Patents Examined by (Vikki) Hon B. Trinh
  • Publication number: 20250257096
    Abstract: The present invention relates to a method for reducing lipopolysaccharides activity and/or lipopolysaccharides in a collagen-containing and/or collagen-derived product and products obtained by the method. The method comprises the steps of providing a collagen-containing and/or collagen-derived product comprising lipopolysaccharides, contacting the collagen-containing and/or collagen-derived product comprising lipopolysaccharides with a polyglycol ether of a fatty alcohol to provide a mixture and recovering a collagen-containing and/or collagen-derived product.
    Type: Application
    Filed: April 11, 2024
    Publication date: August 14, 2025
    Inventors: Ruben Jean Antoinette VAN DER MEEREN, Daniel ASDI BASKORO SEJATI
  • Publication number: 20250257106
    Abstract: Provided are a hybrid protein comprising a CFH functional unit and a DAF functional unit. an encoding nucleic acid thereof, and a method and use thereof for treating related diseases or disorders of a complement system.
    Type: Application
    Filed: April 6, 2023
    Publication date: August 14, 2025
    Inventors: Haili MA, Heng LIU
  • Publication number: 20250257110
    Abstract: This disclosure relates to, inter alia, cells expressing both a chimeric antigen receptor (CAR) and membrane bound IL-12 and the use of these cells to target and treat cancers (e.g., solid tumors and cancers expressing CD19, CD22, BCMA, PSCA, HER2, TAG-72, and PSCA). The disclosure also relates to cells expressing a membrane bound IL-12.
    Type: Application
    Filed: September 26, 2024
    Publication date: August 14, 2025
    Inventors: Saul J. Priceman, John P. Murad, Eric Lee
  • Publication number: 20250257116
    Abstract: An anti-cleavage mutant of CD16 for enhancing cell function is provided. Specifically, the CD16 mutant has an amino acid residue mutation at the following sites corresponding to a wild-type CD16: insertion of one or more proline between V196 and S197 sites and/or between S197 and T198 sites of CD16-F176V. The CD16 mutant of the present invention can resist the cleavage of ADAM17, and can enhance the ADCC capability of NK92 cell line expressing same.
    Type: Application
    Filed: April 13, 2023
    Publication date: August 14, 2025
    Inventors: Lei ZHANG, Yuan WANG, Rui ZU
  • Publication number: 20250257418
    Abstract: A fatigue-resistant load-bearing steel for a wind turbine main shaft, and a manufacturing method and a use thereof are provided. The manufacturing method includes: step S1, smelting: smelting a raw steel into a molten iron, followed by impurity removal and deoxidation, and adjusting contents of respective components to obtain a casting molten steel; step S2, continuous casting: crystallizing the casting molten steel with an electric pulse, followed by solidification to obtain a continuous casting billet; step S3, rolling: subjecting the continuous casting billet to rough rolling and finish rolling sequentially to obtain a finish-rolled billet; and step S4, post-rolling treatment: slowly cooling and then air-cooling the finish-rolled billet to obtain the fatigue-resistant load-bearing steel.
    Type: Application
    Filed: May 9, 2024
    Publication date: August 14, 2025
    Applicant: Zenkung Heavy Industry (Jiangsu) Co., Ltd.
    Inventors: Zhijie ZHAO, Liang XU, Zhen YUAN, Jia JU
  • Publication number: 20250257421
    Abstract: The present disclosure includes a differential heat treatment method for a forming roller including an outer circumferential surface heat treatment step for heating the outer circumferential surfaces of roller units. The method may additionally include a first natural cooling step for naturally cooling until the surface temperature reaches 100-150° C., an inner circumferential surface heat treatment step for heating the inner circumferential surfaces of the roller units. The method may additionally include a second cooling step for naturally cooling until the roller units reach a room temperature state after the inner circumferential heat treatment. Further, the method may include an inspection and release step for inspecting the hardness of the outer circumferential surface and the inner circumferential surface after the second cooling and releasing when the hardness is within an error range.
    Type: Application
    Filed: June 7, 2023
    Publication date: August 14, 2025
    Inventor: Sang Seok JEONG
  • Publication number: 20250257422
    Abstract: Provided are a material for hot stamping, wherein the material includes: a steel sheet including carbon (C) in an amount of 0.19 wt % to 0.25 wt %, silicon (Si) in an amount of 0.1 wt % to 0.6 wt %, manganese (Mn) in an amount of 0.8 wt % to 1.6 wt %, phosphorus (P) in an amount less than or equal to 0.03 wt %, sulfur (S) in an amount less than or equal to 0.015 wt %, chromium (Cr) in an amount of 0.1 wt % to 0.6 wt %, boron (B) in an amount of 0.001 wt % to 0.005 wt %, an additive in an amount less than or equal to 0.1 wt %, balance iron (Fe), and other inevitable impurities; and fine precipitates distributed within the steel sheet. The additive includes at least one of titanium (Ti), niobium (Nb), and vanadium (V), and the fine precipitates include nitride or carbide of at least one of titanium (Ti), niobium (Nb), and vanadium (V) and trap hydrogen.
    Type: Application
    Filed: April 29, 2025
    Publication date: August 14, 2025
    Inventors: Nu Ri Shin, Hun Chul Kang, Ji Hee Son, Byoung Hoon Kim
  • Publication number: 20250257423
    Abstract: The present disclosure is related to carbonation and selective ammonia leaching for the recovery of minor metals.
    Type: Application
    Filed: September 8, 2023
    Publication date: August 14, 2025
    Applicant: Phoenix Tailings, Inc.
    Inventors: Thomas Anthony Villalon, JR., Rita Marie Silbernagel, Henry Chase Hutcheson
  • Publication number: 20250257429
    Abstract: An aluminum alloy sheet for a can lid, the sheet including: 0.27 mass % or more and 0.39 mass % or less of Si; 0.35 mass % or more and 0.55 mass % or less of Fe; 0.17 mass % or more and 0.25 mass % or less of Cu; 0.75 mass % or more and 0.95 mass % or less of Mn, and 2.2 mass % or more and 2.8 mass % or less of Mg, wherein, in each of 0°, 45°, and 90° directions to a rolling direction, a minimum evaluation value Smin among evaluation values S calculated by a following formula (1) using a 0.2% yield strength ?0.2, a tensile strength OB, and an average value ?fm of the 0.2% yield strength and the tensile strength is 330 MPa or more and 390 MPa or less. S = ? fm / ( ? 0.
    Type: Application
    Filed: April 16, 2024
    Publication date: August 14, 2025
    Applicant: UACJ Corporation
    Inventors: Tomotaro EZAKI, Tomoyuki KUDO, Daichi TAKAI, Kiyonari TAZOE
  • Publication number: 20250257430
    Abstract: One aspect of the present disclosure provides an aluminum alloy sheet for a tab including 0.20 mass % or more and 0.60 mass % or less of Si, 0.30 mass % or more and 0.70 mass % or less of Fe, 0.11 mass % or more and 0.40 mass % or less of Cu, 0.7 mass % or more and 1.2 mass % or less of Mn, and 1.1 mass % or more and 3.0 mass % or less of Mg. A sheet thickness t (mm) and a tensile strength ?B_0° (MPa) in a 0-degree direction with respect to a rolling direction satisfy the following formula (1). In an L-ST cross-section, a percentage of a total area of Mg2Si particles having an area of 0.3 ?m2 or more is 0.2% or less. ( 2.7 × t - 0.
    Type: Application
    Filed: April 16, 2024
    Publication date: August 14, 2025
    Applicant: UACJ Corporation
    Inventors: Tomonori YOSHIDA, Yukimasa IKEDA, Tomoyuki KUDO
  • Publication number: 20250257436
    Abstract: Refractory-reinforced multiphase high entropy alloys (RHEA's) advantageously providing high strength and fracture toughness in an as AM-deposited solidified condition and other conditions are described.
    Type: Application
    Filed: November 22, 2024
    Publication date: August 14, 2025
    Inventors: Iver E. Anderson, Emma Marie Hamilton White, Duane Johnson, Nicholas Argibay, Andrew B. Kustas, Michael Chandross, Raymond V. Puckett
  • Publication number: 20250257437
    Abstract: A hot-stamped coated steel part includes a steel substrate and an aluminum alloy coating comprising, proceeding from steel substrate outwards, an interdiffusion layer and an outer layer. The total thickness of the coating ecoating and the thickness of the interdiffusion layer eIDL satisfy the following condition: 4 ? 0 ? E pc ? 80 ? with ? E pc = ( 3 ? 3 . 3 - e IDL 0 . 9 + e IDL - e coating ) 2 - 1 ? 4 ? 8 ? ( e IDL - e coating ) - ( 3 ? 3 . 3 - e IDL 0 . 9 + e IDL - e coating ) The hot-stamped coated steel part comprises an undeformed portion having a thickness ePflat from 0.6 mm to 3.5 mm, and at least one deformed portion. A lineic density of cracks dC in the coating in the undeformed portion is higher than or equal to a minimum lineic density of cracks dCmin(ePflat) defined as: dC m ? i ? n ( e pflat ) = 1 ? 5 . 5 + 9 ? 1 * e - 7.44 - 2 . 8 ? 8 * arctan ? ( 5.49 * ( e pflat - 1.
    Type: Application
    Filed: April 30, 2025
    Publication date: August 14, 2025
    Inventors: Clément PHILIPPOT, Doriane SERRA, Hubert SALMON LEGAGNEUR, David DUSSAUSSOIS
  • Publication number: 20250257443
    Abstract: A method for atomic-scale fabrication is provided. The method includes: positioning a growth substrate in a vacuum environment to minimize contamination and to enable precise deposition; heating the growth substrate to an elevated temperature; employing a focused electron beam to induce atomic-scale modifications of the growth substrate while at the elevated temperature; and supplying a source material for deposition through an in situ delivery system, wherein the in situ delivery system includes thermal evaporation of the source material. The focused electron beam induces localized defects or nucleation sites in the growth substrate, such that incoming atoms from the source material form chemical bonds with the localized defects.
    Type: Application
    Filed: February 7, 2025
    Publication date: August 14, 2025
    Inventors: Ondrej E. Dyck, Stephen Jesse, Andrew R. Lupini, Jacob Swett
  • Publication number: 20250257444
    Abstract: A Co—Cr—Pt-oxide-based sputtering target containing 50 at % or more of Co, more than 0 at % and 20 at % or less of Cr, and more than 0 at % and 25 at % or less of Pt, with the balance being one or more oxides and incidental impurities, wherein the sputtering target contains (A) a composite phase in which Co, Pt, and one or more oxides are mutually dispersed and (B) a metal Cr phase; and wherein the sputtering target comprises 10 or more metal Cr phases having an equivalent circle diameter of greater than 10 ?m and 100 ?m or less in a 1 mm×1 mm field of view under a SEM at a magnification of 50×.
    Type: Application
    Filed: June 1, 2023
    Publication date: August 14, 2025
    Inventors: Yasuyuki Goto, Toyokazu Eguchi, Yasunobu Watanabe, Jun Tadokoro
  • Publication number: 20250257451
    Abstract: Embodiments described herein generally relate to the fabrication of integrated circuits. More particularly, the implementations described herein provide techniques for deposition of amorphous carbon films on a substrate with improved etch selectivity. In certain embodiments, a method of forming an amorphous carbon film with film density close to the theoretical density of pure sp2 graphite and reduced hydrogen content is provided.
    Type: Application
    Filed: February 12, 2025
    Publication date: August 14, 2025
    Inventors: Ruiyun HUANG, Jun FENG, Yuxing ZHANG, Bryan LIAO, Abhijit KANGUDE, Amit Kumar BANSAL, Xinhai HAN, Karthik JANAKIRAMAN
  • Publication number: 20250257462
    Abstract: Disclosed is a method of depositing thin films, the method comprising supplying a metal precursor to the inside of a chamber where a substrate is placed to adsorb the metal precursor onto the substrate; purging the inside of the chamber; supplying a reactant to the inside of the chamber to react with the adsorbed metal precursor and form a thin film, wherein the metal precursor includes one or more halogen groups and one or more organic ligands.
    Type: Application
    Filed: February 7, 2025
    Publication date: August 14, 2025
    Applicant: EGTM Co., Ltd.
    Inventors: Kyu Ho CHO, Ha Na KIM, Hyun Ju JUNG, Ju Hwan JEONG, Hyeon Sik CHO, Sun Young BAIK, Tae Young LEE, Shin Beom KIM
  • Publication number: 20250257463
    Abstract: A semiconductor processing apparatus includes an outer tube, an inner tube in the outer tube and providing a process space, and a nozzle between the outer tube and the inner tube. The nozzle provides an internal passage. The inner tube provides a slit. The nozzle provides a plurality of holes. The plurality of holes are vertically spaced apart from each other. The slit vertically extends to expose at least two of the plurality of holes. The internal passage is connected to the process space through the slit and the plurality of holes.
    Type: Application
    Filed: May 1, 2025
    Publication date: August 14, 2025
    Inventors: MINJU LEE, SOOKYEOM YONG, SANGYUB IE
  • Publication number: 20250257468
    Abstract: We disclose novel methods for infiltrating gallium or an alloy thereof into a porous scaffold. Such methods include selecting or providing a porous scaffold; and using a centrifuge to at least partially fill the porous scaffold with gallium or an alloy thereof. The void fraction of the filled-coated scaffold is preferably no more than about 10%. In some embodiments and implementations, the methods further include forming a coating on the porous scaffold to enhance wetting of the scaffold to gallium before infiltration with the centrifuge. With the coating, the void fraction of the filled-coated scaffold may be advantageously reduced to be no more than about 2%. Cleaning step(s) may be further provided to remove oxides from the scaffolds before infiltration with the centrifuge.
    Type: Application
    Filed: February 12, 2024
    Publication date: August 14, 2025
    Inventors: Michael C. Fish, Rachel C. McAfee, Bruce R. Geil
  • Publication number: 20250257473
    Abstract: A wireline cable with zinc-coated steel armor wires exposed at its exterior, is protected from corrosion by fluid, such as drilling fluid, in a wellbore by application of a coating of a viscous liquid composition, which may be a thixotropic grease, onto the exposed armor wires. The viscous liquid composition includes a viscous carrier and at least one substance which is an oxygen scavenger. The cable may also be protected by application of such a coating as it is withdrawn from a wellbore and rewound onto a storage drum.
    Type: Application
    Filed: February 12, 2025
    Publication date: August 14, 2025
    Inventors: Evgeny Borisovich Barmatov, Trevor Hughes, Anatoly Vladimirovich Medvedev, Madhuri Gummadi
  • Publication number: 20250257487
    Abstract: A method of producing hydrogen and/or bromine by electrolysing hydrogen bromide using a fluoropolymer membrane having a glass transition temperature Tg?110° C. in an electrolysis of hydrogen bromide, wherein the hydrogen bromide stems from a bromination of a hydrocarbon.
    Type: Application
    Filed: July 24, 2023
    Publication date: August 14, 2025
    Inventors: Miroslav KETTNER, Thomas TUREK, Ulrich KUNZ, Heiner GRIMM, Nikolai NESTERENKO, Miguel Alexandre FIGUEIREDO SANTOS, Jingsong ZHOU