Patents Examined by William W. Moore, III
  • Bifunctional urokinase variants with improved fibrinolytic characteristics and thrombin inhibiting effect
    Patent number: 5747291
    Abstract: Bifunctional urokinase variants possessing improved fibrinolytic properties and thrombin inhibitory activities, plasmids used in the production of these polypeptides, as well as thrombolytic agents containing one of the bifunctional urokinase variants as active ingredient are described.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: May 5, 1998
    Assignee: Gruenenthal GmbH
    Inventors: Gerd J. Steffens, Stephan Wnendt, Johannes Schneider, Regina Heinzel-Wieland, Derek John Saunders