent: December 17, 1985
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventor: Yoshikazu Oka
  • Patent number: 4559409
    Abstract: The present invention relates to a process for manufacturing guanylurea sulfamate, whereby dicyandiamide and sulfaminic acid are reacted in an aqueous or organic-aqueous medium at a temperature within the range 70.degree. C.-105.degree. C. Guanylurea sulfamate is obtained in very good yield and high purity by this process.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: December 17, 1985
    Assignee: SKW Trostberg
    Inventor: Joachim V. Seyerl