Patents Examined by William Craigo
  • Tesofensine and beta blocker combination formulations
    Patent number: 10537551
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: January 21, 2020
    Assignee: Saniona A/S
    Inventors: Peter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
  • Intrauterine delivery system for contraception
    Patent number: 10532025
    Abstract: The invention relates to a method for contraception and for reducing menstrual problems and inducing amenorrhea, wherein an intrauterine delivery device is used for the controlled release of a combination of progestogen or a drug having a progestogenic activity and at least one therapeutically active substance capable of preventing or suppressing abnormal and/or irregular endometrial bleeding over a prolonged period of time.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: January 14, 2020
    Assignee: Bayer Oy
    Inventors: Bernd Duesterberg, Manja Ahola, Jyrki Pihlaja, Heikki Lyytikäinen, Harri Jukarainen, Satu Kleemola, Tero Parkatti, Tuula Valo, Ina Gröticke, Bernhard Lindenthal, Ulrike Fuhrmann
  • Embolization device constructed from expansile polymer
    Patent number: 10499925
    Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: December 10, 2019
    Assignee: MicroVention, Inc.
    Inventors: Gregory M. Cruise, Michael Constant, Terrance Tran, Joseph Gulachenski
  • Embolization particulates for occluding a blood vessel
    Patent number: 10456235
    Abstract: Injectable embolization particulates (e.g., particles, microstructures, beads) employed in embolization procedures, for facilitating blood vessel occlusion. Exemplary embolization particulates for occluding a blood vessel include a plurality of embolization beads, each bead having a plurality of outwardly protruding portions, wherein, upon a first one and a second one of the beads accumulating against a boundary of the blood vessel, protruding portions of the first bead are configured to intermesh with protruding portions of the second bead, so as to occlude the blood vessel. Also disclosed are compositions of embolization particulates including a plurality of shaped embolization beads, and methods for embolizing or occluding a blood vessel using embolization particulates or compositions thereof.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: October 29, 2019
    Assignee: ACCURATE MEDICAL THERAPEUTICS LTD.
    Inventors: Michael Gabriel Tal, Eran Miller
  • Polymers for reversing heparin-based anticoagulation
    Patent number: 10441606
    Abstract: Embodiments presented herein relate to various polymers. Some of the polymer embodiments are heparin binding polymers. Some embodiments of the heparin binding polymers can be employed to bind to heparin for methods such as separating, purifying, removing, and/or isolating heparin and heparin like molecules.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: October 15, 2019
    Assignee: University of British Columbia
    Inventors: Jayachandran N. Kizhakkedathu, Rajesh A. Shenoi, Cedric J. Carter, Donald E. Brooks
  • Dietary supplement formulations
    Patent number: 10434087
    Abstract: Dietary supplement compositions directed to men and women and to the maintenance and improvement of human physiology, including weight, skin, hair, and general organ function and sexual health.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: October 8, 2019
    Assignee: SERENDIPITY TECHNOLOGIES LLC.
    Inventor: Amen Dhyllon
  • Hemostatic devices and methods of use
    Patent number: 10420864
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a first component having a first substrate and a second component having a second substrate. The second component is positioned within the first component. One of the first and second substrates includes a hemostatic agent and the other of the first and second substrates includes an active pharmaceutical ingredient. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: September 24, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie S. Soskin, Franklin R. Mansfield, Kai R. Worrell, Charlie Wood
  • Organic hair formulation and treatment
    Patent number: 10420962
    Abstract: A leave in organic hair treatment to stimulate hair growth and reduce sebum on scalp enabling the user to apply every 12 hours without the inconvenience of build up, greasy scalp or having to wash their hair. Also, an organic hair treatment for hair growth that can be formulated separately as a shampoo composition suitable for simultaneously cleansing and conditioning human hair, comprising in combination natural and organic sourced products. Also, an organic hair treatment for hair growth that can be formulated separately as a conditioner. Also, an organic hair treatment gel for hair growth that can be formulated separately as a hair gel. Also, an organic eyelash treatment for lash growth that can be formulated separately as an eyelash conditioning treatment.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: September 24, 2019
    Inventor: Sarah Holmes
  • Humidity tolerant carbon dioxide generator for arthropod trap and method of using same
    Patent number: 10420345
    Abstract: The present invention provides a humidity tolerant CO2 generator that operates in combination with an arthropod trap. The CO2 generator comprises a means for controllably adding solid pellets to an aqueous acid solution, and optionally includes a sound-based counting system for counting the number of pellets dispensed from a feeder reservoir and into a reaction chamber. The invention also provides a method of using the same.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: September 24, 2019
    Assignee: TDA Research, Inc.
    Inventors: Brady Clapsaddle, Joe Fredrickson, William Bell, Trevor Haanstad, Jeff Martin
  • Rehydration of micronized tecovirmimat monohydrate
    Patent number: 10406103
    Abstract: Disclosed are methods for hydration of ST-246 particles comprising exposing said particles to moisture by conveying volumes of air containing moisture.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: September 10, 2019
    Assignee: Siga Technologies Inc.
    Inventors: Shanthakumar R. Tyavanagimatt, Matthew Reeves, N K Peter Samuel, Steven Priebe, Ying Tan, Dennis E. Hruby
  • Thyroid hormone oral dosage forms and methods of using the same
    Patent number: 10406108
    Abstract: Novel thyroid hormone oral dosage forms and methods of making and using the thyroid hormone oral dosage forms are disclosed.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: September 10, 2019
    Assignee: GENUS LIFESCIENCES INC.
    Inventors: Shivaji Phadke, Vaishnavi Parikh
  • Disinfectant formulation
    Patent number: 10405544
    Abstract: An aqueous disinfectant formulation comprising at least one phenolic compound of natural origin; a surfactant sufficient to form a solution or dispersion of the essential oil in an aqueous carrier; a solvent, and sufficient water to make 100 weight percent is described herein.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: September 10, 2019
    Inventors: Francois Daigle, Ann Letellier, Sylvain Quessy
  • Process for the preparation of bio-organic coated gold and silver nanoparticles using blue light
    Patent number: 10369626
    Abstract: The present invention relates to a process which uses blue light to form bio-organic coated silver and gold nanoparticles for various applications. The present invention particularly relates to increasing the rates of reaction and widening the scope of tethering a range of biomolecules on the metal nanoparticles. The examples demonstrate that the biomolecules immobilized on the nanoparticles still retain many aspects of their structural elements which allow them to bind to their native binding partners and/or retain structural epitopes which allow them to be identified by antibodies specific to them, thus opening up scope of using such coated nanoparticles for functionalized and specific applications.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: August 6, 2019
    Assignee: Council of Scientific & Industrail Research
    Inventors: Ashish, Yogendra Singh Rathore, Nagesh Peddada, Kunzes Dolma, Renu Garg
  • Virus-PCION complex having enhanced antitumor effect by using electromagnetic field
    Patent number: 10357564
    Abstract: The present disclosure relates to a composition for transduction of a virus in a cell by using a crosslinked product of PEGylated magnetic nanoparticles and catechol grafted poly-L-lysine by application of an external magnetic field. When the composition is used, a virus may be delivered into cells more rapidly and efficiently than in intracellular uptake of a virus by CAR-mediated endocytosis.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: July 23, 2019
    Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
    Inventors: Chae Ok Yun, Joung-Woo Choi
  • Stable amorphous calcium carbonate comprising synthetic phosphorylated peptides
    Patent number: 10328100
    Abstract: Provided are compositions containing amorphous calcium carbonate (ACC), and at least one phosphorylated peptide which stabilizes the amorphous form of said calcium carbonate. Particularly, the peptide can be selected from crustacean proteins, also provided by the invention, namely GAP65, GAP22, GAP21, and GAP12 (also indicated herein as GAP10). The compositions are useful in pharmaceutical and nutraceutical formulations.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: June 25, 2019
    Assignee: AMORPHICAL LTD.
    Inventors: Shmuel Bentov, Amir Sagi, Amir Berman, Assaf Shechter
  • Rapamycin for the treatment of lymphangioleiomyomatosis
    Patent number: 10307370
    Abstract: The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods comprise administering to the subject via inhalation an aerosol composition comprising rapamycin or a prodrug or derivative (including analog) thereof.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: June 4, 2019
    Assignee: AI Therapeutics, Inc.
    Inventors: Henri Lichenstein, Jonathan M. Rothberg, Thomas Armer, Lawrence S. Melvin, Jr.
  • Methods and devices for conduit occlusion
    Patent number: 10292732
    Abstract: The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of means for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable material that supports tissue ingrowth that eventually replaces the material leaving little or no original material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: May 21, 2019
    Assignee: Femasys, Inc.
    Inventors: Kathy Lee-Sepsick, Lani L. L. Paxton, Jeffrey A. Marcus, Stephen N. Williams
  • Therapeutic agents for reducing parathyroid hormone levels
    Patent number: 10280198
    Abstract: Compounds having activity for lowering parathyroid hormone levels are described. In one embodiment, the compounds are comprised of a contiguous sequence of subunits, X1-X2-X3-X4-X5-X6-X7, wherein the X1 subunit comprises a thiol-containing moiety and the distribution of charge on the X2-X7 subunits provides the desired activity. Methods of using the compounds for treating hyperparathyroidism, bone disease and/or hypercalcemic disorders are also described, and in particular, methods for lowering plasma PTH and serum calcium are provided. The compounds can be used to treat subjects having, for example: primary, secondary or tertiary hyperparathyroidism; hypercalcemia of malignancy; metastatic bone disease; or osteoporosis.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: May 7, 2019
    Assignee: KAI PHARMACEUTICALS, INC.
    Inventors: Felix Karim, Amos Baruch, Derek Maclean, Kanad Das, Qun Yin
  • Method for preparing nanolipids with encapsulated alcohol
    Patent number: 10266800
    Abstract: A method for preparing ethanol-containing nanolipid particles, which can be used in food products, frozen desserts, or beverages. The method comprises nanolipidic vehicles in which ethanol-containing substances are encapsulated, said ethanol-containing nanolipidic vehicles can be combined with food products, desserts or beverage ingredients including those that are subsequently frozen. The food product, dessert or beverage can remain in a frozen state during consumption by an individual. A composition comprising ethanol-containing nanolipid particles, which can be used in food products, frozen desserts, or beverages.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: April 23, 2019
    Assignee: NuVessl, Inc
    Inventor: Michael W. Fountain
  • Antiperspirant aerosol compositions having reduced residue build-up
    Patent number: 10265250
    Abstract: The present invention relates to antiperspirant cosmetic agents in the form of an aerosol, which comprise a combination of a specific aluminum salt with at least one non-volatile ester and at least one volatile silicone compound. The aforementioned combination results in reduced residue build-up and improved cosmetic properties, and in particular in an improved dryness sensation on the skin. These agents furthermore have an outstanding antiperspirant action. The present invention further relates to a method for preventing and/or reducing perspiration of the body, using the cosmetic agent according to the invention, and to the use of the aforementioned combination of propellant-containing cosmetic agents.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: April 23, 2019
    Assignee: Henkel AG & Co. KGaA
    Inventors: Thomas Doering, Sandra Mausberg