Abstract: The present invention is directed to nanoparticulate compositions comprising a poorly soluble drug and at least one copolymer of vinyl pyrrolidone and vinyl acetate as a surface stabilizer adsorbed to the surface of the drug. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate composition of the invention, methods of making and using such nanoparticulate and pharmaceutical compositions.

Abstract: In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of a pharmaceutically active agent, wherein the agent is associated with a polymeric biocompatible material.

Abstract: Proposed is a reliable method for the preparation of a water-base hair-care or skin-care toiletry preparation capable of imparting the hair or skin of the user with excellent touch feeling of smoothness and sleekness. The method comprises (a) preparing an aqueous dispersion of globular particles of a cured silicone rubber having a specified average particle diameter by the in situ crosslinking hydrosilation reaction in liquid droplets of a vinyl group-containing dimethylpolysiloxane and an organohydrogenpolysiloxane in combination in the presence of a surface active agent and (b) admixing a base mixture consisting of the principal ingredients of a water-base toiletry composition with a specified amount of the aqueous dispersion of the cured silicone rubber particles.

Abstract: A water-soluble, foamable, insecticidally-active composition is disclosed. Also disclosed are methods for producing such a composition. The water-soluble, foamable, insecticidally-active composition comprises an aqueous phase, an insecticidally-active toxicant, and a foam-causing ingredient. The aqueous phase comprises water. The foam-causing ingredient must be capable of dispersing the insecticidally-active toxicant throughout the aqueous phase, to produce a toxicant-in-water dispersion. The foam-causing ingredient is present in an amount effective to enable the toxicant-in-water dispersion to form-in-place a water-soluble and insecticidally-active foam. The water-soluble aspect of the foam allows dissolving the foam (utilizing sufficient water) when desired.