Abstract: A system and method for automated collection and analysis of patient information retrieved from a medical device adapted to be implanted in a patient for remote patient care is described. A set of collected measures is periodically received from the medical device adapted to be implanted over a communications link which is interfaced to a network server. The collected measures set includes individual measures which each relate to patient information recorded by the medical device adapted to be implanted for an individual patient. The collected measures set is stored into a patient care record for the individual patient within a database server organized to store one or more patient care records. Each patient care record includes a plurality of the collected measures sets. One or more of the collected measures sets in the patient care record for the individual patient is analyzed relative to one or more other collected measures sets stored in the database server to determine a patient status indicator.

Abstract: An apparatus and method for adjunct (add-on) therapy of depression, migraine, neuropsychiatric disorders, partial complex epilepsy, generalized epilepsy and involuntary movement disorders comprises an implantable lead-receiver, and an external stimulator having controlling circuitry, a power source, and a coil to inductively couple the stimulator to the lead-receiver. The external stimulator emits electrical pulses to stimulate a cranial nerve such as the left vagus nerve according to a predetermined program. In a second mode of operation, an operator may manually override the predetermined sequence of stimulation.

Abstract: A kit of elements including an ultrasonic generator, transducers with connecting cables, and a means for locating the transducers over areas of the body containing cartilage, is provided with the surgical instruments for post-surgical application to ultrasonically stimulate the cartilage growth, thus relieving the effects of surgical intervention.

Abstract: An implantable device incorporating an acoustic transducer allows information and alerts to be communicated from the device to a patient. Sounds, including but not limited to buzzes, tones, sequences of tones, combinations of tones, complex sounds, and segments of reproduced or simulated human speech, are transmitted from an intracranially implanted portion of the device via bone conduction to the patient's ears, particularly the inner ears. In the disclosed embodiment, the acoustic transducer is used in cooperation with an implantable closed-loop system for the treatment of certain neurological disorders such as epilepsy, migraine headaches and Parkinson's disease, to warn the patient of an imminent seizure or other episode, to provide information to the patient on the state of the implantable apparatus, and to provide reminders and other information to the patient.

Abstract: Described is a data processing unit for the telemetric adjustment of an implant and for telemetric communication between the implant and a data device. The data device comprises a control unit for processing the data entered, a memory unit for saving the data supplied, an entry unit for entry of data, a display unit for display of data, a telemetry unit for transfer of data to the implant or vice versa; and at least one reading device to read and/or write on a first and second data carrier, whereby, on the first data carrier, one can store the status data transferred to the implant, and, on the second data carrier, the administrative data pertaining to the implant.

Abstract: Disclosed are techniques for therapeutically treating peripheral vascular disease. A sensor is implemented for sensing the extent of blood flow in a patient's limb or ischemic pain and generating a corresponding sensor signal. The signal is processed to determine the level of spinal cord stimulation or peripheral nerve stimulation to be applied. This information is provided to a signal generator which thereby provides electrical stimulation energy to one or more stimulation leads. Stimulation of the spinal cord, peripheral nerve or neural tissue ganglia thereby improves blood flow, helps restore tissue health and reduces the extent of ischemic pain in the limbs of a PVD patient or organs of other patients. Stimulation may be adjusted automatically to account for changing conditions of the patient throughout the day.

Abstract: It is important in cardiac pacing devices and systems to achieve efficient power utilization and conservation to extend the life of the battery cells, thereby extending the intervals between invasive medical procedures to replace components in the cardiac pacing system. A device and method are provided. The cardiac pacing device comprises a battery, a discrete time switched capacitor pacing power supply comprising a charge transfer capacitor bank comprising at least two capacitors, and a pace output supply capacitor which can discharge current to the tissue of a patient. A pacing supply design has a multiplicity of battery voltage multiplication factors and operating frequency settings. The pacing supply, voltage multiplier settings and operating frequency are automatically adjusted to compensate for changing pace output settings, load, cardiac cycle rate, and/or battery condition.

Abstract: A cardiac rhythm management system includes an atrial pacing preference (APP) filter for promoting atrial pacing. The APP filter includes an infinite impulse response (IIR) or other filter that controls the timing of delivery of atrial pacing pulses. The atrial pacing pulses are delivered at an APP-indicated pacing rate that is typically at a small amount above the intrinsic atrial heart rate. For sensed beats, the APP indicated rate is increased until it becomes slightly faster than the intrinsic atrial heart rate. The APP-indicated pacing rate is then gradually decreased to search for the underlying intrinsic atrial heart rate. Then, after a sensed atrial beat, the APP filter again increases the pacing rate until it becomes faster than the intrinsic atrial rate by a small amount. As a result, most atrial heart beats are paced, rather than sensed. This decreases the likelihood of the occurrence of an atrial tachyarrhythima, such as atrial fibrillation.

Abstract: A system for measuring and analyzing CPR parameters for use with and by an external defibrillator, where a pressure sensitive electrode is connected to a defibrillator, in addition to the standard electrodes of the defibrillator. The information from the pressure sensitive electrode, together with information derived from modulation of the impedance of the thorax, measured by the defibrillator, describes the quality of the CPR performed, and is used to generate voice messages that increase the quality and the effectiveness of the CPR. The defibrillator may in addition be equipped with a transmission device that sets up a radio connection with an emergency center. The emergency center is equipped with a display unit that shows the activities at the resuscitation site.

Abstract: A method and apparatus for monitoring syncope, and having available for use an electrical cardiac output forcing (ECOF) back up. An implantable device, including an ECOF back up, for recording the electrical activity within a human heart is provided. The device includes a power supply for operating the device and for providing the necessary output forcing signals. A monitoring or detection device is provided connected to the power supply. Electrodes are provided to electrically connect the power supply and the detection device to a patient's heart. A memory device is also provided connected to the detection device for recording electrical activity and/or blood pressure data of the patient's heart. The memory device may be comprised of a short term loop buffer for continuously recording the electrical data from the patient's heart and a long term storage buffer. The short term loop may be of a desired size, for example, capable of storing from 1-30 minutes of data before overriding occurs.

Abstract: A system is provided for remotely monitoring fetal status parameters. Status parameters are sampled from patient sensors and are processed and stored in a medical facility data management system. A general purpose data presentation application, such as a browser, is employed on a client side to access the data via a network, such as the Internet. Support software is called upon to format user-viewable pages and to insert data transmitted from the medical facility for remote viewing. The technique is particularly well suited to monitoring of a variety of parameters at various sampling rates for remote medical evaluation, such as in obstetrics applications.

Abstract: A non-invasive method of treating, controlling or preventing medical, psychiatric or neurological disorders is provided using transcutaneous electrical stimulation. A plurality of stimulation frequency parameters are used ranging from a relatively high frequency, for example about 40,000 Hertz, to a relatively low frequency, for example about 250 Hertz. The entirety of frequency parameters may be administered at each of a plurality of stimulation intensity levels. In particular, stimulating may begin at a first highest frequency parameter and a first lowest intensity parameter with the stimulation frequency parameter incrementally decreasing to the lowest frequency parameter. Then the frequency parameter is returned to the highest frequency parameter, and the intensity parameter increased to a next higher intensity parameter, and again stimulating through the plurality of frequency parameters from the highest frequency to the lowest frequency.

Abstract: A cardiac rhythm management system includes an atrial pacing preference (APP) filter for promoting atrial pacing. The APP filter includes an infinite impulse response (IIR) or other filter that controls the timing of delivery of atrial pacing pulses. The atrial pacing pulses are delivered at an APP-indicated pacing rate that is typically at a small amount above the intrinsic atrial heart rate. For sensed beats, the APP indicated rate is increased until it becomes slightly faster than the intrinsic atrial heart rate. The APP-indicated pacing rate is then gradually decreased to search for the underlying intrinsic atrial heart rate. Then, after a sensed atrial beat, the APP filter again increases the pacing rate until it becomes faster than the intrinsic atrial rate by a small amount. As a result, most atrial heart beats are paced, rather than sensed. This decreases the likelihood of the occurrence of an atrial tachyarrhythmia, such as atrial fibrillation.

Abstract: An inflow conduit assembly for conducting blood from a ventricle to a Ventricular Assistance Device (VAD) is provided. The assembly includes a rigid tube including an angled heart engaging end for insertion into a ventricle. The angled heart engaging end defines a long side for placement adjacent a heart septum. The tube includes an orifice end for attachment to the VAD, and the inflow conduit assembly further includes a coupling for attaching the orifice end of the tube to the VAD. The coupling is movable between a rotatable position wherein the tube is rotatable relative to the VAD, and a locked position wherein the tube is immobile relative to the VAD.

Abstract: A method for generating a synthesis echocardiographic image comprises first obtaining, for a plurality of pathologically similar reference hearts, a reference echocardiographic image of each reference heart at end-systole and at end-diastole. Next, the coupled epicardial and endocardial borders are identified in each echocardiographic image. An epicardial/endocardial border pair is then modeled from the identified borders. The method then locates a plurality of predetermined features in the reference echocardiographic images. The predetermined features are then located in the subject echocardiographic image from the location of the predetermined features in the reference echocardiographic images. The modeled epicardial/endocardial border pair is then mapped onto the subject echocardiographic image relative to the location of the predetermined features in the subject echocardiographic image.

Abstract: An optically controllable microelectrode array for stimulating cells within a tissue is disclosed. The array comprises a substrate having a surface. The substrate is adapted to be placed on the tissue with the surface adjoining the cells. The substrate further comprises a plurality of electrodes on the surface in contact with the cells for stimulating the cells. The electrodes are dimensioned such that a first surface area on the electrodes in contact with the cells is essentially smaller than a second surface area on the cells in which the cells may be contacted by the electrodes. An electrical stimulus is exerted from the electrodes to the cells under the control of light impinging on the tissue.

Abstract: An electrotherapy apparatus, such as a defibrillator, includes a connecting mechanism coupled between an energy source and electrodes. The connecting mechanism allows selective coupling of the energy source to the electrodes. The energy source includes a capacitor and a high voltage power supply for charging the capacitor. The electrotherapy apparatus further includes a waveform measuring device for measuring a patient ECG waveform. The electrotherapy apparatus also includes a controller coupled to the connecting mechanism, the energy source, and the waveform measuring device. The controller actuates the connecting mechanism to deliver a bi-phasic waveform to the patient. In addition, the controller analyzes the ECG waveform to detect when the patient is experiencing either course arrhythmia or fine arrhythmia.

Abstract: A medical lead adaptor that provides a rapid, secure, insulated connection of the lead connector end assembly of a cardiac lead having electrodes adapted to be placed in or on the body with an external medical device. The adaptor connector assembly is configured with an elongated receptacle to accept a bipolar, in-line, or a unipolar lead connector end sharing common dimensions. The elongated receptacle includes connector pin and ring receptacle contacts spaced apart from one another therein. In a preferred embodiment, an elongated slot that extends laterally of the elongated receptacle cooperates with a lock mechanism to allow the lateral insertion of the lead connector end assembly, with a stylet wire inserted into the cardiac lead body lumen, into the elongated receptacle. When inserted therein, the lead connector ring and/or pin are nested into contact with the ring and/or pin receptacle contacts and are held there by the lock mechanism.

Abstract: A system and method for using electrical stimulation of the vagus nerve to treat epilepsy with minimized or no effect on the heart. Treatment is carried out by an implantable signal generator, one or more implantable electrodes for electrically stimulating a predetermined stimulation site of the vagus nerve, and a sensor for sensing characteristics of the heart such as a heart rate. The heart rate information from the sensor can be used to determine whether the vagus nerve stimulation is adversely affecting the heart. Once threshold parameters are met, the vagus nerve stimulation may be stopped or adjusted. In an alternative embodiment, a modified pacemaker is used to maintain the heart in desired conditions during the vagus nerve stimulation. In yet another embodiment, a modified pacemaker having circuitry that determines whether a vagus nerve is being stimulated is used.

Abstract: Tripolar stimulation of the heart utilizes electrodes implanted in at least two locations in the heart. In a first case, for bi-atrial or bi-ventricular stimulation, electrodes are placed in an appropriate heart chamber and in a blood vessel of the heart. In a second case, electrodes are placed in two separate locations in the same chamber of the heart. In either case, one location is for performing unipolar stimulation (i.e., has electrodes of only a singular polarity), while the other location is for bipolar stimulation (i.e., has electrodes of both positive and negative polarities).