Abstract: Stabilized nanoparticles capable of being filtered under sterile conditions and including at least one hydrophobic, water-insoluble and non-water-dispersible polymer or copolymer (and optionally an active principle) emulsified in a solution of phospholipids and an oleic acid salt.
Abstract: New solid formulations ofA) at least one agrochemical active compound,B) at least one additive from the groups mentioned in the description,C) at least one dispersant,D) at least one carrier andE) if appropriate, further active compounds and/or additives,a process for preparing the solid formulations and their use for treating plants.A new device for preparing new granules.
Type:
Grant
Filed:
March 22, 1993
Date of Patent:
June 27, 1995
Assignee:
Bayer Aktiengesellschaft
Inventors:
Peter Feyen, Uwe Priesnitz, Raphael Weischollek, Wolfgang Thielert, Stefan Dutzmann, Dieter Feucht, Ulrike Wachendorff-Neumann
Abstract: Pharmaceutical delivery systems containing 7-dimethyl-6-deoxy-6-demethyltetracycline or a non-toxic acid addition salt thereof comprising mixtures of a minor proportion of slow-release blended polymer coated spherical granules adapted to release part of the minocycline in a medium having a pH of below 3.9 and the rest in the range of from about 4.0 to about 7.5 and a major proportion of coated or uncoated quick-release granules adapted to release minocycline in a medium having a pH of less than about 3.9 and oral dosage unit form capsules containing the above are provided. These systems and formulations provide enhanced therapeutic blood levels of minocycline for at least about 24 hours when administered to a subject only once-a-day, regardless of whether the patient is fed or fasted. Methods for the preparation of the systems and formulations are provided as well.
Type:
Grant
Filed:
March 2, 1992
Date of Patent:
November 16, 1993
Assignee:
American Cyanamid Company
Inventors:
Nitin V. Sheth, Joseph J. Valorose, Jr., Keith A. Ellway, Madurai G. Ganesan, Kieran G. Mooney, Jerry B. Johnson
Abstract: The two components of the putty, one containing the accelerator and the other containing the catalyst, are placed in two separate containers under vacuo. After the preparation is complete the containers are brought first to atmospheric pressure and then to high pressure in order to favor the removal of the two materials from the containers onto the slab to be coated. The two components are then mixed on the slab forming the putty suitable for coating slabs of marble, stone and the like.