Abstract: A medical solution tubing useful in combination with medical solution packages and pouches includes an outer layer of polypropylene, ethylene propylene copolymer, or modified ethylene propylene copolymer; an intermediate layer comprising a polymeric elastomer, a blend of a low melt index EVA and a high melt index EVA, EnBA, or blends thereof, or a blend of an EVA-based polymeric adhesive and an elastomeric polyester; and an inner layer comprising EVA, a blend of a low melt index EVA and a high melt index EVA, EMA, EnBA, or blends thereof, or PVC.

Abstract: A coextruded packaging film has an outer and intermediate layer of fully hydrolyzed polyvinyl alcohol, partially hydrolyzed polyvinyl alcohol, or polyethylene oxide; and an inner layer comprising acid/acrylate copolymer, styrene maleic anhydride copolymer, ethylene acrylic acid copolymer, ionomer, cellulose, hydroxy propyl cellulose, polyether block amide copolymer, polyhydroxy butyric acid, polyhydroxy valeric acid, polyethylene oxide, polyester, copolyester, polyethyloxazoline, polyurethane, partially metal salt neutralized acid/acrylate copolymer, and a blend of acid/acrylate copolymer and ionomer. Fillers such as salt can optionally be added to one or more of the polymeric materials, prior to or during coextrusion of the film, to improve the processability of the film or to add a pigment to the film.

Abstract: Cosmetic skin care compositions containing cumic alcohol. The inventive compositions improve transglutaminase-1 and ceramide expression in skin cells, and enhance the cell uptake of glucose and ascorbic acid.

Abstract: A viscous gel for delivering minor effective homeopathic amount of zinc or another metal to the nasal membrane.

Abstract: A non-occlusive medication patch to be applied to the skin includes a porous self-supporting backing layer to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer with an exposed lower skin-contacting surface that forms a pressure-sensitive bond with the skin, and second, an upper internal portion which infiltrates the porous backing and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir.

Abstract: A composition in the form of an anhydrous emulsion having as a dispersed phase ascorbic acid dissolved in a nonaqueous polar organic solvent, and as the continous phase a nonaqueous nonpolar organic solvent, as well as a method for dissolving ascorbic acid.

Abstract: Dispersibility of a respirable powder, administrable by inhalation, is increased by including a pharmaceutically acceptable water-soluble polypeptide.

Abstract: A transdermal absorption preparation containing &agr;-form crystals of indomethacin in a vehicle. The present invention aims to provide an indomethacin-containing transdermal absorption preparation increased in the percutaneous absorption of indomethacin from the preparation, and improved in the stability of indomethacin in the preparation.

Abstract: White or colored pigments which do not suffer from color tone or hiding performances thereof even when the surface is moistened with water or oil, without spoiling coloring performance or hiding performance of the pigments themselves. These pigments are surface-coated with an inorganic compound having the refractive index of 1.8 or below. The inorganic compound is preferably silicon oxide, and the pigments are preferably inorganic pigments comprising titanium oxide, zinc oxide, or iron oxide. The cosmetics of the invention are blended the pigments therein.

Abstract: The present invention relates to the use of at least two compounds chosen from components having an a) anti-radical, b) anti-inflammatory and c) anti-allergic activity for the preparation of a composition exhibiting at least two of the a), b) and c) activities intended for the treatment of sensitive and/or allergic skin. It also relates to a process for the preparation of such compositions and to the compositions thus obtained.

Abstract: The present invention relates to compositions and methods for treating cell damage caused by reactive oxygen species in relation to a variety of skin disorders. More specifically, the present invention relates to the treatment skin disorders through the topical delivery of reactive oxygen metabolite production or release inhibiting compounds.

Abstract: A self dosing skin composition and method releases sun blocking agent or other active ingredient onto the skin of a user as a function of exposure to at least one environmental condition over time. The environmental condition is preferably exposure to sun light, in particular, harmful UV radiation. The composition includes a medium adapted to be spread onto the skin of a user and a reservoir defining at least one wall for containing at least one sun blocking or other agent. The reservoir is dispersed in the medium and the wall is designed and/or selected to deteriorate over time with exposure to the environmental condition or conditions, for releasing the agent into the medium and onto the skin. At least one agent is provided in the reservoir.

Abstract: The invention relates to a method of treating Attention Deficit Disorder (ADD) and Attention Deficit/Hyperactivity Disorder (ADHD) and compositions for topical application of methylphenidate comprising methylphenidate in a flexible, finite system wherein the methylphenidate is present in an amount sufficient to achieve substantially zero order kinetics for delivery to the skin or mucosa of a patient in need thereof over a period of time at least 10 hours.

Abstract: A viscous hydrogel composition, for use in a topical treatment of a skin condition involving dry or inflammed skin, comprising an antimicrobially active nitroimidazole drug, a water miscible alkylene glycol, a bydroxyalkyl cellulose gelling agent and water, buffered to have a physiologically acceptable pH and a method of making the same.

Abstract: Use of ascorbic acid derivatives of the formula I where the variables independently of one another have the following meanings: R1 is hydrogen, C1-C20-acyl, C1-Cl2-alkoxycarbonyl, C1-C12-alkyl, R2 is hydrogen, C1-C20-acyl, C1-Cl2-alkoxycarbonyl, C1-C12-alkyl, where R1 and R2, together with the oxygen atoms to which they are bonded and the carbon atoms bonded to the oxygen atoms, can form an unsubstituted or substituted heterocycle, R3 is hydrogen or a cation selected from the group consisting of NH4+, alkali metal and alkaline earth metal cations, R4 is C1-C12-alkoxycarbonyl, for cosmetic and pharmaceutical preparations is described.

Abstract: Disclosed is a process for preparing water-in-oil type emulsion cosmetic compositions containing L-ascorbic acid. The use of 2-hydroxypropyl cyclodextrin and a water-in-oil type emulsion allow L-ascorbic acid itself to be preserved for a lengthy period of time with high functional maintenance. Even after being stored for a significant period of time, the water-in-oil type emulsion cosmetic compositions do not exhibit discoloration nor give out offensive odor nor show the separation of cosmetic ingredients. In addition, the cosmetic compositions keep L-ascorbic acid high in the effective whitening activity, such as melanin reduction and inhibitory activity against tyrosinase.

Abstract: The present invention relates to a deodorant composition, in particular a cosmetic composition, comprising, as odor-absorbing agent, at least one water-soluble zinc salt, and preferably zinc pyrrolidonecarboxylate, to the use of the composition for the manufacture of cosmetic products intended for human topical application, in particular deodorants, to a process for treating human axillary smells, and to the use of a water-soluble zinc salt as, preferably sole, an odor-absorbing agent in a deodorant composition. The composition is particularly intended for formulations comprising an aqueous phase: aqueous lotions, emulsions and preferably water-in-silicone emulsions.

Abstract: By combining dihydroxyacetone as the active skin coloring agent in combination found with a blend of dispersion polymers and polyester polymers, an easily employed, self-tanning formulation is realized which produces a long lasting, naturally appearing coloring of the skin without any orange pigmentation being produced. In addition, tan colored skin produced by the present invention maintains the desired color for extended periods of time. In the present invention, the dispersion polymers stabilize the dihydroxyacetone as well as provide a thickening agent for the composition. In addition, the present invention also incorporates an oil soluble polyester polymer in combination with the other ingredients which achieves a formulation which provides a slow release of the active ingredient.

Abstract: Methods and apparatus for improving administration of drugs through the use of heat and other physical means. The present invention relates to the use of heat and other physical means in conjunction with specially designed dermal drug delivery systems, conventional commercial dermal drug delivery systems, or drugs delivered into a sub-skin depot site via injection and other methods to alter, mainly increase, the drug release rate from the dermal drug delivery systems or the depot sites to accommodate certain clinical needs.

Abstract: Photoaging skin care preparations and methods of treating wrinkled skin are described. The photoaging skin care preparations contain at least one triterpenoid derivative which is a substituted form of ursolinic, oleanolic, or betulic acid. The photoaging skin care preparations inhibit photoaging and prevent and ameliorate wrinkled skin. The methods of treating wrinkled skin involve applying an effective amount of the skin care preparation to the wrinkled skin.