Patents Examined by William A. Teol, Jr.
  • Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
    Patent number: 4804752
    Abstract: New syn-isomers of 3-cephem-4-carboxylic acids having anti-bacterial activities, processes for preparation thereof, pharmaceutical compositions thereof, with the acids being substituted at the 3 position with acyloxymethyl, hydroxymethyl, formyl or heterocyclic thiomethyl groups and at the 7 position with alkoxyiminoacetamido substituted with substituted phenyl or substituted thiazolyl.
    Type: Grant
    Filed: August 22, 1983
    Date of Patent: February 14, 1989
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Takao Takaya, Takashi Masugi, Hisashi Takasugi, Hiromu Kochi
  • Cephalosporin esters, their production and use
    Patent number: 4729992
    Abstract: A compound of the formula: ##STR1## or a pharmaceutical acceptable salt thereof, processes for preparing the same and a pharmaceutical composition containing the compound or the salt thereof mentioned above are provided. The compound has antibiotic activity and has improved absorbability.
    Type: Grant
    Filed: April 19, 1985
    Date of Patent: March 8, 1988
    Assignee: Tatsuo Chemical Ind., Ltd.
    Inventors: Tatsuo Nishimura, Yoshinobu Yoshimura, Mitsuo Numata
  • N-(chlorocarbonyloxy)-5-norbornene-2,3-dicarboximide, process for its production and its use
    Patent number: 4714768
    Abstract: A new compound is disclosed, N-(chlorocarbonyloxy-5-norbornene-2,3-dicarboximide I, in addition to processes for its production and employment of the compound as starting product for the manufacture of non-symmetrical carbonate, urethane-protected amino acid or peptide, activated carrier and carrier-ligand-complexes. The new compound is reacted with alcohols as well as with hydroxyl-group-containing or amino-group-containing polymers.
    Type: Grant
    Filed: August 27, 1984
    Date of Patent: December 22, 1987
    Assignee: Akademie Der Wissenschaften Der DDR
    Inventors: Peter Henklein, Manfred Becker, Werner Buttner, Fritz Loth, Horts Dautzenberg, Klaus Forner, Rudolf Dolling, Karl-Heinz Graul, Wolf-Rainer Halatsch, Christian Rupprich
  • Phenylpiperazine phosphonates
    Patent number: 4704382
    Abstract: The invention relates to compounds of the formula: ##STR1## which are useful cardiovascular agents.
    Type: Grant
    Filed: July 8, 1986
    Date of Patent: November 3, 1987
    Assignee: G. D. Searle & Co.
    Inventors: Robert J. Chorvat, Kerry W. Fowler, James P. Snyder