Abstract: An accommodating intraocular lens includes an adjustable optic, wherein the optic is capable of being moved between an accommodated state and an unaccommodated state. The optic includes an anterior portion, a posterior portion, and a sidewall between the anterior portion and the posterior portion. The lens further includes a ring disposed about the optic sidewall and a haptic coupled to the ring. The haptic is capable of being coupled to a patient's capsular bag. A method for implanting an accommodating intraocular lens is also provided.

Abstract: A spinal stabilization system includes an implant and instrumentation for stabilizing the spine. In one embodiment, the system includes a plate having a side rail and a channel extending adjacent the side rail. A pedicle screw assembly is positioned in the channel in releasable engagement with the side rail. The pedicle screw assembly includes a polyaxial screw seated in a lower housing having a lower locking flange. An upper housing having an upper locking flange secures the plate to the lower housing. The side rail of the plate is releasably engaged between the upper locking flange and the lower locking flange. The upper and lower housings include on-board locking mechanisms for fixing components in the screw assembly. The screw assembly and plate are inserted and oriented by remote manipulation. Minimally invasive techniques for inserting the implant are performed with the instrumentation, and cause minimal disturbance to surrounding tissue.

Abstract: Conformable end sealing stent for treating aortic aneurysms with acute angulation having an end portion with a circumference and configured to exert a radial force against an inner wall of the aorta, said end portion comprised of one or more filaments formed into at least three intertwined curved loops, each loop having a first and second end and a curved section which curved section is shaped and sized to extend at least halfway around the circumference.

Abstract: A tubular prosthesis is radially deformable and includes a lattice that is deformable between a retracted state of small diameter and an expanded state of larger diameter. The prosthesis includes at least two outer hooks delimiting between them a clamp for engaging in an outer tissue. The two hooks are carried by the lattice and can be moved between a spaced-apart position in which the clamp is open and a closer-together position in which the clamp is closed. The prosthesis includes a guiding member for moving at least one of the hooks during deformation of the prosthesis. The guiding member delimits a guide passage in which at least one of the hooks is engaged.

Abstract: A system of ophthalmic lenses contains a first lens for a first eye of a subject and a second lens for a second eye of a subject. The first lens includes a first lens shape having a first base refractive power and a first diffractive pattern imposed on the first lens shape, the diffractive pattern having a first lower diffraction order with a first lower diffractive power and a first higher diffraction order with a first higher diffractive power. The first lens includes lower and higher optical powers equal to the first base refractive power plus the first lower and higher diffractive powers, respectively. The second lens includes a second lens shape having a second base refractive power and a second diffractive pattern imposed on the second lens shape, the second diffractive pattern having a second lower diffraction order with a second lower diffractive power and a second higher diffraction order with a second higher diffractive power.

Abstract: A multi-element accommodating intraocular lens (AIOL) having a first anterior translation member and a first posterior translation member coupled together to form a first bias element. The first posterior translation member has a greater resistance to bending than the first anterior translation member. The first posterior translation member has a greater thickness than the first anterior translation member.

Abstract: Disclosed is an intraocular lens that is inserted inwardly into a capsular sac. One embodiment of the present invention provides an intraocular lens inserted inwardly into a capsular sac including an optic portion including a first optic body whose central region has a smaller thickness than a circumference of the central region and a second optic body coupled to the first optic body and whose central region has the same or higher thickness as/than the first optic body; and a haptic portion including a connection bar coupled to the optic portion and first support bar coupled to a circumference of the connection bar to be in contact with an inner surface of the capsular sac.

Abstract: Disclosed is an intraocular lens assembly provided inside a capsular sac. The intraocular lens assembly according to one embodiment of the present invention includes an intraocular lens and an intraocular lens supporter, and therefore the intraocular lens assembly may be useful to transfer a force to the intraocular lens, inserted inwardly into the capsular sac, to allow the intraocular lens to move like a natural eye lens, the force being generated from the ciliaris muscle and transferred through the zonule of Zinn and the capsular sac.

Abstract: An intra-ocular artificial lens with variable optical strength, having at least two optical elements, at least two of which are movable relative to each other in a direction extending transversely of the optical axis, wherein the optical elements have a form such that in different positions of the movable optical elements the artificial lens has a different optical strength, wherein the artificial lens has a fixed, positive optical basic strength wherein the variable optical strength caused by the relative movement of the movable elements is added to obtain the total optical strength of the artificial lens. Providing a different form results in the possibility of incorporating the greatest optical power in one of the optical elements. This optical element can then be optimized for the desired optical properties. The remaining optical element or the remaining optical elements can then be dimensioned for variation of the optical strength.

Abstract: A device includes a plurality of ringlets connected together to form a ring having a longitudinal axis. Each ringlet includes a first element and a second element. The first and second elements each extend from a first end through a central portion to a second end. The first and second ends are disposed at radially outer positions with respect to the ring than the central portion. The central portion is longitudinally displaced from the first and second ends. The first and second elements are separated and spaced apart from each other at the central portions thereof and are joined together at the first ends thereof and the second ends thereof. The ringlets are connected together such that the first ends of the elements of one ringlet are connected to the second ends of the elements of an adjacent ringlet.

Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract: An interior bag for a capsular bag of an eye comprises a discriminatingly permeable interior bag that selectively reduces fluid flow volume through the interior bag. The interior bag is secured inside the capsular bag. A structure, adapted to hold a refractive device, is attached to the interior bag.

Abstract: An apparatus and method for reducing and fixing fractures, for example, a proximal humeral fracture. A jacking device releasably attached to a locking plate presses against an inferior aspect of the head to rotate the head into anatomic alignment. Suture material stitched into the soft tissue superior to the head pulls the superior end of the head and guides and steers the head. The suture material passes through suture holes in the superior end of the plate. The jacking device positions and holds the head in an anatomic neck/shaft angle, thereby allowing the head to be fixed to the locking plate. In one such embodiment, a swivel bushing in the plate receives the jacking device and allows the angle of the device to be adjusted as desired. To aid in the fluoroscopic visualization during surgery, a radiolucent retractor is used to avoid blocking the surgeon's view.

Abstract: Annuloplasty device for implantation adjacent an annulus of a tricuspid valve, the annulus comprising anterior, posterior and septal aspects adjacent anterior, posterior and septal leaflets, respectively, of the tricuspid valve, the device comprising: a ring body comprising: an anterior portion, a posterior portion and a septal portion shaped to conform to, and for implantation adjacent, the anterior, posterior and septal aspects of the annulus, respectively; and first and second ends; wherein the ring body is curvilinear, with substantially no flat portions, forming a shape, and the ends are configured such that when the device is implanted, the first end will be located near the junction of the septal and anterior aspects of the annulus and the second end will be located near the septal aspect of the annulus. Related methods.

Abstract: Described are methods, devices, and systems for occluding or ablating vascular vessels. Noninvasive procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous valve insufficiency. Further described is the cooperative use of an angiogenic remodelable material with one or more sclerosing agents to cause closure of a targeted bodily vessel.

Abstract: The invention provides a transcorneal vision assistance device implantable in the eye of a patient. A preferred embodiment transcorneal microtelescope vision assistance device is implantable in the eye of a patient and includes a keratoprosthesis configured to replace a portion of the cornea of a patient and to secure the keratoprosthesis to a remaining front portion of the cornea. A microtelescope is carried by the keratoprosthesis for transcorneal mounting of the microtelescope.

Abstract: An arthrodesis implant is for a finger joint of a hand of a patient. The arthrodesis implant may include an extramedullary proximal anchor including a first member having a fastener-receiving passageway therethrough to receive a fastener to anchor the first member to an extramedullary portion of a proximal bone of the finger joint of the hand of the patient. The arthrodesis implant may also include an intramedullary distal anchor having a second member for being anchored within an intramedullary portion of a distal bone of the finger joint of the hand of the patient, and a coupling for securing the first and second members together.

Abstract: The disclosure relates to a flow-deflecting medical device comprising a support structure and two flow-deflecting members attached to the support structure. The first flow-deflecting member is movable to a position in which it contacts and substantially seals against the second flow-deflecting member.

Abstract: An ocular implant including a hydrophobic pseudo-endothelial implant and a binding agent applied thereto, the binding agent capable of bonding the implant to a posterior portion of a cornea such that the implant serves as a water barrier enabling dehydration of the cornea.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.