Abstract: The invention provides new isoflavonoid and triterpenoid compounds isolated from a soybean phytochemical concentrate. The new compounds have exhibited cytotoxic activity against selected tumor cell lines. Pharmaceutical compositions comprising the new compounds and methods for use thereof are provided by the invention.
Type:
Grant
Filed:
April 19, 2002
Date of Patent:
September 26, 2006
Assignee:
Iowa Research, The University Foundation
Abstract: This invention concerns the use of compounds selected among 1,4?-D-glucuronans, and/or glycuronic polysaccharides derived from polymers of formula (I), and whereof the number of saccharide units is less than about 30, and/or esters and/or ethers corresponding to polymers of formula (I) or said oligosccahride derivatives, as phytosanitary products in applications related to their activity for amplifying the 1,3?-D-glucanase enzyme, and/or the 1,4?-D-glucanase, and/or the xyloglucan endotransglycolase.
Type:
Grant
Filed:
June 23, 2000
Date of Patent:
September 26, 2006
Assignee:
Centre National de la Recherche Scientifique
Abstract: This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
Abstract: By using a combination of amrubicin or a pharmaceutically acceptable salt thereof with another medicament for treating lung cancer (irinotecan, vinorelbine, gemcitabine, etc.), it is intended to provide medicaments for treating lung cancer having an improved antitumor therapeutic effect on lung cancer and reduced side effects. Lung cancer can be effectively treated using these medicaments.
Abstract: The invention relates to a series of polyglycoside derivatives that contain water-soluble cationic groups introduced into the molecule by reaction with the hydroxyl groups present in the starting polyglycoside molecule, with an epoxy cationic material. The materials are multifunctional, providing not only wetting, and conditioning, but also antimicrobial properties, making them ideal for personal care applications.
Type:
Grant
Filed:
September 15, 2003
Date of Patent:
August 1, 2006
Assignee:
Colonial Chemical
Inventors:
Dean A. Smith, David Anderson, Anthony J. O'Lenick, Jr.
Abstract: Methods and composisions for enhancing cellular function through protection of a tissue components such receptors, proteins, lipids, nucleic acids, carbohydrates, hormones, vitamins, and cofactors, by administering pyrophosphate analogs or related compounds.
Type:
Grant
Filed:
April 27, 2001
Date of Patent:
August 1, 2006
Assignee:
HealthPartners Research Foundation
Inventors:
William H. Frey, II, John Randall Fawcett
Abstract: The invention provides single-dose oral formulations for controlling an ectoparasite infestation on a companion animal for a prolonged time, said formulations comprising a spinosyn component, or a physiologically acceptable derivative or salt thereof, and a carrier in oral dosage form. It also provides methods for controlling such infestations comprising orally administering a single dose of these formulations to the animal.
Abstract: Compounds of formula I:
wherein Y, X, R1 and Ra are defined herein are in methods for treating or preventing a viral infections selected from herpes simplex virus, varicella zoster virus, respiratory syncytial virus and cytomegalovirus infections.
Type:
Grant
Filed:
September 22, 2000
Date of Patent:
June 24, 2003
Assignee:
BioChem Pharma Inc.
Inventors:
Francis J. Giles, Jean Bédard, Robert F. Rando
Abstract: A method for treating arrhythmia in mammals is provided comprising administering a low dose of an adenosine receptor agonist of the Formula I:
wherein R1 is an optionally substituted heterocyclic group, preferably monocyclic.