Abstract: A method for automated classification of curve patterns associated with dynamic image data of a lesion in a subject in order to determine characteristics of the lesion. The method comprising the steps of loading the image data into an electronic memory means, producing a plot of signal intensity profile, converting the signal intensity profile into a contrast enhancement profile, detecting a reference enhancement profile having a highly positive slope over an initial enhancement period followed by a decreasing profile portion, deriving signature curve types based on the reference enhancement profile, classifying an enhancement curve for each pixel in a selected ROI into one of the derived signature curve types using all available time points and displaying a grid-plot of the classified enhancement curves for all pixels in the selected ROI, wherein the overall display of curves and heterogeneity provides visual indication of the characteristics of the lesion.

Abstract: A new and/or novel image analysis technique for quantitative assessment of motion-based testing for injury in a patient using universally available and affordable devices and techniques is provided and disclosed. A video of a test being performed can be processed to track the motion of markers and/or bodily landmarks in two or more dimensions to quantitatively describe motion, thereby removing the subjective aspects typically associated with motion-based testing. In an example, the pivot shift test is a commonly used test for evaluating rotational instability of the anterior cruciate ligament (ACL)-deficient knee. The pivot shift test's subjective grading scale can be quantified and refined using image analysis techniques.

Abstract: A photoelectric type pulse signal measuring method includes, obtaining a main-path light signal transmitted by a photoelectric transmitter and reflected back from a surface of skin having an artery underneath, obtaining at least one auxiliary-path light signal receiving an ambient light signal, and based on the at least one auxiliary-path light signal, adaptively filtering an ambient light interference from the main-path light signal and obtaining an adaptive filtration result; or obtaining at least one auxiliary-path light signal transmitted by the same photoelectric transmitter and reflected back from a surface of skin without any artery underneath, and based on the auxiliary-path light signal, adaptively filtering a motion interference from the main-path light signal; then extracting a pulse signal from the adaptive filtration result. The present invention can simply and effectively eliminate the ambient light interference or motion interference upon photoelectric pulse signal measurement.

Abstract: The present disclosure relates to a method for monitoring oxygen level of an environment. The method comprises receiving at least one image of the environment comprising plurality of users from a capturing device. Then, at least one region of interest of each of the plurality of users is detected in the at least one image. A video plethysmographic waveform is generated by analyzing the at least one region of interest. Further, Peripheral Capillary Oxygen Saturation (SPO2) based on the video plethysmographic waveform is determined. Thereafter, oxygen level of the environment is determined by averaging the SPO2 level of each of the plurality of users. The determined oxygen level of the environment is compared with predefined oxygen level of the environment and an appropriate action is performed based on the comparison.

Abstract: Apparatus and methods for deactivating renal nerves extending along a renal artery of a mammalian subject to treat hypertension and related conditions. An ultrasonic transducer (30) is inserted into the renal artery (10) as, for example, by advancing the distal end of a catheter (18) bearing the transducer into the renal artery. The ultrasonic transducer emits unfocused ultrasound so as to heat tissues throughout a relatively large impact volume (11) as, for example, at least about 0.5 cm3 encompassing the renal artery to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual renal nerves.

Abstract: A backing block for an ultrasonic transducer array stack of an ultrasound probe is formed as a composite structure of graphite foam impregnated with an epoxy resin. The epoxy resin penetrates the porous foam structure at least part-way into the depth of the graphite foam block and, when cured, provides the backing block with good structural stability. The composite graphite foam backing block is bonded to the integrated circuit of a transducer to provide high thermal conductivity away from the transducer and good acoustic attenuation or scattering of rearward acoustic reverberations.

Abstract: A method for transcranial magnetic stimulation (TMS) of a stimulation area of medical interest, combined with functional magnetic resonance imaging (fMRI) for visualization of the response of, for example neurons, is disclosed. An ultra-thin magnetic resonance coil, MR coil, positioned in the immediate vicinity over an area where the response of, for example neurons, is to be detected, and preferably sandwiched between the TMS coil and the area, provides an excellent signal-to-noise ratio. The TMS can be performed directly through the MR coil. A great deal of flexibility in the number of the TMS and MR coils in use and their spatial arrangement is provided. A corresponding system for the TMS/fMRI studies is also provided.

Abstract: The invention comprises a virtual window system that creates a visual coherency between the image of the patient and his or her anatomy and the patient by aligning the image of the patient anatomy on the display to the patient and presenting the image to the user that feels as if the user is looking directly into the patient through the display. The invention is designed to also display medical devices, such as a minimally invasive tool. The system substantially unifies the coordinate systems of the patient, the medical device, the display, and the physician's hands. The invention creates a visual coherency between the motion of the medical device in the image and the motion of the physician's hands manipulating the device. This invention also creates a visual coherency between the motion of the image in the display and of that display.

Abstract: A needle access assembly and method for obtaining percutaneous needle access with little or no fluoroscopy. The method can include selecting a target for percutaneous access, directing a laser guide at a desired needle-insertion angle and in line with the selected target, aligning the needle access assembly with the laser, and inserting the needle into the target.

Abstract: High-speed three-dimensional reconstruction of elasticity data is obtained by acquiring a sparse set of data in planes sharing a common axis line and angularly arrayed about the axis line. The axis line may be an RF ablation probe and the reconstruction may enforce a circumferential smoothness in the reconstruction about the probe, as is compatible with an ablation volume.

Abstract: A method and apparatus for non-invasively determining a concentration of glucose in a subject using optical excitation and detection is provided. The method includes emitting an exciter beam (B1) to irradiate a portion (130) of tissue of the subject, causing physical and chemical changes in the surface, and causing an initial back scattering (D1) of light. The method further includes periodically emitting a probe beam (B2) which irradiates the portion of tissue and causes periodic back scatterings (D2) of light. The initial and periodic back scatterings are detected and converted into electrical signals of at least the amplitude, frequency or decay time of the physical and chemical changes, the back scatterings being modulated by the physical and chemical changes. By differentiating over time at least one of the amplitude, frequency or decay time of the physical and chemical changes, the concentration of glucose may be determined.

Abstract: A photoacoustic wave induced in a subject to be examined by illumination of the subject to be examined with light is detected. A first photoacoustic image corresponding to a frequency component less than or equal to a predetermined frequency and a second photoacoustic image corresponding to a frequency component higher than a predetermined frequency are generated based on a detection signal of the detected photoacoustic wave. The first photoacoustic image and the second photoacoustic image are combined together by placing, on a pixel in the first photoacoustic image the pixel value of which is less than or equal to a threshold, a pixel in the second photoacoustic image corresponding to the pixel in the first photoacoustic image.

Abstract: An ultrasonic handpiece includes a horn and a transducer system. The transducer system is configured to detect a first pressure applied to at least a first portion of the transducer system, transmit a signal associated with the first pressure, and generate ultrasonic vibratory energy. The first pressure is associated with a second pressure applied to the horn.

Abstract: A system and method for monitoring a health status of a subject. The system comprises: a medical device implantable in the subject and having a passage or compartment through which blood flows through; a sensor device embedded at or near a surface of said passage within said medical device for generating signals suitable for measuring a Doppler shift effect occurring within said passage; and a control device coupled to said sensor device for measuring a liquid blood flow rate within said passage based on sensor generated signals outputs. The embedded sensor device comprises a first piezo-electric element configured to generate an acoustic excitation signal and a second piezo-electric element configured to receive said acoustic excitation signal. The second piezo-electric element emits a signal responsive to said acoustic excitation signal. Control device in real time compares a generated output signal with the input excitation signal to determine a Doppler frequency shift measurement.

Abstract: Cross-calibration is provided for functional imaging. In PET or SPECT, the inaccuracies from the dose and detector sensitivity may be reduced or removed in both activity concentration and uptake. By using measures from both the radiotracer for the patient and factory calibrated sources, the variability due to dose may be removed. In SPECT, a measurement of system specific sensitivity to a factory calibrated point source is used to improve the accuracy of uptake values, not just activity concentration.

Abstract: An ultrasonic measurement apparatus includes a reception processing unit, a harmonic processing unit, a signal processing unit and an image generation unit. The reception processing unit is configured to receive, as a received signal, an ultrasonic echo corresponding to an ultrasonic wave transmitted toward a subject. The harmonic processing unit is configured to extract a harmonic component of the ultrasonic echo from the received signal. The signal processing unit is configured to add a weighting to the harmonic component by using a weight that varies depending on a value of the harmonic component. The image generation unit is configured to generate an image based on a signal to which the weighting has been added.

Abstract: An ultrasound imaging system and method employs hardware and/or software to monitor values indicative of analog-to-digital converter (ADC) saturation for each channel as a function of depth. Any of a number of actions may be performed based on the monitored values. For example, analog amplification or TGC may be adjusted to enhance the use of a dynamic range of ADCs while reducing or eliminating ADC saturation. A TGC profile may be adjusted. An alert may be provided. A power consumption may be adjusted.

Abstract: Disclosed are systems and methods for focusing ultrasound transducers that include multiple separate, independently movable transducer segments.

Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.

Abstract: Provided are: an ultrasound probe with excellent characteristic stability; and ultrasound equipment that uses the ultrasound probe. The ultrasound probe has an ultrasonic transmitting and receiving element provided with a substrate, an insulating film formed on the substrate, a cavity formed between the substrate and the insulating film, and a pair of electrodes disposed parallel to the substrate so as to sandwich the cavity. The ultrasound probe is characterized in that the ultrasonic transmitting and receiving element has a beam part with a multilayer structure formed by laminating films made of materials different in stress, the beam part being disposed on the electrode distant from the substrate out of the pair of electrodes, and the beam part is formed by laminating a film that applies tensile stress and a film that applies compressive stress.