Abstract: A two part lens system. The first part is a ring-like supporting component that is implanted in the capsular bag following cataract surgery. The first component is a non-optical component and contains a pair of haptics for fixating the first component within the capsular bag. The second component is an optical component that contains all of the corrective optical power of the lens system. The second component has a pair of tabs for locking the second component within the first component.

Abstract: The present invention provides systems and methods for deploying implantable devices within the body. The delivery and deployment systems include at least one catheter or an assembly of catheters for selectively positioning the lumens of the implant to within target vessels. Various deployment and attachment mechanisms are provided for selectively deploying the implants.

Abstract: Disclosed is a modular femoral sizing guide which facilitates the selection and rotational orientation of a femoral prosthetic for a resected femur. The femoral sizing guide has a base which is coupled to the resected femur. An extension portion which is configured to have a pair of feet which are coupled to the posterior surface of the resected femur is rotatably coupled to the base portion. A superstructure having a pair of drilling guides and a stylus is slidably coupled to the base.

Abstract: The invention relates to an artificial intraocular lens consisting of a polymer material which permits a change of the optical properties of the artificial intraocular lens when exposed to light. This enables the lens to be exactly adjusted to the required visual acuity upon implantation thereof.

Abstract: An accommodating intraocular lens having an optic and portions extending from the optic radially outwards preferably with fixation devices at their distal ends, the optic designed such that it has a sharp posterior edge for 360 degrees of its perimeter and the lens designed such that the optic can move forward and backwards with constriction and relaxation of the ciliary muscle.

Abstract: An annuloplasty band comprising a sheath, and a generally arcuate stiffening element disposed within the sheath. The stiffening element extends from a first end to a second end, and preferably includes eyelets at its first and second ends adapted to receive sutures to secure the annuloplasty band to a valve annulus. The annuloplasty band preferably has a low profile (e.g., a thickness less than 3 mm). In embodiments intended for mitral valve repair, the eyelets are particularly adapted to receive sutures to secure the annuloplasty band to the antero-lateral trigone and postero-medial trigone. A holder and sizer device useful with the annuloplasty band are also provided.

Abstract: A fixation band has a tubular frame and a tube, wherein the tubular frame comprises longitudinally-extending members having a hook on its distal end and fixation means on its proximal end. The tubular frame preferably comprises a laterally-extending member for stabilization. The tube is positioned inside longitudinally-extending members and a sewing cuff is formed in the tube distal to the distalmost end of the longitudinally-extending members. A standard prosthetic valve can be secured to the fixation band by suturing the prosthetic valve's sewing cuff to the fixation band's sewing cuff and the prosthetic valve can be advanced to a valve seat. By pulling the tubular frame proximally, the hooks pass into surrounding tissue so that the fixation band and prosthetic valve are fixed against proximal movement. The fixation means then secure the fixation band to the surrounding tissue so that the prosthetic valve is fixed against distal movement.

Abstract: Valve repair apparatus and methods for ensuring proper coaptation and operation of the leaflets of a heart valve. Main aspects of the disclosure relate to devices including a support member configured for attachment to the heart valve annulus, a post extending from the support member away from the plane of the annulus and a connector coupled with the post and configured for attachment to at least one of the leaflets. The various embodiments may include a replacement heart valve connected with the support member for facilitating full replacement as opposed to near repair of an existing native heart valve. Various other devices include support structure and one or more posts connected to opposite sides of the support structure and extending from one side of the valve annulus to another to modify the shape of the annulus.

Abstract: A replacement heart valve apparatus. The heart valve apparatus includes a stent and a valve frame having a substantially cylindrical body defining a lumen. The valve frame includes a plurality of curved wire pairs attached to the substantially cylindrical body. Each curved wire pair includes an inner curved wire and an outer curved wire. The wire frame further having a plurality of leaflets. Each leaflet is attached to a respective inner curved wire and extends over a respective outer curved wire, so as to position the body of the leaflet within the lumen of the valve frame.

Abstract: A ureteral stent is designed to be placed within a patient's ureter to facilitate drainage from the patient's kidneys to the bladder. An elongated portion of the stent includes a length sufficient to extend substantially within the ureter from the kidney to the bladder, and the elongated portion defines a lumen extending therethrough. A retention portion extends from one end of the elongated portion and retains the position of the ureteral stent when placed substantially within the kidney. The retention portion includes an interior space that is in communication with the lumen within the elongated portion and has at least one opening for urine drainage. A flared portion extending from the other end of the elongated portion is positioned within the patient's bladder. The flared portion curves outward and includes an elastic member that maintains the shape of the flared portion when positioned within the bladder.

Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.

Abstract: An accommodative intra-ocular lens deformable between the unaccommodating and accommodating configurations upon the relaxation and contraction of the ciliary muscle. The lens anterior and posterior portions are substantially sealingly joined together about their peripheral edges and define a lens internal volume filled with a substantially incompressible lens internal fluid. Causing a variable internal fluid pressure exerted on the lens inner surfaces. The lens is configured such that radius of curvature of both the central and peripheral sections of the lens anterior portion will decrease upon an increase in internal fluid pressure and increase upon a decrease in internal fluid pressure.

Abstract: Methods and apparatus described herein may utilize activation of an SMP material to install medical devices with respect to a surgical site. Activation of the SMP material may be performed with the use of a triggering force and/or a constraint applied to the SMP material. Activation using a triggering force and/or a constraint may be used to create varied activation rates in an SMP material and may be combined with temperature or other activation stimuli to create the varied activation rates.

Abstract: The invention concerns an intraocular lens with negative spherical aberration and a method of determining the refractive power of intraocular lenses. In the environment of immersion medium the intraocular lens refracts an incoming wave with an elliptically oblongly curved wave front into an outgoing wave with a substantially spherical wave front.

Abstract: A vascular or endoluminal stent is adapted to be implanted in a vessel, duct or tract of a human body to maintain an open lumen. The stent includes a base layer of a biologically compatible metal. An intermediate metal particle layer of substantial greater radiopacity overlies the base layer, with particles bonded to the base layer and to each other to leave interstices therebetween as a repository for retaining and dispensing drugs or other agents for time release therefrom. The particles are composed primarily of a noble metal. Exposed surfaces of the particle layer are coated with ceramic-like iridium oxide or titanium nitrate, as a biocompatible material to inhibit irritation of tissue at the inner lining of the vessel when the stent is implanted.

Abstract: The invention provides a stent-graft system comprising a graft member and a stent having a connection end interconnected with the graft member and a free end opposed thereto. A belt retaining structure is provided at the stent free end. A belt is releasably retained in the belt retaining structure and is configured to constrain the stent free end independent of the stent connection end. A method of securing at least one end of a stent-graft within a vessel is also provided.

Abstract: A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.

Abstract: The present invention provides an endoprosthesis comprising a radially distensible, tubular stent comprising opposed open ends and a stent wall structure having opposed exterior and luminal surfaces; and a continuous and seamless ePTFE tubular covering having a node and fibril structure securably disposed to at least one of the stent surfaces, the graft covering comprising at least two laminated layers, wherein the laminated layers include at least one region where the laminated layers are not securely bonded; and the at least one region has a different bending flexibility from the tubular graft covering.

Abstract: An intraocular lens having a light-transmitting optic (32, 94a, 94b, 142, 148, 216) comprised of a synthetic light-refractive material (40, 102) operably coupled with a flexible optic positioning member (34, 62, 74, 84, 100, 150, 210) to refract light onto the retina in order to correct refractive errors in the eye (10). The refractive material has an index of refraction of from about 1.36 to 1.5 or higher. The optic positioning member (34, 62, 74, 84, 100, 150, 210) is constructed of a flexible synthetic resin material such as polymethylmethacrylate and permits focusing upon objects located near to and far from the viewer. The optic (32, 94a, 94b, 142, 148, 216) of the present invention possess greater refractive capability than optics conventionally used in IOL construction, and permits retinal receipt of the image being viewed in order to correct refractive errors.

Abstract: An accommodating intraocular lens, for use in an eye, is made from flexible, optionally elastic, bio-compatible lens body material surrounding a closed and sealed lens cavity which is filled with bio-compatible optical liquid, optionally a gel. The optical liquid has a refractive index sufficiently high to, in cooperation with the ciliary muscle, focus light, incident on the eye, on the retina, and to provide accommodation. The curvature of the front surface of the lens is deformable, by the pressure expressed by the ciliary body during the accommodative effort, thus to change the radius of curvature of the anterior body member and/or the posterior body member, thus providing smooth focusing, including from far distance in the relaxed state to near distance of less than 50 centimeters in the accommodative state.