Patents Examined by Vivian Garner
  • Patent number: 5200553
    Abstract: Biologically active carboxylic acid esters which promote antitumor or immune response are selected from the group consisting of compounds having formulas (I), (II) and (III):XCH.sub.2 --CHX--CHX--C(.dbd.O)--O--Z (I)CH.sub.3 --CO--CH.sub.2 --C(.dbd.O)--O--Z (II)CH.sub.3 --CH.sub.2 --CO--C(.dbd.O)--O--Z (III)wherein X is H, or one X only may be OH; Z is --CHR--O--(O.dbd.
    Type: Grant
    Filed: July 25, 1988
    Date of Patent: April 6, 1993
    Assignee: Kupat Holim Health Insurance Institution of the General Federation of Labor
    Inventors: Abraham Nudelman, Matitiahu Shaklai, Ada Rephaeli
  • Patent number: 5183928
    Abstract: A hydroquinone monocarboxylate, e.g., hydroquinone monoacetate, is facilely prepared by disproportionating/reacting a stoichiometric excess of a hydroquinone dicarboxylate, e.g., hydroquinone diacetate, with hydroquinone, optionally in the presence of a strong acid/transesterification catalyst.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: February 2, 1993
    Assignee: Rhone-Poulenc Specialities Chimiques
    Inventor: Serge Ratton
  • Patent number: 5179232
    Abstract: A process for solubilizing solid formaldehyde oligomers without contaminating the solution product with undesirable solvent products by treating the oligomer with heated hydroxyacetic acid.
    Type: Grant
    Filed: December 19, 1990
    Date of Patent: January 12, 1993
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Edward J. Balthazar, Harold E. Bellis, Charles J. Denham
  • Patent number: 5159107
    Abstract: A process for the continuous preparation of alkyl pentenoates comprises the following steps:a) reaction of a butadiene-containing C.sub.4 cut with an alkanol and carbon monoxide in the presence of a cobalt carbonyl catalyst and heterocyclic aromatic tertiary nitrogen base at from 100.degree. to 160.degree. C. and under from 100 to 1,200 bar andb) treatment of the resulting reaction mixture, at the rate at which it is obtained, in a treatment zone, at from 100.degree. to 160.degree. C. under from 250 to 1,200 bar with a residence time of from 5 to 60 minutes, substantially without back-mixing.
    Type: Grant
    Filed: October 29, 1991
    Date of Patent: October 27, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Paul Panitz, Heinrich Reitz, Gunter Schuch, Wilfried Seyfert
  • Patent number: 5159099
    Abstract: A continuous process is described for preparing a di-alkyl carbonate, e.g. dimethylcarbonate, via oxidative carbonylation of the corresponding alkanol, e.g. methanol, in the presence of a catalyst system containing a copper alkoxy-halide and water with a mole ratio of the water to the copper salt of between 0.25 and 2.0 and preferably between 0.5 and 1. In this manner extremely high di-alkyl carbonate formation rates are obtained.
    Type: Grant
    Filed: August 6, 1991
    Date of Patent: October 27, 1992
    Assignee: Enichem Synthesis S.p.A.
    Inventors: Ugo Romano, Franco Rivetti
  • Patent number: 5155265
    Abstract: Acetic acid containing iodide, unsaturates and carbonyl impurities is purified by treatment with ozone and thereafter contacted with activated carbon and/or an ion-exchange resin for removal of impurities.
    Type: Grant
    Filed: April 19, 1991
    Date of Patent: October 13, 1992
    Assignee: Hoechst Celanese Corporation
    Inventors: Mark O. Scates, Russell K. Gibbs, Jr., G. Paull Torrence
  • Patent number: 5155266
    Abstract: Acetic acid containing iodide, unsaturates and carbonyl impurities is purified by treatment with ozone in the presence of an oxidation catalyst. The acetic acid product may be further contacted with activated carbon or ion-exchange resins for additional removal of impurities.
    Type: Grant
    Filed: April 19, 1991
    Date of Patent: October 13, 1992
    Assignee: Hoechst Celanese Corporation
    Inventors: Mark O. Scates, Russell K. Gibbs, Jr., G. Paull Torrence
  • Patent number: 5153339
    Abstract: Naphthoquinone having a purity of higher than 95% is separated from an aqueous slurry of naphthoquinone and phthalic acid prepared by contacting, with an aqueous medium, a reaction mixture gas containing naphthoquinone and phthalic anhydride formed by a catalytic vapor phase oxidation of naphthalene. An extraction of naphthoquinone is carried out with a chain or cyclic saturated hydrocarbon at 60.degree. to 110.degree. C. under the condition adjusting pH to 1.2 to 5 and substantially dissolving phthalic acid in the aqueous phase and leaving resinous materials as a bottom.
    Type: Grant
    Filed: June 25, 1982
    Date of Patent: October 6, 1992
    Assignee: Kawasaki Kasei Chemicals Ltd.
    Inventors: Ryo Matsuura, Tatsuyoshi Komatsu, Kenji Usui, Toru Sato
  • Patent number: 5151532
    Abstract: A process for the preparation of high-purity tetrachloro-1,4-benzoquinone by the action of hydrogen peroxide and hydrochloric acid on hydroquinone, which comprises causing 3.8 top 4.2 times the molar quantity of 30 to 37% hydrochloric acid and 1.9 to 2.1 times the molar quantity of 50 to 35% hydrogen peroxide, to act at 5 to 50.degree. C. on 1 mole of hydroquinone in at least 12 times the molar quantity of 30 to 37% hydrochloric acid, then heating the resulting suspension, which essentially contains 2,5-dichlorohydroquinone, to 45 to 55.degree. C. and again causing to act on it, at 50 to 95.degree. C., 3.8 to 4.2 times the molar quantity of 30 to 37% hydrochloric acid and 1.9 to 2.1 times the molar quantity of 50 to 35% hydrogen peroxide, in each case based on the hydroquinone used, and finally adding to the suspension, which is now essentially composed of trichloro-1,4-benzoquinone, 1.9 to 2.1 times the molar quantity of hydrochloric acid of the said concentration range, and 0.95 to 1.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: September 29, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Arndt, Theodor Papenfuhs
  • Patent number: 5151291
    Abstract: Glycerides of eicosapentaenoic acid (EPA) and other higher fatty acids, which contain high levels of EPA and docosahexaenoic acid. These glycerides are incorporated in oils and fats products such as margarine, shortening, mayonnaise, butter, dressing or edible oil.
    Type: Grant
    Filed: January 16, 1990
    Date of Patent: September 29, 1992
    Assignees: Nisshin Flour Milling Co., Ltd., Tsukishima Foods Co., Ltd.
    Inventors: Shigeru Tokairin, Tetsuo Nishimaki
  • Patent number: 5151548
    Abstract: Benzene derivatives of the general formula ##STR1## where Hal is halogen, R.sup.1 is a hydrocarbon radical of 1 to 18 carbon atoms, R.sup.2 is hydrogen or alkyl of 1 to 6 carbon atoms and X is hydrogen or halogen, are prepared by a process in which a toluene derivative of the general formula ##STR2## is electrochemically oxidized in the presence of an acid of the formula R.sup.2 --COOH (III). Novel benzene derivatives of the general formula ##STR3## where R.sup.3 is hydrogen or an R.sup.2 --CO-- radical but R.sup.1 cannot be methyl if X is hydrogen, and of the general formula ##STR4## where R.sup.4 is a branched or cyclic alkyl radical of 3 to 12 carbon atoms, but R.sup.4 cannot be isopropyl if X is hydrogen. The compounds of formulas IV and VI are intermediates for crop protecting agents, e.g. pyrethroids.
    Type: Grant
    Filed: June 12, 1989
    Date of Patent: September 29, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Dieter Hermeling, Dieter Degner, Albrecht Harreus, Norbert Goetz, Jochen Wild, Hans Theobald, Bernd Wolf
  • Patent number: 5149711
    Abstract: A 2-cyclopentenone derivative represented by the following formula ##STR1## wherein R.sup.1 represents an alkyl group having 1 to 10 carbon atoms which may be substituted by a substituted or unsubstituted phenyl or phenoxy group, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are identical or different and each represents a hydrogen atom or a lower alkanoyl group, and the wavy line shows that the bonded state of the double bond is E or Z.This compound is useful for treating, for instance, malignant tumors.
    Type: Grant
    Filed: March 7, 1989
    Date of Patent: September 22, 1992
    Assignee: Teijin Limited
    Inventors: Atsuo Hazato, Seizi Kurozumi
  • Patent number: 5149849
    Abstract: Disclosed is a process for the preparation of quinhydrones by the catalytic oxidation of aromatic diols with a peroxide in the presence of a catalyst system comprising a cerium carboxylate and a cupric carboxylate.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: September 22, 1992
    Inventors: Michael Bellas, Yeong-Jen Kuo, Fred H. Rash
  • Patent number: 5149856
    Abstract: Aromatic and aliphatic-aromatic carbonic acid diesters can be obtained by transesterification of carbonic acid diesters containing aliphatic ester groups if polymeric hydroxystannoxanes are employed as catalysts.
    Type: Grant
    Filed: February 20, 1991
    Date of Patent: September 22, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Norbert Schon, Hans-Josef Buysch, Wolfgang Ebert
  • Patent number: 5149862
    Abstract: A process for polymerizing tetrahydrofuran to produce polytetramethylene ether glycol or ester-capped polytetramethylene ether glycol is disclosed. The reaction mass is carried out at 10.degree. to 80.degree. C. and preferably 20.degree. to 60.degree. C. In a preferred aspect of the invention, a mixture of acetic anhydride and acetic acid is present in the reaction mixture.
    Type: Grant
    Filed: February 26, 1991
    Date of Patent: September 22, 1992
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Suriyanarayan Dorai, Melvin C. Baker, James A. Schultz
  • Patent number: 5149850
    Abstract: A process for the production of high-purity tetrachloro-1,4-benzoquinone by the action of chlorine and hydrochloric acid on hydroquinone which comprises causing 1.9 to 2.1 times the molar quantity of gaseous chlorine to act at temperatures from 5.degree. to 15.degree. C. on 1 mol of hydroquinone in 6 to 7 times the molar quantity of 30 to 37% hydrochloric acid, then diluting the resulting suspension, essentially containing 2,5-dichlorohydroquinone, with 2 to 3 parts of water, relative to hydroquinone employed, and initially warming to a temperature from 20.degree. to 30.degree. C., subsequently introducing 1.9 to 2.1 times the molar quantity of chlorine gas in an air atmosphere while raising the temperature to 90.degree.-100.degree. C. with simultaneous dilution with 3.5 to 4.5 parts of water, relative to hydroquinone employed, and finally introducing 1 to 2 times the molar quantity of gaseous chlorine, relative to hydroquinone employed, at temperatures from 100.degree. to 115.degree. C.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: September 22, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Arndt, Theodor Papenfuhs
  • Patent number: 5149852
    Abstract: This invention provides a process for concentration and separation of an eicosapentaenoic acid ester comprising:(1) a step in which a solution, in a nonpolar solvent, of a mixture of fatty acid esters containing an eicosapentaenoic acid ester is allowed to contact with a zeolite, so as to allow said eicosapentaenoic ester to be adsorbed on said zeolite;(2) a step in which said zeolite is allowed to contact with a nonpolar solvent, so as to desorb impurities; and(3) a step in which said zeolite is allowed to contact with a polar solvent, so as to allow said eicosapentaenoic acid ester to be desorbed.This process makes it possible to obtain a highly pure eicosapentaenoic acid ester on a commercial scale.
    Type: Grant
    Filed: March 27, 1991
    Date of Patent: September 22, 1992
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Makoto Arai, Hideki Fukuda
  • Patent number: 5149861
    Abstract: Trialkylamines and methyl formate are recovered from reaction mixtures obtained in the preparation of trimethylolalkanes by reaction of n-alkanals with from 2.2 to 4.5 moles of formaldehyde in aqueous solution in the presence of from 0.6 to 3 mole of trialkylamine, each quantity based on 1 mole of alkanal, and subsequent hydrogenation in a process wherein the crude reaction mixturea) is heated to from 100.degree. to 200.degree. C.
    Type: Grant
    Filed: March 1, 1991
    Date of Patent: September 22, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Franz Merger, Peter Hettinger, Leopold Hupfer, Juergen Paetsch, Heribert Deck, Heinz Auer, Erwin Brunner
  • Patent number: 5146009
    Abstract: According to the process of this invention, alcohols are recovered from aqueous acid solution by permeation of the alcohol through an organic-acid modified polymer membrane. An improved process for the manufacture of alcohols by acid absorption of olefins is also disclosed, the improvement residing in the use of an organic-acid modified polymer membrane to selectively permeate alcohols from the concentrated aqueous strong acid solution thereof co-produced in their synthesis from olefins.
    Type: Grant
    Filed: March 13, 1989
    Date of Patent: September 8, 1992
    Assignee: Exxon Chemicals Patents Inc.
    Inventors: Abraham D. Cohen, William D. Diana, James J. Baiel
  • Patent number: 5145989
    Abstract: Black acid or the sulfuric acid residue obtained in the manufacture of ethyl acrylate by reaction of ethylene and acrylic acid in the presence of sulfuric acid is heated and distilled in the presence of a solvent for recovery of acrylic acid and ethyl acrylate.
    Type: Grant
    Filed: July 14, 1987
    Date of Patent: September 8, 1992
    Assignee: Hoechst Celanese Corporation
    Inventors: Edward F. Dougherty, Paul James L.