Patents Examined by Trevor Love
  • Patent number: 11034773
    Abstract: This document provides methods and materials related to treating cancer. For example, methods and materials for using particles (e.g., nanoparticles) containing (a) one or more molecules having the ability to bind to a cancer cell (e.g., a human breast cancer cell) and (b) one or more molecules having the ability to bind to an APC (e.g., a human macrophage) to treat cancer are provided.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: June 15, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Yon Son Betty Kim, Robert E. Wharen, Jr., Hengfeng Yuan, Wen Jiang
  • Patent number: 11033509
    Abstract: The present invention provides novel pharmaceutical compositions of dimethyl fumarate. The pharmaceutical compositions of the present invention comprises a first pharmaceutical bead composition and a second pharmaceutical bead composition, wherein the first pharmaceutical bead composition is an enterically coated immediate-release composition and the second pharmaceutical bead composition is an enterically coated controlled-release composition, wherein the first pharmaceutical bead composition and the second pharmaceutical bead composition both comprise dimethyl fumarate Methods of using the pharmaceutical compositions of the present invention for treating multiple sclerosis are also included.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: June 15, 2021
    Assignee: BIOGEN MA INC.
    Inventors: Shyam B. Karki, Peter Zawaneh, Cheuk-Yui Leung, Kalyan Vasudevan, Yiqing Lin, Jin Xu, Andrea Trementozzi, Ivan Nestorov
  • Patent number: 11033630
    Abstract: The present invention provides pharmaceutical compositions comprising a metal-desferrioxamine B complex or a combination thereof, for preventing, inhibiting, reducing or ameliorating neurodegeneration, thereby treating diseases, disorders, or conditions characterized by or associated with neurodegeneration; as well as methods of use.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: June 15, 2021
    Inventors: Mordechai Chevion, Vladimir Vinokur, Eduard Berenshtein
  • Patent number: 11027042
    Abstract: This disclosure provides a method of preparing a hydrocolloid adhesive that includes the steps of mixing one or more components to produce a continuous phase, heating the continuous phased to a predetermined temperature between about 135° C. to 170° C., adding a stabilizer to the continuous phase, reducing a temperature of the continuous phase to a second predetermined temperature below 99° C., adding a discontinuous phase to the continuous phase at the second predetermined temperature, and mixing the components of the discontinuous phase and the continuous phase to produce a uniform mixture. Further, the hydrocolloid adhesive includes a super absorbent material and 0.05% to 2% by weight of a peroxide.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: June 8, 2021
    Assignee: Sarasota Medical Products, Inc.
    Inventor: Walter F. Leise, III
  • Patent number: 10987379
    Abstract: The present invention in various aspects and embodiments provides methods and formulations for treating inflammatory conditions of the skin and/or conditions involving compromised skin barrier function. Such diseases include blistering diseases of the skin, hereditary defects in skin barrier function, hyperproliferative conditions involving the skin, conditions associated with aging or damaged skin, immunological disorders involving the skin, among others.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: April 27, 2021
    Assignee: URGO US, INC.
    Inventors: Mark Sampson, Svetlana Panicheva, Cary Schockemoehl
  • Patent number: 10980731
    Abstract: Disclosed is a topical skin composition. The composition can include water, caprylic/capric triglyceride, Butyrospermum parkii (shea) butter, Helianthus annuus (sunflower) seed oil, cetyl alcohol, glyceryl stearate, and beeswax.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: April 20, 2021
    Assignee: Mary Kay Inc.
    Inventors: Julia Collier, Michael Frushour, Kim Wilson
  • Patent number: 10966991
    Abstract: Dry powder formulations for inhalation containing a combination of an anticholinergic, a long-acting beta2-adrenoceptor agonist, and a corticosteroid are useful for the prevention and/or treatment of an inflammatory and/or obstructive airways disease.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: April 6, 2021
    Assignee: CHIESI FARMACEUTICI S.P.A.
    Inventors: Claudio Cafiero, Leonardo Ortenzi, Francesca Schiaretti
  • Patent number: 10960015
    Abstract: Provided is a fast-dissolving effervescent pharmaceutical formulation of pyridoxal-5-phosphate, and to the use thereof in the treatment of neonatal epilepsy and also of metabolic disorders with a need for pyridoxal-5-phosphate.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: March 30, 2021
    Assignee: Assistance Publique-Hopitaux De Paris
    Inventors: Stéphane Auvin, Thomas Storme, Pascal Vaconsin, Vincent Boudy
  • Patent number: 10959944
    Abstract: Dry powder formulations for inhalation comprising a combination of an anti-cholinergic, a long-acting beta2-adrenoceptor agonist, and, optionally, an inhaled corticosteroid are useful for the prevention and/or treatment of an inflammatory and/or obstructive airways disease.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: March 30, 2021
    Assignee: CHIESI FARMACEUTICI S.P.A.
    Inventors: Claudio Cafiero, Leonardo Ortenzi
  • Patent number: 10954347
    Abstract: The present disclosure relates to hydrogels and their use for repairing or supplementing body tissue. The hydrogels are capable of safe injection into patients through fine gauge needles and are suitable for repairing, supplementing, or replacing the nucleus pulposus of an intervertebral disc. Methods of manufacturing and methods of using the hydrogels of the present disclosure to repair or replace tissues are also disclosed.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: March 23, 2021
    Assignee: REGELTEC, INC.
    Inventors: Thomas P. Schaer, Peter Wilson, Erik Brewer, Anthony Lowman, Nigel Gordon Smith
  • Patent number: 10947347
    Abstract: There is provided herein an organofunctional polysiloxanes comprising hydroxyl polyester groups made by reaction of epoxy functional polyorganosiloxanes and oligmeric polyesters based on polyhydroxy carboxylic acids. There is also provided methods for making the organofunctional polysiloxanes and agricultural, coating, personal care and home care applications containing the organofunctional polysiloxanes.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: March 16, 2021
    Assignee: Momentive Performance Materials GMBH
    Inventors: Roland Wagner, Sebastian Maass, Narayan Mukherjee, Karl-Heinz Sockel, Katharina Streicher
  • Patent number: 10946101
    Abstract: A substantially surface active agent free composition which includes a hydrophobic solvent, and/or a petrolatum, a paraffin wax and/or a fatty alcohol, a fatty acid and/or a wax and/or shea butter, with and without a propellant. A substantially surface active agent free composition, further comprising, a tetracycline antibiotic, or a vitamin D derivative, or one or more other active agents. A method of treatment using a substantially surface active agent free composition.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: March 16, 2021
    Assignee: Vyne Therapeutics Inc.
    Inventors: Dov Tamarkin, Elana Gazal, Irakliy Papiashvili, Yohan Hazot, David Schuz, Rita Keynan
  • Patent number: 10905116
    Abstract: In some example, the disclosure relates to a fabric assembly comprising a flexible substrate including a top surface; a plurality of plates attached to the top surface of the flexible substrate and arrayed in a pattern such that a plurality of continuous gaps are defined between adjacent plates; and one or more antibacterial agents are contained in or on at least one of the substrate and the plurality of guard plates wherein the antimicrobial agents are selected to reduce the fabric assembly's surface population of at least one of bacteria, virus, mold, fungus, or algae.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: February 2, 2021
    Assignee: Higher Dimension Materials, Inc.
    Inventors: Young-Hwa Kim, Richard D. Olmsted, Nusrallah Jubran
  • Patent number: 10894017
    Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: January 19, 2021
    Assignee: XSPRAY PHARMA AB
    Inventors: Per Andersson, Thomas Meijer, Victor Söderberg
  • Patent number: 10894018
    Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: January 19, 2021
    Assignee: XSPRAY PHARMA AB
    Inventors: Per Andersson, Thomas Meijer, Victor Söderberg
  • Patent number: 10888534
    Abstract: A sterile, sulfite-free aqueous norepinephrine solution comprising up to about 0.2 mg/ml of norepinephrine concentration (as free base), a tonicity adjusting agent, at a pH where the norepinephrine is soluble which is packaged in a flexible plastic container, characterized by being storage stable for from about 12 months to about 24 months at room temperature of about 25° C.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: January 12, 2021
    Assignee: InfoRLife SA
    Inventors: Sergio Dusci, Sayan Dusci
  • Patent number: 10874614
    Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: December 29, 2020
    Assignee: XSPRAY PHARMA AB
    Inventors: Per Andersson, Thomas Meijer, Victor Söderberg
  • Patent number: 10874613
    Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: December 29, 2020
    Assignee: XSPRAY PHARMA AB
    Inventors: Per Andersson, Thomas Meijer, Victor Soderberg
  • Patent number: 10874100
    Abstract: A disinfectant composition that is capable of inactivating non-enveloped viruses as well as other microorganisms, such as gram negative and gram positive bacteria, fungi, parasites, enveloped viruses, etc., is provided. Through selective control over the nature of the acid(s) employed and the overall pH level, the present inventors have discovered that the composition can achieve rapid antiviral efficacy, particularly against non-enveloped viruses. Once applied to a surface (e.g., hard surface), the disinfectant composition forms a film that remains capable of providing residual antiviral activity. Notably, the present inventors have discovered that the use of a vinylpyrrolidone copolymer in combination with a polyquaternary ammonium polymer and cationic surfactant can have a synergistic effect on the stability of the film such that it can also achieve long-term, residual antiviral activity.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: December 29, 2020
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Amy L. Vanden Heuvel, Douglas R. Hoffman, Jeremy D. Paulsen, Rebecca Vongsa, Paige N. Anunson, Lisa M. Kroll, Corey T. Cunnington, David W. Koenig
  • Patent number: 10874612
    Abstract: Novel microsphere compositions for use in parenteral formulations are provided. The microspheres comprise a biodegradable polymer of a molecular weight greater than 10,000 daltons, an active therapeutic agent, and a cellulose-derived material such as ethyl cellulose, carboxymethyl cellulose, hydroxypropylmethyl cellulose, or sodium carboxymethyl cellulose. The microsphere compositions decreased deviation in mean microsphere diameter, improved drug entrapment, and improved microsphere stability.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: December 29, 2020
    Assignee: Adare Pharmaceuticals USA, Inc.
    Inventors: Nathan Dormer, Cory Berkland