Abstract: A heat exchanger is disclosed. The heat exchanger includes a heat exchanger core including a stacked plurality of plates, a top plate, and a bottom plate. The plurality of plates includes two end portion plates, and a plurality of intermediate plates stacked between the end portion plates. Each of the plurality of intermediate plates has a flow-through portion penetrating through the intermediate plates through which a fluid flows. Each of the through holes of each of the plurality of intermediate plates demarcates a flowthrough path which penetrates through the intermediate plate in the stacking direction and is isolated from the flow path between plates. A boss portion having a substantially elliptical shape edge portion is formed at each plate.
Type:
Grant
Filed:
March 22, 2023
Date of Patent:
July 22, 2025
Assignees:
Mahle International GmbH, MAHLE Japan Ltd
Abstract: A radiator joint is provided that include a first component, a second component and a weld seam, that together define a bird beak joint. The first component has generally circular cross-sectional profile. At an end of the first body there is a bird beak cut section that forms a first mating surface. The second component can function as a manifold. It has a generally rectangular cross sectional profile and an aperture. The aperture extends along at least two sides of the second component. The weld seam is disposed at the first mating surface and couples the first component to the second component. A fluidic seal is thereby formed between the hollow interior and the exterior while defining a fluid flow path through the first and second components.
Type:
Grant
Filed:
June 9, 2023
Date of Patent:
July 22, 2025
Assignee:
Transportation IP Holdings, LLC
Inventors:
George Wilson Fitzgerald, Anthony Roberts, Martin Richardson, Thomas Snelling, Balaji Hosadurgam Ravindranath, Leigh David
Abstract: A flow conduit intended for use in a fouling environment includes at least one solid surface of a thermally adaptive material. The at least one solid surface is configured to undergo a shape change as a result of thermal cycling such the shape change dislodges unwanted material accumulated on the at least one solid surface during operation of the flow conduit in the fouling environment.
Abstract: In one embodiment, a thermal management device includes a heat sink base and heat sink fins comprising a single element formed from a plurality of graphene layers with carbon nanotubes interposed between the graphene layers. A method is also disclosed herein.
Type:
Grant
Filed:
January 30, 2024
Date of Patent:
July 22, 2025
Assignee:
CISCO TECHNOLOGY, INC.
Inventors:
M. Baris Dogruoz, Mehmet Onder Cap, D. Brice Achkir, Joel Richard Goergen
Abstract: A fuel powered paint marker having a first stage and a second stage comprising: a housing; a combustion chamber; a piston; a compression chamber; a fuel system; an oxidizing system; an oxidizing agent; a fuel assembly included in the fuel system; a separation assembly included in the fuel system and separating the oxidizing agent from the fuel assembly in the first stage; a bolt drive system; a fuel nozzle included in the fuel system for injecting fuel into the combustion chamber during the second stage; and, an ignition for igniting the fuel and oxidating agent in the combustion chamber driving the piston forward and compressing a gas in the compression chamber thereby ejecting a projectile wherein the fuel and oxidizing agent are separated during the first stage and mixed in the combustion chamber.
Abstract: An accessory for a firearm includes a target sight for mounting to a portion of the firearm and a counter configured to count a total number of rounds fired by the firearm.
Type:
Grant
Filed:
May 26, 2023
Date of Patent:
July 22, 2025
Assignee:
SIG SAUER, INC.
Inventors:
Andrew W. York, Donald L Cramer, Richard Bradley Brumfield, John P. Nichols, Christopher J. Boudreau, David Pierson
Abstract: An assembly directing gas to an action of a firearm has a barrel with a bore and a forward sealing surface. A gas block has a bore, a port for directing gases from the block bore through the block port, a rearward sealing surface for sealingly mating with the forward sealing surface of the barrel, and a forward sealing surface. A component has a bore and is attached to a forward end of the barrel, the component bore being in fluid communication with the barrel bore. At least one port communicates the component bore with the block port, the component having a rearward sealing surface for sealingly mating with the forward sealing surface of the gas block. A portion of the component rearward of the rearward sealing surface is received within the bore of the gas block. The barrel and component cooperate to sealingly retain the gas block therebetween.
Abstract: A sound suppressor for a shotgun comprising a barrel is disclosed. The sound suppressor includes an outer frame, an inner hollow body including openings, a gas expansion area and a barrel attachment arrangement for attaching the sound suppressor onto the barrel. The sound suppressor is configured in such a way that when the sound suppressor is in use, the barrel is inside the outer frame and the shot of the shotgun passes through the inner hollow body, and the gases from the exploding propellant expand into the gas expansion area. The barrel attachment arrangement includes a first attachment part, a second attachment part, and a moving arrangement. The first attachment part is fixed to the frame, and the second attachment part is moved by the moving arrangement, which presses against the barrel to hold the sound suppressor in place.
Abstract: A buffer tube insert includes an elongated portion and one or more projections extending from the elongated portion. The one or more projections are configured for insertion into one or more corresponding notches on a buffer tube. Each projection includes a connection arrangement such as, but not limited to, a threaded interior for receiving a connection member such as, but not limited to, a set screw that can facilitate the restriction of movement between the buffer tube and a gunstock.
Type:
Grant
Filed:
June 7, 2023
Date of Patent:
July 22, 2025
Inventors:
W. Scott Hemphill, Austin T. Bender, M. Scott McCormick
Abstract: An adjustable tension device for use in connection with accessories designed to be worn inside of a user's waistband. The tension device is operable to attach to said accessory and provide an added point of leverage against the user's clothing, thereby holding the accessory snugly against the user's body. The tension device includes a base, and fixed arm, and a plurality of extensions of varying lengths, wherein said extensions are able to attach to the fixed arm, thereby providing varying arm lengths depending on the orientation of the accessory in relation to the user's body.
Abstract: A cloaking system for an aircraft is provided. Cameras on the aircraft can detect background colors during flight. Electroluminescent paint on the aircraft can be powered on that resembles the background color. The color and luminescence of the aircraft will allow for dynamic cloaking unachievable by prior art camouflage paint colors.
Abstract: Driver's cab for a utility vehicle, comprising an interior space enclosed by the driver's cab, a driver's cab floor, and a protrusion formed on the driver's cab floor, wherein the protrusion is curved away from the interior space, wherein the protrusion comprises a first contour defining the protrusion in a first sectional plane intersecting the driver's cab floor, wherein the first contour is curved in an arcuate manner at least in sections, wherein the protrusion comprises a second contour defining the protrusion in a second sectional plane intersecting the driver's cab floor, wherein the second contour is curved in an arcuate manner at least in sections, and wherein the first sectional plane and the second sectional plane are positioned perpendicular to each other.
Abstract: A method for defending a predetermined area from an autonomously moving Unmanned Aerial Vehicle (UAV) is provided. The method includes generating one or more adversarial example adapted to disrupt a machine-learning based vision system of the UAV. Additionally, the method includes determining, based on geographical information about at least one of the predetermined area and a surrounding area of the predetermined area, a respective position for the one or more adversarial example in at least one of the predetermined area and the surrounding area of the predetermined area.
Type:
Grant
Filed:
February 15, 2023
Date of Patent:
July 22, 2025
Assignee:
Sony Group Corporation
Inventors:
Francesco Cartella, Orlando Anunciacao, Karin Cvetko Vah, Olivier Elshocht
Abstract: Disclosed are a dart game apparatus and a dart game system with an illumination unit. The dart game apparatus includes: a dart target having a plurality of score areas; a sensing unit sensing a hit location of a dart pin in the dart target; a display area formed to surround an exterior of the dart target, provided in a body structure of the dart game apparatus, and disposed to output a variable screen to a location adjacent to at least a part of an outline of the dart target; a target illumination unit irradiating light to the dart target or a periphery of the dart target; and a controller controlling the target illumination unit.
Abstract: The present disclosure provides antibodies and antibody fragments thereof that bind to IL-23p19. The disclosed antibodies and antibody fragments thereof can modulate a biological activity of the IL-23 receptor signaling axis and are therefore useful for the treatment of immune-mediated inflammatory disorders.
Type:
Grant
Filed:
June 21, 2022
Date of Patent:
July 22, 2025
Assignee:
NOVAROCK BIOTHERAPEUTICS, LTD.
Inventors:
Haichun Huang, Ming Lei, Yi Pei, Han Li
Abstract: Provided herein are binding polypeptides that specifically bind DLL3. More specifically, provided herein are fusion proteins, including multivalent and/or multispecific contracts and chimeric antigen receptors, that bind DLL3. Also provided are pharmaceutical compositions containing the polypeptides, nucleic acid molecules encoding the polypeptides and vectors and cells thereof, and methods of use and uses of the provided DLL3 binding polypeptides for treating diseases and conditions, such as cancer.
Type:
Grant
Filed:
October 9, 2019
Date of Patent:
July 22, 2025
Assignee:
Inhibrx Biosciences, Inc.
Inventors:
Brendan P. Eckelman, Michael D. Kaplan, Katelyn M. Willis, Rajay A. Pandit, Angelica N. Sanabria, Sydney A. Barnes, Margaret E. Haerr, John C. Timmer
Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.
Type:
Grant
Filed:
September 25, 2024
Date of Patent:
July 22, 2025
Assignees:
Disc Medicine, Inc., Abb Vie Inc., Abb Vie Deutschland Gmbh & Co. KG
Inventors:
Maria Beconi, John Quisel, Brian MacDonald, Steven Robinette, Bernhard Mueller, Andreas Popp, Jennifer M. Perez
Abstract: The present invention relates to an anti-CD79B antibody, an antigen-binding fragment thereof, and a pharmaceutical use thereof. Furthermore, the present invention relates to a chimeric antibody and a humanized antibody comprising a CDR region of the anti-CD79B antibody, a pharmaceutical composition comprising the anti-CD79B antibody or the antigen-binding fragment thereof, and a use thereof as an anti-cancer drug. Particularly, the present invention relates to a humanized anti-CD79B antibody, and a use thereof in preparation of a drug for treating lymphoma (such as DLBCL).
Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD96 receptor protein (hu-CD96) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD96. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD96 binding to CD155, including effects arising from CD96 interactions with CD226 and/or TIGIT.
Type:
Grant
Filed:
November 18, 2022
Date of Patent:
July 22, 2025
Assignee:
23andMe, Inc.
Inventors:
Yu Chen, Chingwei Vivian Lee, Germaine Fuh-Kelly, Zuoan Yi, Yao-Ming Huang, Valentine Yeung, Krista Maureen McCutcheon, Samuel Nalle, Augusta Eleanor Broughton, Louise Scharf, Navneet Singh, Tina Thai, Shouhua Xiao
Abstract: A method for engineering less alloreactive immune cells, including T-cells that express chimeric antigen receptors (CARs), using a nucleotide sequence in form of an RNA encoding a anti-TCR CAR to achieve the transient expression of anti-TCR CAR at the cell surface. The transient expression of the anti-TCR CAR recognized by the alpha beta TCR on the cell surface unexpectedly enabled the a purification of the TCR-negative CAR expressing cells. The TCR-negative CAR expressing immune cells can be used in adoptive therapy to treat diseases associated with cell surface antigens, such as cancer with less side effects, in particular less GVHD.
Type:
Grant
Filed:
December 28, 2018
Date of Patent:
July 22, 2025
Assignee:
Cellectis
Inventors:
Alex Boyne, Laurent Poirot, Philippe Duchateau, Alexandre Juillerat