Abstract: A rapid and direct assay for detecting of a virus having a characteristic enzyme in clinical samples in which (1) the clinical sample is contacted in solution with a substrate for the enzyme which includes a chromogen that is cleaved from the substrate by the enzyme and a precipitating agent that reacts with the liberated chromogen to form a precipitate (2) filtering the solution to concentrate the precipitate and (3) visually observing the concentrated precipitate for the characteristic color of the chromogen.
Type:
Grant
Filed:
October 16, 1992
Date of Patent:
October 12, 1993
Assignee:
Symex Corp.
Inventors:
Avraham Liav, James F. Maher, Craig D. Shimasaki, C. Worth Clinkscales, Michael D. Roark