Patents Examined by William. M. Moore
  • Process for preparing doxorubicin
    Patent number: 6210930
    Abstract: The present invention is directed to a process for improving daunorubicin and doxorubicin production by means of a recombinant microorganism in which a gene of daunorubicin metabolism is mutated. The mutated gene is preferably dnrU and/or dnrX.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: April 3, 2001
    Assignee: Pharmacia & Upjohn, S.P.A.
    Inventors: Silvia Filippini, Natalia Lomovskaya, Leonid Fonstein, Anna Luisa Colombo, C. Richard Hutchinson, Sharee L. Otten, Umberto Breme