Abstract: A composition includes diamine oxidase for use in prevention or treatment of symptoms and disorders caused by fibromyalgia or chronic fatigue syndrome.

Abstract: An aqueous eyebrow cosmetic includes a clay mineral, a film-forming polymer emulsion, and water, in which the content of the clay material is 5 to 20% by mass based on the total amount of the aqueous eyebrow cosmetic, the film-forming polymer emulsion includes a polymer having a glass transition temperature of ?20° C. or higher, and the content of the water is 30% by mass or greater based on the total amount of the aqueous eyebrow cosmetic.

Abstract: The present invention relates to functional foods comprising DAO and their use for the prevention or treatment of diseases or pathological conditions associated with high levels of histamine in blood, in particular for the prevention or treatment of migraine, chronic fatigue, fibromyalgia, spondylitis and pain caused by muscle contractures.

Abstract: There is provided a solid dosage form adapted for the release of a biologically active material in the oral cavity wherein the dosage form includes at least one biologically active material, and at least one matrix forming agent, wherein the dosage form substantially dissolves in the oral cavity. A method of producing the same and a kit including the same are also provided.

Abstract: A topical copper ion treatment in basic form composes a copper ion-containing solution composed of a biocompatible solution containing copper ions obtained by leaching of the copper ions from copper metal into the solution. The copper ion-containing solution can be combined with various carriers to form various forms of the copper ion treatment including creams, gels, lotions, foams, pastes, tampons, solutions, suppositories, body wipes, wound dressings, skin patches, and suture material. A method of making the copper ion-containing solution involves placing solid copper metal in a quantity of a biocompatible solution and maintaining the solution at a specified temperature for a predetermined period of time during which copper ions each from the copper metal into the solution, and thereafter separating the solution from the solid copper metal.

Abstract: A topical composition that destroys an external hyperplastic tissue, while preserving a basic architecture of the external hyperplastic tissue rather than dissolution of hydrolysis of protein peptide bonds of the external hyperplastic tissue, thereby providing a timely regeneration of healthy skin tissue after the external hyperplastic tissue has been treated with the topical composition, and thereby contributing to less damage to surrounding healthy skin tissue, as a result of, destructive potential of the topical composition being effectively neutralized and penetration of the topical composition into the surrounding healthy tissue being effectively blocked. The topical composition includes a caustic portion and a detoxifying and cleansing portion. The caustic portion has a caustic effect on the external hyperplastic tissue.

Abstract: An organic counteranion co-assembly strategy is employed to prepare a hybrid molecular framework. The hybrid molecular framework comprises an ordered arrangement of cyclodextrin (CD), metal cations, and organic anions.

Abstract: The disclosure relates to thermal control of compositions for altering the color of hair, in particular to hair bleaching compositions comprising thermal control agents, hair color-altering compositions comprising the hair bleaching compositions and/or thermal control agents, methods for preparing and using the hair color-altering compositions, and kits comprising the hair bleaching compositions and/or thermal control agents.

Abstract: Injectable compositions that can be added to parenteral nutrition are provided. In particular, a stable injectable composition is provided which includes water, and at least one of about 800 ?g to about 4,000 ?g of zinc, about 40 ?g to about 400 ?g of copper, from about 4 ?g to about 90 ?g of selenium, or from about 1 ?g to about 80 ?g of manganese per 1 mL of the injectable composition. Methods of preparing and using of the stable injectable composition are also provided.

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure containing a therapeutically effective amount of asenapine, such asenapine TTS for use in a method of treatment, processes of manufacture of such TTS as well as asenapine and transdermal therapeutic systems containing asenapine for use in a method of treatment and to a method of treating a human patient by transdermal administration of asenapine.

Abstract: Techniques regarding the transportation of molecular cargo across the BBB are provided. For example, one or more embodiments described herein can comprise a chemical compound to facilitate molecular encapsulation of the molecular cargo. The chemical compound can comprise a diblock copolymer having a molecular backbone comprising a polycarbonate structure and a polyethylene glycol structure. Also, the polycarbonate structure can be functionalized with boronic acid.

Abstract: A tattoo ink formulation method that employs utilization of glass microspheres to create a tattoo ink that can be removed if desired by an individual having a tattoo created with the tattoo ink. The present invention employs a first and second embodiment both utilizing glass microspheres to create a tattoo ink. The tattoo ink of the present invention is operable to be removed from a user through utilization of ultrasound. The first embodiment of the present invention employs an organic dye having an affinity for glass and as such is deposited onto the surface of the glass microspheres when immersed in a solution. The second embodiment of the present invention includes treatment of the glass microspheres in order to render the surface thereof hydrophobic. Ensuing treatment of the glass microspheres the glass microspheres are immersed in a solution containing an organic dye with limited solubility to create a tattoo ink.

Abstract: The invention discloses persistent antimicrobial protection of hands and/or surfaces of different objects using the hydro-alcoholic gel composition of the present invention. In particular, the invention provides water-resistant sanitizing hydro-alcoholic gel compositions based on ethyl alcohol, silver nanoparticles and fatty acids of Tung seed oil (Aleurites fordii). More particularly, it discloses the compositions that keep the surface sanitized well beyond the instant sanitization provided by volatile ethyl alcohol. The compositions of the present invention have ‘natural origin’ index of minimum 99% as per ISO 16128-2.

Abstract: The invention relates to a scaffold material comprising a plurality of particles of a highly porous polymeric material, characterized in that said scaffold material becomes a shapeable paste once hydrated. The specific features of the particle material impart a special behavior to the scaffold, which can be easily shaped and even highly reversibly compressed, so that in certain aspects it can, if needed, be injected, said capacity to be shaped being maintained over a high range of hydration conditions. A particular aspect of the invention relates, therefore, to the use of such scaffold material for the manufacturing of shapeable body implants, such as breast implants, to the shapeable body implants themselves as well as to non-invasive methods for using thereof in creating or reconstructing a three-dimensional volume in a subject's body part.

Abstract: A shelf-stable concentrated antimicrobial composition and method of using same comprises: at least one cyclic carboxylic acid and/or salt thereof in an amount from about 1 wt. % to about 10 wt. %; at least one anionic surfactant in an amount from about 10 wt. % to about 35 wt. %; at least one non-surfactant strong acid having a pKa less than about 2.3 in an amount from about 2 wt. % to about 25 wt. %; and at least one chelating agent in an amount from about 0.1 wt. % to about 10 wt. %. The composition retains at least 90% of its original antimicrobial efficacy after storage for at least five years at room temperature, and is substantially free of hydrogen peroxide, sources of hydrogen peroxide, parabens, aldehydes, aldehyde releasing agents, phenols, biguanides, peroxycarboxylic acids, quaternary ammonium compounds, chlorine compounds, enzymes, and etchants.

Abstract: The present invention relates to pharmaceutical compositions of Eliglustat. In particular the present invention relates to stable amorphous Eliglustat premix having enhanced stability and dissolution properties. The present invention also provide a stable premix composition comprising amorphous Eliglustat or a pharmaceutical acceptable salt thereof, pharmaceutical compositions comprising the premixes, and processes for preparing the same. The compositions prepared in the present invention includes sublingual or mouth dissolving tablets, and capsules of Eliglustat and/or its pharmaceutically acceptable salts thereof and at least one pharmaceutically acceptable carrier.

Abstract: An oral hygiene composition includes a mixture of: (i) a carrier liquid; and (ii) a water-insoluble hydratable polymer fibers forming an entangled three-dimensional network of said water-insoluble hydratable polymer fibers in said carrier; wherein: said carrier liquid comprises one or more humectant in a concentration of total humectant in excess of 5 wt. % based on the weight of the composition; said composition has an elastic modulus G? and a loss modulus G?, and said elastic modulus G? is larger that said loss modulus G?; and said water-insoluble hydratable polymer fibers have a diameter of about 10 to about 20,000 nm and a length of at least 100 nm.

Abstract: Disclosed are insecticidal compositions and associated methods that comprise an insecticide, C2-4 alkylene carbonate, C2-6 polyalkylene glycol, and a block co-polymer of C2-5 polyalkylene glycol and C3-6 polyalkylene glycol.

Abstract: A porous material suitable for implant is disclosed comprising a large plurality of substantially spherical intercalated hollows in a polymer. The hollows are formed by combining the polymer with a fugitive material under heat and pressure and subsequently removing the fugitive material to reveal the hollows. Intercalation can be increased by subjecting the fugitive material to a coalescing compacting process prior to combining the fugitive material with the polymer. The porous material can be combined with a solid material such as a solid polymer to fabricate complex implantable materials with a variety of features.

Abstract: Provided herein are improved compositions and methods of making and using the same, the composition comprising a polymer and a ceramic present at a ratio of from 3:1 to 1:3 of polymer:ceramic by weight, wherein the composition comprises or is a composite of the polymer and the ceramic having improved printability and/or having an improved elastic modulus and/or improved stress at failure (e.g., as compared to a blend of the polymer and the ceramic). Improved medical implants incorporating the same are also provided.