Abstract: A vaso-occlusive system configured for embolizing an aneurysm, includes an implantable vaso-occlusive device coupled to a distal end of an elongate pusher and having a collapsed delivery configuration and an expanded, deployed configuration, wherein the vaso-occlusive device includes a proximal end configured to seat against the aneurysm adjacent the neck of the aneurysm, a distal end configured to extend in the sac and away from the neck of the aneurysm, and a central longitudinal axis, and wherein the vaso-occlusive device is configured to be releasably coupled to the distal end of the pusher at a releasable joint including either one or both of the configurations in the list consisting of: (1) the distal end of the pusher extends from the releasable joint at an angle formed with the central longitudinal axis of between about 30 degrees and about 120 degrees, and (2) the releasable joint is coupled at a location on the proximal end of the vaso-occlusive device that is radially offset from the central longit

Abstract: A device for application onto incisions or wounds with a liquid rapidly polymerizable adhesive for forming skin closure systems, comprising a flat porous mesh elongated along a longitudinal axis and having an upper side and an opposing lower or wound facing side and a central portion in immediate vicinity of the axis; further having a plurality of pores and windows in said mesh, said windows substantially larger than said pores and arranged along said longitudinal axis in said central portion; a crosslinking or polymerization accelerator or initiator disposed in or on said mesh; and a pressure sensitive adhesive disposed on at least a portion of the lower surface of said mesh.

Abstract: A surgical staple has two movable arms connected by a transverse connection area. Each one of the arms has a pinching area and a fastening end and the transverse connection area is deformable to allow the movable arms to be moved together by bending around the axis of the transverse connection area.

Abstract: A medical instrument system comprises an instrument manipulator configured to control a position of a medical instrument with respect to a base. The instrument manipulator comprises an instrument carriage comprising a medical instrument connector configured to engage the medical instrument. The instrument carriage is configured to translate along a linear axis to advance or retract the medical instrument with respect to the base. The medical instrument system also comprises an insertion stage slideably engaged with the instrument carriage along the linear axis. The insertion stage has a drive assembly comprising a drive belt and a drive motor configured to drive the drive belt. The base is fixedly coupled to the drive belt. The medical instrument system also comprises a connecting element having a distal end fixedly coupled to the drive belt and a proximal end fixed to the instrument carriage.

Abstract: Disclosed herein is a delivery system for delivering a leadless pacemaker. The delivery system may include a catheter, which may be a guide catheter. The catheter includes a distal end, a proximal end opposite the distal end, a lumen extending between the distal end and the proximal end, and a locking hub operably coupled to the proximal end. The locking hub includes a lumen segment of the lumen. In one implementation, self-biasing of the lumen segment places the lumen segment out of alignment with a rest of the lumen. Deflecting the lumen segment against the self-biasing of the lumen segment places the lumen segment in coaxial alignment with the rest of the lumen. In another implementation, self-biasing of the lumen segment reduces an inner diameter of the lumen segment and actuation of the locking hub expands the inner diameter.

Abstract: A surgical platform is disclosed. The surgical platform includes a component and a regional location tracking module configured to connect with an external device and receive geographic location data from the external device and implement geographic location specific functionality based on the geographic location data received from the external device.

Abstract: Described embodiments are directed toward centrally-opening, leaflet valve devices and systems for transcatheter delivery having a two-piece valve body as well as methods of making and delivering the two-piece valve devices. A transcatheter valve includes a collapsed configuration and an expanded configuration. The transcatheter valve can further include an everted configuration and a non-everted configuration.

Abstract: A dilation catheter includes a shaft and an expandable element. The shaft includes a proximal portion and a distal portion. The distal portion includes a tip and a bend. The tip is sized and configured to pass through an isthmus of a Eustachian tube (ET). The bend is proximal to the tip. The bend is formed at an angle configured to provide insertion of the tip into the isthmus of the ET via an ear canal associated with the ET. The expandable element is disposed at the distal portion of the shaft. The expandable element is configured to transition between a non-expanded state and an expanded state. The expandable element in the non-expanded state is configured for insertion into the ET via the isthmus. The expandable element in the expanded state is configured to dilate the ET.

Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

Abstract: Methods and apparatus for holding and maneuvering a valve during preparation and attachment to patient, providing increased visibility of the prosthetic valve and the sewing ring to prevent suture entanglement. A handle attachment is spaced from the valve for improved visibility of the sewing ring and the outlet end of the valve during attachment. Commissure posts are bent inward at the tips while preventing crashing of the commissure posts into each other causing damage. A release force needed to remove the holder and unthread the holder sutures is reduced. The holder and related methods can provide a kink free holder suture path to reduce suture entanglement and prevent damage to the implanted valve during holder removal by reducing the release force needed to remove the holder sutures by up to 30%.

Abstract: An intraocular lens implantation injector has a base body and elongated actuation element projecting into a base body rear section, movably guided along an actuation axis. Actuation element movement is generated selectively by axial push actuation or screw actuation about the axis. The actuation element features an external thread at least on one section. A switch element arranged to the base body is rotatable about or displaceable along the axis. The switch element features a spring arm, having an inner surface thread engagement structure facing the external thread. The base body inner surface forms an operative contact with a spring arm outer surface. The inner and/or outer surface is angularly inclined to the axis, or the inner surface features an inner radius varying circumferentially at least in sections about the axis. Switch element rotation/displacement generates spring arm elastic deformation towards/away from the axis, for selective thread engagement structure engagement.

Abstract: Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Deployment systems and methods for using the deployment systems described herein facilitate accurately and conveniently controllable percutaneous, transcatheter techniques by which the prosthetic heart valves can be delivered and deployed within a patient.

Abstract: An intraocular lens implantation injector has a base body and an elongated actuation element projecting into a base body rear section and movably guided along an actuation axis. Actuation element movement is generated selectively by axial push actuation or by a screw actuation about the axis. The actuation element features an external thread at least on one section. At least one spring arm arranged at the base body has an inner surface thread engagement structure facing the external thread. A switch element, interacting with the spring arm, is rotatably or displaceably arranged on the base body. The switch element interacts with the spring arm via an operative contact. At least one switch element inner surface and/or spring arm outer surface involved in the operative contact is angularly inclined to the axis. Switch element rotation/displacement generates spring arm elastic deformation towards/away from the axis, thereby engaging/disengaging the thread engagement structure.

Abstract: Suggested is a pacifier, comprising a mouthpiece and a shield further including a vibration-generating device.

Abstract: A surgical clip may include: a first leg member having an inner surface, an outer surface, and first and second side surfaces, the inner surface of the first leg member having a concave curvature; a second leg member having an inner surface, an outer surface, and first and second side surfaces, the inner surface of the second leg member having a convex curvature; at least one first tooth extending from a first lateral side of the inner surface of the second leg member; and a first channel defined between the first side surface and the inner surface of the first leg member. The first and second leg members may be configured to move between an open configuration and a closed configuration, and in the closed configuration, the at least one first tooth is received in the first channel.

Abstract: An ultrasonic surgical device including an elongate waveguide having a longitudinal axis and a distal end, and a blade extending away from the distal end of the waveguide, the blade including a curved portion that includes first and second opposed faces extending lengthwise along at least a portion of the length of the blade. Each of the first and second faces has a width that extends perpendicular to the longitudinal axis of the waveguide and a length that extends orthogonal to the width. A pair of hook portions are located on opposite sides of the blade. A method of fabricating an ultrasonic surgical device is also provided.

Abstract: A surgical tool guide comprises an anchor body extending between a proximal end and a distal end along an anchor axis. The anchor body has a piercing element at the proximal end. An angle adjustor arcuately extends between two opposed ends. The angle adjustor is mounted to the anchor body between the proximal end and the distal end. A guide body is cannulated along a longitudinal length thereof to define a guide passage extending along a guide axis. The guide body is mounted to the angle adjustor such that the guide axis intersects the anchor axis at a target surgical point and an angle is defined between the anchor axis and the guide axis. The anchor body and/or the guide body is displaceable relative to the other along the angle adjustor to vary at least one of the angle and a depth of the target surgical point.

Abstract: A hand-held gripping device that allows a surgeon to reach interior portions of a person's anatomy, includes a gripping portion having a pair of jaws and/or nets movable relative to each other between fully clamped and fully opened positions thereof, a handle portion spaced apart from the jaw portion by a bendable central portion that is hollow and corrugated, with a cord extending therethrough.

Abstract: A tissue-manipulating system including a tissue-manipulating device having shaft and a tissue grasper assembly. The tissue grasper assembly has at least one grasper arm resiliently expandable from a closed configuration, within and extending along the longitudinal axis of a shaft, to an open configuration outside the shaft with the grasper arm expanded in a direction transverse to the longitudinal axis of the shaft. In the open configuration, the at least one grasper arm may be engaged with tissue wall to manipulate or move the tissue wall, such as to move a distal tissue wall closer to a proximal tissue wall. The tissue grasper assembly may be deployable (such as by being separated from the shaft), such as to remain in place holding two tissue walls in apposition.

Abstract: A surgical system assembly is disclosed. The surgical system assembly includes a first surgical system and a second surgical system coupled to the first surgical system. The second surgical system includes a control circuit. The control circuit is configured to operate in a first mode or a second mode and control one or more functions of the first surgical system when the second surgical system is in the second mode.