Abstract: Methods, devices and systems for delivering light therapy to human or non-human animal subjects. Included are shapeable light therapy devices which are formable into different shapes suitable for delivery of therapeutic light to different regions of the subject's body and will retain the desired shape without a need for the use of a strap or other shape-retaining apparatus. Also included are light therapy devices that, in at least some modes of operation, deliver light that is not visible to the human eye and which include indicator(s) to indicate to a user and/or to the subject being treated when non-visible light is actually being emitted.

Abstract: An apparatus for treatment of soft tissue includes a source of radiation, a handpiece which is adapted to transmit radiation emitted from the source of radiation to a region of soft tissue, resulting in irradiated soft tissue, said handpiece being positioned adjacent to or in contact with said soft tissue region, a grid element adapted to hold at least one temperature sensor in contact with or embedded in said region of soft tissue, and a microprocessor, which converts a signal from the at least one temperature sensor into a measure of damage produced in at least two components of the irradiated soft tissue, said components comprising at least one normal tissue component and at least one malignant, hypertrophic, diseased, or unwanted component.

Abstract: Mouth guards having electrodes, sensors, and/or accelerometers for determining one or more physiological conditions of a subject. Processing circuitry receives the outputs of the electrodes, sensors, and/or accelerometers. Optionally, at least a portion of the processing circuitry can be positioned within a helmet that is worn by a subject. The mouth guard can optionally be tethered to the helmet.

Abstract: A method for generating cut surfaces in the cornea of an eye in order to correct ametropia using an apparatus. The method includes providing the apparatus including a laser unit, which focuses pulsed laser radiation into the cornea and moves the focused radiation in the cornea to generate cut surfaces, and a control unit, which controls the laser unit for generating cut surfaces. The method includes forming at least two mutually spaced apart cut surfaces as opening cuts by application of the pulsed laser radiation from the laser unit, each opening cut extending from an anterior corneal surface into the cornea and forming a further cut surface as a relieving cut by application of the pulsed laser radiation from the laser unit, which relieving cut extends from the anterior corneal surface into the cornea. The position and shape of the relieving cut is selected such that the relieving cut contributes to the correction of the ametropia of the eye.

Abstract: A non-invasive method for determining the tissue perfusion state in a patient, by measuring the variations in the skin CO2 pressure and in the perfusion index of the patient during the conducting of a localized hyperthermia test.

Abstract: Systems and methods of laser treatment of the intact crystalline lens to increase ionic transport of antioxidants in specific areas where flexural changes and transparency reduction come from lens aging. Microchannels created in patterns and grids placed strategically in the inner lens carry antioxidants from the source—the anterior and the epithelium—into areas scarce or void of transport mechanisms (and thus scarce of antioxidants). A variety of patterns are utilized to facilitate ions traveling along new pathways.

Abstract: A method, system and device for shortening hair with the method including generating a plurality of laser pulses overlapping in time; focusing the laser pulses into spatially separated focal spots having a peak power density at least equal to a first threshold at which a laser induced optical breakdown phenomenon occurs in the hair and below a second threshold at which a laser induced optical breakdown phenomenon occurs in skin. Generating the plurality of laser pulses includes an act of generating the plurality of laser pulses to reach the first characteristic threshold value after a start of each corresponding laser pulse in a time span of less than half of the pulse duration; and positioning the respective at least three focal spots into respective target positions within a single hair such that only one of the plurality of laser pulses occur in each of the at least three focal spots.

Abstract: According to an embodiment of the present application, there is provided a medical apparatus, including: a light source unit configured to be capable of emitting light including at least natural emission light, the light being guided into an optical probe; a first detecting unit configured to detect an intensity of light exiting from the light source unit; and a calculation unit configured to calculate to approximate to a non-linear function based on an intensity of light detected by the first detecting unit for calibration of the optical probe.

Abstract: The present disclosure is directed towards a medical instrument. The medical instrument includes a housing and an end effector assembly operably connected to the housing. The end effector assembly includes first and second jaw members each having a tissue contacting surface, at least one of the first and second jaw members movable between a first, spaced-apart position and a second proximate position, wherein in the second position, the jaw members cooperate to define a cavity configured to receive tissue between the jaw members. The end effector also includes at least one light-emitting element coupled to at least one of the first and second jaw members, the at least one light-emitting element adapted to deliver light energy to tissue grasped between the first and second jaw members to treat the tissue.

Abstract: A steerable laser probe may include an actuation structure, a nosecone fixed to the actuation structure by one or more links and one or more link pins, a flexible housing tube, and an optic fiber disposed in the flexible housing tube and the actuation structure. A compression of the actuation structure may be configured to gradually curve the flexible housing tube and the optic fiber. A decompression of the actuation structure may be configured to gradually straighten the flexible housing tube and the optic fiber.

Abstract: Described herein are devices, systems, and methods for delivering phototherapy to a subject. A phototherapy light engine is combined with other components to form a phototherapy system that provides phototherapy treatment to a subject. A phototherapy system may be implemented as a hand held system comprising the light engine that is configured to communicate with a remote computing device.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a plurality of actuation controls of the handle, a flexible housing tube having a flexible housing tube distal end and a flexible housing tube proximal end, and an optic fiber disposed within an inner bore of the handle and the flexible housing tube. An actuation of an actuation control of the plurality of actuation controls may gradually curve the flexible housing tube. A gradual curving of the flexible housing tube may gradually curve the optic fiber. An actuation of an actuation control of the plurality of actuation controls may gradually straighten the flexible housing tube. A gradual straightening of the flexible housing tube may gradually straighten the optic fiber.

Abstract: A steerable laser probe may include a handle, an actuation lever, an optic fiber, and a housing tube. The housing tube may have a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater than the first stiffness. The optic fiber may be disposed within the housing tube and within an inner bore of the handle. An actuation of the actuation lever about a pivot pin of the handle may gradually curve the optic fiber. An actuation of the actuation lever about the pivot pin of the handle may gradually straighten the optic fiber.

Abstract: A device that reduces subcutaneous adipose tissue using a matrix of LEDs to heat and destroy fat cells. The surface facing the patient's skin may be a plate of thermally conductive material such as copper or aluminum, with apertures for the LEDs. Fat reduction may be optimized using infrared LEDs with peak spectral power in the range of 920 nm to 950 nm. The device may include multiple light emitting sections connected with flexible couplings so that the device can conform to curved body shapes; treatment surfaces of individual sections may also be curved. Sections may include cooling mechanisms to cool both the LEDs and the plate facing the patient's skin, such as thermoelectric cooling elements and air or water circulation. A user interface may provide monitoring and control of treatment parameters. The device may incorporate ultraviolet LEDs to facilitate removal of an adhesive attaching the device to the patient.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a plurality of actuation controls of the handle, a housing tube having a housing tube distal end and a housing tube proximal end, and an optic fiber disposed within an inner bore of the handle and the housing tube. An actuation of an actuation control of the plurality of actuation controls may gradually curve the housing tube. A gradual curving of the housing tube may gradually curve the optic fiber. An actuation of an actuation control of the plurality of actuation controls may gradually straighten the housing tube. A gradual straightening of the housing tube may gradually straighten the optic fiber.

Abstract: A steerable laser probe may include a handle, an actuation mechanism of the handle, an optic fiber, and a housing tube. The housing tube may include a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater than the first stiffness. The optic fiber may be disposed within the housing tube and within an inner bore of the handle. A portion of the optic fiber may be fixed to an inner portion of the housing tube.

Abstract: A steerable laser probe may include a handle, an actuation structure of the handle, a housing tube, a flexible tube, an optic fiber, and a wire having a pre-formed curve. The flexible tube may be disposed within the housing tube wherein a distal end of the flexible tube projects out from a distal end of the housing tube. The optic fiber may be disposed within an inner bore of the handle, the housing tube, and the flexible tube. The wire may be disposed within the housing tube.

Abstract: A steerable laser probe may include a handle having a handle, a housing sleeve, a first portion of the housing sleeve having a first stiffness, a second portion of the housing sleeve having a second stiffness, an actuation control of the handle, an optic fiber disposed in an inner bore of the handle and the housing sleeve, and a shape memory wire having a pre-formed curve. An actuation of the actuation control may be configured to gradually curve the housing sleeve and the optic fiber. An actuation of the actuation control may be configured to gradually straighten the housing sleeve and the optic fiber.

Abstract: An apparatus for treating hemorrhoids including a first member having a proximal portion, a distal portion and a window formed therein to receive tissue. A third member is operably connected to the second member and movable between a first position and a second position, the third member having a clamping surface movable to the second position to provide a clamping force on tissue received through the window. Movement of the second member in a distal direction moves the third member in the distal direction toward the second position, the third member movable in a distal direction until such movement is limited due to contact and compression of tissue within the window, the second member continuing movement in the distal direction after movement of the third member in the distal direction has been limited.

Abstract: Systems and methods described herein relate to a sleep diagnostic system including a mattress assembly, a plurality of sensors, data acquisition circuitry, an input device, a sleep processor, and a display device. The mattress assembly may have a sleeping surface, and the plurality of sensors may be disposed within the mattress assembly below the sleeping surface. The sensors are configured to measure at least one sleep condition and output data signals indicative of the sleep condition. The sleep processor receives signals from both the sensors and one or more other input devices, and determines a sleep characteristic based upon these received signals. The display device, which includes circuitry and a graphical user interface, receives the sleep characteristic from the sleep processor and displays it to the user.