Patents Examined by Venkataraman Balasubrasubramanian
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Patent number: 6605632Abstract: The invention concerns compounds of formula (I): R—A—R′ wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t—R5 group wherein t and R5 are as defined in the descriptionType: GrantFiled: November 10, 2000Date of Patent: August 12, 2003Assignee: Les Laboratoires ServierInventors: Daniel Lesieur, Frédérique Klupsch, Gérald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
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Patent number: 6570011Abstract: This invention relates to a process for the preparation of a stabilized aqueous alkali metal-2-hydroxy-4,6-dichloro-s-triazine (AHDT) solution, which entails starting at 5 to 40° C. with a solution containing either the corresponding alkali hydrogencarbonate, acetone, or a mixture thereof, and then, while cooling, adding cyanuric chloride and an alkali lye simultaneously in such a manner that the reaction temperature does not exceed 25° C. and the pH does not drop below 5.5, and during a subsequent stirring time of 2 to 30 hours adding either a very small quantity of alkali lauryl sulfate if the original starting solution contained hydrogencarbonate, or adding alkali hydrogencarbonate if exclusively acetone was used in the first reaction step, and then finally adding an alkali borate and/or a dialkali hydrogenphosphate and/or potassium hexacyanoferrate (II) as buffer. The pH, which should be ≧7.0 during the entire process, may, if necessary, be adjusted with an acid to a value between 8.0 and 9.5.Type: GrantFiled: March 8, 2001Date of Patent: May 27, 2003Assignee: Degussa AGInventor: Thomas Neumann
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Patent number: 6476224Abstract: The invention relates to a process for preparing ar(alk)yluracils of the general formula (I) in which A represents a single bond or represents alkanedlyl, Ar represents optionally substituted aryl, R1 represents optionally substituted alkyl and R2 represents hydrogen, halogen or alkyl, and to novel intermediates for this purpose and to processes for their preparation.Type: GrantFiled: February 14, 2001Date of Patent: November 5, 2002Assignee: Bayer AktiengesellschaftInventors: Bernd Gallenkamp, Reinhard Lantzsch, Lothar Rohe, Lubbertus Mulder
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Patent number: 6465645Abstract: Hindered amine compounds which are substituted by a long hydrocarbon chain are useful in a number of applications where the solubility or compatibility afforded by said substitution is needed. This is seen particularly for example with white, dyed, dipped, unscented and/or scented candle wax which is effectively stabilized against discoloration and fading by the incorporation therein of a long chain hindered amine alone or in combination with a UV absorber and/or an antioxidant.Type: GrantFiled: April 17, 2001Date of Patent: October 15, 2002Assignee: Ciba Specialty Chemicals CorporationInventors: Mervin G. Wood, Andrea R. Smith, James P. Galbo
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Patent number: 6459001Abstract: The subject of the invention is the products of formula (I): in which R1, R2, R3, R4, R5 and G are as defined in the description, the dotted lines represent an optional second bond, as well as the addition salts with acids and bases and the esters, their preparation process and the intermediates of this process, their use as medicines and the pharmaceutical compositions containing them.Type: GrantFiled: January 25, 2001Date of Patent: October 1, 2002Assignees: Aventis Pharma S.A., GenetechInventors: Serge Bernard, Denis Carniato, Jean-Francois Gourvest, Jean-Georges Teutsch, Jochen Knolle, Hans-Ulrich Stilz, Volkmar Wehner, Sarah C. Bodary, Thomas R. Gadek, Robert S. McDowell, Robert M. Pitti
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Patent number: 6455695Abstract: The present invention provides a process which enables easy and inexpensive preparation of alkylenebismelamines usable as components for forming resin materials, particularly aminoplasts, and flame retardants. The present invention is a process for preparation of alkylenebismelamines wherein the alkylene is a linear or branched C2-10 one by reacting an alkylenediamine wherein the alkylene is a linear or branched C2-10 one with melamine in the presence of an acidic catalyst under heating, characterized in that the amount of melamine is at least twice that of the alkylenediamine by mole.Type: GrantFiled: March 6, 2001Date of Patent: September 24, 2002Assignee: Nissan Chemical Industries, Ltd.Inventors: Hiroyuki Kousaka, Yasuyuki Nakajima
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Patent number: 6444674Abstract: The present invention relates to the use of pyrimidine compounds of the following formula: where R1, R2, R3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.Type: GrantFiled: August 29, 2001Date of Patent: September 3, 2002Assignee: Abbott LaboratoriesInventors: Beate Hellendahl, Annegret Lansky, Rainer Munschauer, Siegfried Bialojan, Liliane Unger, Hans-Jürgen Teschendorf, Karsten Wicke, Karla Drescher
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Patent number: 6409941Abstract: A product obtainable by transferring groups of formula (G-I) being present in a block oligomer having a polydispersity {overscore (M)}w/{overscore (M)}n of 1 to 1.7 and corresponding to formula (I) to groups of formula (Gu-II), wherein R1 is a hydrocarbyl radical or —O—R1 is oxyl; said transfer is carried out by reaction of the block oligomer with a hydroperoxide in a hydrocarbon solvent in the presence of a peroxide decomposing catalyst; n is a number from 2 to 14; R2 is for example C2-C12alkylene; A is for example —N(R4)(R5); R4 and R5 are for example C1-C18alkyl; R is preferably a group of formula (G-I) and B and B* have one of the meanings given for A; with the proviso that in the individual recurrent units of formula (I), each of the radicals B, R and R2 has the same or a different meaning. The products are useful as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials, in particular synthetic polymers.Type: GrantFiled: November 18, 1999Date of Patent: June 25, 2002Assignee: Ciba Specialty Chemicals Corp.Inventors: James Peter Galbo, Nicola Lelli, Valerio Borzatta, Jean-Pierre Wolf, Michael Ackerman, Piero Piccinelli
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Patent number: 6369137Abstract: Salt of a 1,3,5-triazine compound with polyphosphoric acid with a virtually linear structure, with the number average degree of condensation n being higher than 20, the content of the 1,3,5-triazine compound being higher than 1.1 mole per mole of phosphorus atom and the pH of a 10% slurry in water being higher than 4.5. Further, a process for the preparation of the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n that is higher than 20, by converting a 1,3,5-triazine compound with orthophosphoric acid at room temperature into the phosphate of the 1,3,5-triazine compound, after which this salt is converted at elevated temperature into a polyphosphate of the 1,3,5-triazine compound, and further flame retardant polymer compositions comprising the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n higher than 20.Type: GrantFiled: January 8, 2001Date of Patent: April 9, 2002Assignee: DSM N.V.Inventors: Johanna G. Kersjes, Renier H. M. Kierkels
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Patent number: 6362185Abstract: The present invention relates to medicaments comprising at least one compound of formula: wherein either R1 represents a —CH(Ra)—CHOH—CHOH—CH2OH chain and R2 represents a —CH2—CHOH—CHOH—CH2OH chain, or R1 represents a —CHOH—CHF—CHOH—CH2OH chain and R2 represents a —CH2—CHF—CHOH—CH2OH chain, or R1 represents a —CHOH—CHOH—CHOH—Rb chain and R2 represents a —CH2—CHOH—CHOH—Rb chain, or R1 represents a —CH2—CHOH—CHOH—CH2OH chain and R2 represents a —CH2—CHOH—CHOH—CH2OH chain, or R1 and R2 are identical and each represent a —(CHOH)n—CH2OH chain in which n is equal to 1, 2, 3 or 4, Ra represents an alkoxy radical (1-6 C in a straight or branched chain) or a fluorine atom, and Rb represents a carboxyl, —CO—NH2 or —CH2—NH2 radical, or one of their stereoisomers or theiType: GrantFiled: January 14, 2000Date of Patent: March 26, 2002Assignee: Aventis Pharma S.A.Inventors: Georges Bashiardes, Jean-Christophe Carry, Michel Evers, Bruno Filoche, Serge Mignani
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Patent number: 6342500Abstract: The present invention provides novel compounds, pharmaceutical compositions, methods, and kits for inhibiting the conversion of Amadori compounds to post Amadori advanced glycation endproducts, and for treating and preventing chronic tissue damage and diabetic complicationType: GrantFiled: March 3, 2000Date of Patent: January 29, 2002Assignee: Kansas University Medical CenterInventors: Raja Khalifah, Aaron Ashley Booth