Abstract: Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology, for example, is directed to a catheter apparatus including an elongated shaft defined by a braid embedded within a polymer. The braid can include one or more thermocouple assemblies intertwined with a braiding element. The thermocouple assemblies can be coupled to one or more electrodes at a distal portion of the shaft.

Abstract: The system includes a pump, a heat exchanger, a bladder, a thermometer, and a controller. The heat exchanger is in fluid communication with the pump. The bladder is configured to be placed over a carotid artery, and is in fluid communication with the heat exchanger. The thermometer is located with respect to the heat exchanger and configured to measure a temperature of fluid downstream from the heat exchanger. The controller is in electrical communication 28 with the thermometer and the heat exchanger. The controller is configured to 20 control power delivered to or flow through the heat exchanger such that the temperature of the fluid downstream from the heat exchanger measured by the thermometer is between 2 degrees C. and 10 degrees C. for between 10 minutes and 50 minutes.

Abstract: Provided herein are systems, compositions, and methods for improving one or more skin characteristics in a subject. These systems, compositions, and methods are configured to cool the subject's skin at a target site to a degree that alters adipocyte signaling but does not produce significant destruction of subcutaneous lipid-rich cells. In some embodiments, alteration of adipocyte signaling produces an improvement in one or more skin characteristics.

Abstract: The present invention provides methods and devices for controlling a cold slurry that is delivered to a target tissue and for limiting heat transferring from surrounding tissue to the target tissue. In particular, a balloon structure is deployed at or near a point of delivery to act as a physical and/or thermal barrier. In some instances, the balloon structure can act as a pressure device obstructing the flow of warm blood into a treatment area, which can melt the cold slurry.

Abstract: A device for ablating target tissue of a patient with electrical energy is provided. An elongate shaft includes a proximal portion and a distal portion, and a radially expandable element is attached to the distal portion. An ablation element for delivering electrical energy to target tissue is mounted to the radially expandable element. The device can be constructed and arranged to ablate the duodenal mucosa of a patient while avoiding damage to the duodenal adventitial tissue. Systems and methods of treating target tissue are also provided.

Abstract: An electrosurgical device is provided that includes a probe extending in a longitudinal direction and having a proximal region and a distal region. An inner diameter of the probe defines a lumen. The probe has an electrically insulated portion extending from the proximal region to the distal region and an electrically exposed conductive portion located at the distal region. The electrically exposed conductive portion delivers radiofrequency energy to an area of tissue adjacent the distal region. The device also includes a heat transfer system for removing thermal energy from the area of tissue that is in thermal contact with the area of tissue. The heat transfer system removes from about 0.1 Watts to about 50 Watts of energy from the tissue. In addition, the heat transfer system can sufficiently draw heat away from the tissue without the use of a peristaltic pump for circulating a liquid inside the lumen.

Abstract: A neonatal drape device for protecting a neonatal subject comprising a sheet configured to receive the neonatal subject in a supine position. The sheet has a base, at least one side edge, and a plurality of separation lines. The separation lines extend inwardly from the at least one side edge of the sheet. The sheet is sufficiently pliable so as to wrap and conform to the neonatal subject. The sheet further includes a plurality of notches disposed adjacent to the base, each at an inner end of one of the separation lines. The notches are configured to allow a cable to extend from an internal space of the neonatal drape device to an external location while the sheet is wrapped around the neonatal subject.

Abstract: In a high voltage, variable frequency radiation generation system, a carrier signal supplied to a primary coil of a transformer is varied, e.g., turned ON and OFF at variable frequencies. The ON duration and/or the average amplitude of the carrier signal may also be varied. Moreover, the carrier signal may be modulated using an audio signal. The parameters to control the variation of the carrier can be provided as a recipe via a software application. A server can provide different types of apps providing different control features. The server may also collect user characteristic data and recipe usage data, and may facilitate exchange of these data and may recommend recipes based on a particular user characteristic.

Abstract: Embodiments of medical devices and methods are disclosed. The medical devices typically comprises an elongate member with a proximal region and a distal region. The distal region comprises a flexible portion that is more flexible than the proximal region of the medical device. The flexible region includes gaps in the sidewall of the elongate member. Furthermore, the medical device comprises a rigid energy delivery device at the distal end which is configured to deliver energy to tissue when energy is supplied to the energy delivery device. In some embodiments, the medical device comprises a support spine configured to provide support to the flexible portion of the elongate member.

Abstract: The present disclosure relates to a cold and hot thermal treatment device. Hot heat and cold heat are produced by a heat production unit and are periodically and repeatedly transferred to a heat transfer unit that is in contact with a human body such that a temperature is not suddenly changed but is gradually changed. Thus, the device may be used when diagnosing whether vascular reactivity is maintained in corresponding hands and feet, may generate a temperature stimulus, and may repeatedly perform the temperature stimulus, thereby improving the vascular reactivity.

Abstract: Presented are an apparatus, method and electrosurgical device for surgical procedures. An exemplary apparatus includes a body comprising a longitudinal axis and an electrical wire maintained within the body extending along the longitudinal axis, and an electrode extending from a distal end of the body operably coupled to the electrical wire, the electrode with the electrical wire operable to conduct a flow of current at a plurality of levels. The apparatus further includes a first button arranged on an external surface of the body, the first button operable for selecting the flow of current at each one of the plurality of levels through the electrical wire and the electrode, and a second button arranged on the external surface of the body adjacent the first button, the second button operable activate and deactivate the flow of current to the electrode.

Abstract: A personal patient warming apparatus includes a blanket having at least one pneumatic pathway formed therethrough and a plurality of orifices formed through at least one side thereof through which warmed air can exit to warm a patient. The blanket further includes a first portion configured to cover a first appendage of the patient when the blanket is disposed over the patient and a second portion configured to cover a second appendage of the patient when the blanket is disposed over the patient. Both the first portion and the second portion each include at least one tear line configured to form, when torn, an opening in the blanket through which at least one of the patient's appendages and an operating room table appendage board is disposed when disposing the blanket over the patient.

Abstract: An electrosurgery system includes a first generator configured to output an operating signal. The system also includes a pathway for the operating signal, the pathway includes an active electrode and a patient pad. The system also includes a circuit configured to measure a complex impedance of the patient pad. The circuit includes a second generator configured to output a measuring signal. The system also includes a voltage transformer, a current transformer, and a plurality of filters.

Abstract: A directable, portable appliance in combination with an adjustable set-point digital temperature controller for non-contact remotely monitoring infrared temperatures of a selected area of human skin and activating an electrical fan for directing cooling air over the selected skin areas of individuals experiencing episodes of thermal chaos, i.e., hot flashes.

Abstract: A balloon for renal nerve modulation is disclosed. The balloon may include a polymer material forming a balloon wall having an outer surface and flexible circuits comprising a base selectively adhered to the exterior surface of the balloon wall. Adhesive is selectively applied to the outer surface of the balloon, to the flexible circuit or to both such that the adhesive is selectively deposited on the at least a portion of the at least two pads or on the at least a portion of the at least two pads and to a portion of the distal spline. The portion of the at least two pads or the portion of the at least two pads and a portion of the distal spline are adhered to the outer surface of the balloon and a remainder of the flexible circuit moves freely with respect to the outer surface of the balloon.

Abstract: A thermal control unit for controlling a patient's temperature includes a fluid outlet for delivering temperature-controlled fluid to a patient, a pump, a heat exchanger, and a controller that automatically implements a step change in the temperature of the fluid delivered to the patient. The step change is implemented prior to the patient reaching a target patient temperature. In the moments after (and in some cases the moments before) the step change, the controller monitors the rate of change of patient's temperature to evaluate whether the patient will reach the target patient temperature without reversing the step change, and/or how long it will likely take for the patient to reach the target patient temperature without reversing the step change. The controller then determines whether to reverse the step change or to switch to another algorithm for controlling the fluid temperature.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange and/or surface heat exchange.

Abstract: A radiant heat foot warming device including a top planar surface configured to emanate radiant heat therefrom to warm feet of a user; a bottom planar surface spaced apart from the top planar surface; a plurality of curved sidewalls positioned between and connected to the top planar surface and the bottom planar surface; and an adjustable temperature control member positioned on the top planar surface that displays device temperature and further adjustably controls device temperature to regulate radiant heat emanating from the top planar surface.

Abstract: A thermal control unit supplies temperature controlled fluid to a patient to control the patient's temperature. The thermal control unit includes a fluid outlet, fluid inlet, heat exchanger, pump, patient temperature probe port, user interface, and controller. The controller receives patient temperature readings from the patient temperature probe port and controls a temperature of the circulating fluid in a first manner when no event data is received regarding treatment of the patient. The controller controls a temperature of the circulating fluid in a second and different manner when event data is received. The event data may relate to medication and/or fluid administered to the patient. The different manners include determining a target fluid temperature in using different inputs and/or alarming in different manners. In some cases, the controller pauses the use of the patient temperature readings while continuing to deliver temperature controlled fluid to the patient.

Abstract: The present invention generally relates to improved medical devices, systems, and methods. In many embodiments, devices, systems, and methods for locating and treating a target nerve with cold therapy are provided. For example, a focused cold therapy treatment device may be provided that is adapted to couple with or be fully integrated with a nerve stimulation device such that nerve stimulation and focused cold therapy may be performed concurrently with the cryo-stimulation device. Improvements in nerve localization and targeting may increase treatment accuracy and physician confidence in needle placement during treatment. In turn, such improvements may decrease overall treatment times, the number of repeat treatments, and the re-treatment rate. Further, additional improvements in nerve localization and targeting may reduce the number of applied treatment cycles and may also reduce the number of cartridge changes (when replaceable refrigerant cartridges are used).