Abstract: A method for performing a medical procedure, includes coupling a tip of a probe to tissue in an organ of a patient in order to apply the medical procedure using the probe. A force exerted by the tip on the tissue and a displacement of the tip created by the force are measured. A dependence of the force on the displacement is calculated. Based on the calculated dependence, a risk level of perforation of the tissue is estimated.

Abstract: A system and method is disclosed for measuring muscle reflexes (e.g., a bulbocavernosus reflex) as a tool for identifying/diagnosing dysfunctions (e.g., spinal cord abnormalities, bladder voiding dysfunction, and sexual organ dysfunction) non-invasively by using mechanical stimulation. The system and method includes a probe having a predetermined patient contacting portion, wherein when the contacting portion is moved into contact with a particular area of the patient (e.g., the patient's genitals), the contact induces a muscle reflex. The probe detects the pressure resulting from the contacting portion being abruptly and forcibly brought into contact with the particular area. Such detection is used to electronically initiate capture of electrical responses from a plurality of electrodes placed on the patient's skin in proximity to the particular area. Such electrical responses are processed to determine characteristics of the patient's reflexes of one or more muscles adjacent to the electrodes.

Abstract: Embodiment methods of treating a human or animal patient using a remotely controlled robotic catheter device inserting a handle of a catheter into a handle controller, inserting the catheter tubular portion into a resealable delivery channel forming a sterile barrier to a sled base, engaging a tip of the catheter with a sterile introducer disposed at an end of the sled base and engaged with the patient's body, positioning the catheter into the patient's body by remotely sending commands to the tele-robotic device to cause the sled member to advance toward the patient's body, and performing a diagnostic or therapeutic procedure on the patient using the catheter. Diagnostic or therapeutic procedures may include a mapping procedure, an ablation procedure, an angioplasty procedure, a drug delivery procedure; an electrophysiology procedure, a radiological procedure, and a medical device implantation or positioning procedure.

Abstract: A tissue sampling device includes for removing tissue from a target area in the body comprises a shaft having an outer surface. Two first portions and two second portions of the outer surface extend lengthwise of the shaft. Each first portion of the outer surface is associated with a different second portion and is spaced apart from its associated second portion. Each first portion of the outer surface at least partially defines a cutting edge extending in a straight line lengthwise of the shaft. Each first portion of the outer surface and its associated second portion are associated with a tissue-receiving surface extending lengthwise of the shaft. Each tissue-receiving surface defines a depression for receiving a tissue sample removed from the target area by the cutting edge of the associated first portion of the outer surface when the shaft is rotated about its longitudinal axis in the target area.

Abstract: The invention provides signal processing algorithms and apparatus for detecting bradykinesia, tremor, or other symptoms of neurological dysfunction in subjects, using three-dimensional sensors to tract finger and hand position. The invention provides Cartesian Genetic Programming networks and particular function blocks for such networks to enable identification of subjects exhibiting such symptoms.

Abstract: Provided herein are systems and methods that use a video content analysis algorithm to measure and quantify repetitive motion activity of a designated body part, including velocity, acceleration, frequency, and duty cycle, without applying sensors or other instrumentation to the body, for the purpose of preventing repetitive motion injuries. In some embodiments, the video-based direct exposure assessment system uses marker-less video and a video content analysis algorithm. The video content analysis algorithm is able to recognize and identify the pattern of repetitive motion, through a process known as cyclic motion analysis. Determination of the cycle pattern provides parameters for determining a body part's activity level, and thereby allows determination of the body part's activity level.

Abstract: The invention relates to a system for determining the quality of a bone structure, comprising: a body adapted for drilling through the bone structure; a first electrode arranged on the body so as to come into contact with the bone structure during drilling; a second electrode arranged on the body so as to come into contact with the bone structure at a distance from the first electrode during drilling; an electric generator adapted to apply an electric current between the first and second electrodes for a pre-determined period of time; a measuring device adapted (i) to measure the electric current, continuously and over the pre-determined period, an electrical magnitude representative of the aptitude of the bone structure for allowing electric current to pass therethrough and (ii) to deliver, continuously and over the pre-determined period, a signal representative of the quality of the bone structure between the contact surfaces of the first and second electrodes, using the determined electrical magnitude.

Abstract: Systems and methods for presenting force information related to a provisional is disclosed. A user interface may be provided for presenting objects on a display related to a knee joint, the user interface including a representation of an area of the knee joint for presentment on the display and a force center indicator for presentment on the display. The user interface providing an indication of when a position of the force center indicator corresponds to a desired position of the force center indicator.

Abstract: An unmet need of orthopedic practitioners is a clinically-relevant measurement device and technique to objectively quantify joint (e.g., knee) stability, including rotational stability. An apparatus and method is disclosed for performing a mechanical joint movement test, such as a knee pivot shift test, through the application of standardized dynamic loads (e.g., using a constant-tension spring or other mechanism). When used for knee evaluation, this test reliably induces the characteristic “pivot” tibial subluxation/reduction event in an ACL-deficient knee, allowing for more sensitive detection of deficiencies in rotational knee stability, quantification of the relative importance of knee stabilizers, and comparison of the performance of contemporary ACL reconstruction techniques. The test allows for better understanding joint biomechanics and for defining unique kinematic and kinetic signatures for common joint injuries, such as knee injuries, that will be valuable for diagnostic purposes.

Abstract: In a coil-type guidewire, a coating portion of the coil portion is formed by stacking a plurality of films. An innermost film of the coating portion is arranged to come between adjacent coils of the coil body, and voids are formed between the innermost film and a film disposed outside of the innermost film. By forming such voids, it is possible to easily bend the coating portion and to improve flexibility of the coating portion. As a result, the guidewire in which the coil body is covered with the coating portion and the coil body (the guidewire) can be easily curved.

Abstract: The present invention relates to a tissue collection system. The system includes an outer housing, a first cylindrical fenestrated member within and immovable relative to the outer housing, a second cylindrical fenestrated member defining an inner tissue collection chamber and being positioned within and rotatable relative to the first cylindrical fenestrated member, a plunger axially movable within the second fenestrated member, an elongate rod being connected to the plunger, and one or more stop units attached to the outer housing. The present invention also relates to methods for separating components of a tissue sample using a system according to the present invention.

Abstract: A biopsy device comprises a body, a needle, and a cutter actuation mechanism. The needle extends distally from the body. The cutter actuation mechanism rotates and translates the cutter relative to the body and relative to the needle. The cutter has an overmold presenting a lead screw and a hex portion. The cutter actuation mechanism comprises a first gear disposed about the hex portion of the overmold and a second gear engaged with the lead screw of the overmold by a nut that is integral with the second gear. The cutter actuation mechanism is operable to simultaneously rotate the first gear relative to the body at a first rotational speed and the second gear relative to the body at a second rotational speed. With the lead screw and the nut rotating at different rotational speeds, the lead screw rotates relative to the nut at a third rotational speed.

Abstract: A method of calculating an amount of exercise performed includes measuring noise based on a relative difference in displacement between a skin of a user and a sensor attached to the skin of the user, and determining a number of steps taken by the user based on the measured noise.

Abstract: Systems and methods for monitoring pulmonary edema or other thoracic fluid status in a subject use thoracic impedance histogram information. An internal or external processor circuit receives the thoracic impedance histogram information and uses it to compute and provide a lung fluid status indication. The thoracic impedance histogram information can include a count, mean or median of a histogram bin or subrange of bins within the histogram range.

Abstract: Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a membrane can be sealed over a digit extension to form a closed volume. The closed volume can be inflated via an inflation tube, and a reference pattern can be disposed within the closed volume along with a measurement assembly. In use, a user can put on the glove, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the rectal wall, optical fibers in the measurement assembly can move relative to a reference pattern, and a controller can sense light reflected through the fibers from the reference pattern. The controller can calculate or estimate various attributes of the prostate based on the reflected light, such as the palpable surface width or volume.

Abstract: Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a membrane can be sealed over a digit extension to form a closed volume. The closed volume can be inflated via an inflation tube, and a reference pattern can be disposed within the closed volume along with a measurement assembly. In use, a user can put on the glove, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the rectal wall, optical fibers in the measurement assembly can move relative to a reference pattern, and a controller can sense light reflected through the fibers from the reference pattern. The controller can calculate or estimate various attributes of the prostate based on the reflected light, such as the palpable surface width or volume.

Abstract: A system includes a first electrode at a tip of a tunneling tool and a second electrode. The system includes a circuit configured to determine whether the tip of the tunneling tool is within subcutaneous fat tissue or muscle tissue of a patient based on a measurement of an impedance between the first electrode and the second electrode.

Abstract: Employing outputted tones on a client device and/or headset is facilitated to identify hearing sensitivity of a user for both ears at various frequency bands and provide an indication of the users hearing sensitivity as compared to a normal hearing curve of a plurality of users on the same client device and/or headset or differing client devices and/or headsets.

Abstract: A system and method is disclosed for measuring muscle reflexes (e.g., a bulbocavernosus reflex) as a tool for identifying/diagnosing dysfunctions (e.g., spinal cord abnormalities, bladder voiding dysfunction, and sexual organ dysfunction) non-invasively by using mechanical stimulation. The system and method includes a probe having a predetermined patient contacting portion, wherein when the contacting portion is moved into contact with a particular area of the patient (e.g., the patient's genitals), the contact induces a muscle reflex. The probe detects the pressure resulting from the contacting portion being abruptly and forcibly brought into contact with the particular area. Such detection is used to electronically initiate capture of electrical responses from a plurality of electrodes placed on the patient's skin in proximity to the particular area. Such electrical responses are processed to determine characteristics of the patient's reflexes of one or more muscles adjacent to the electrodes.

Abstract: An expandable platform for measuring plantar pressures includes a multiplicity of modules (1) for measuring plantar pressures, each having mutually orthogonal sides and including its own array of sensors able to measure plantar pressure, and a control computer provided with a software for the treatment of the information coming from the sensors, able to display the static, postural and dynamic examination of the plantar pressures. The array of plantar sensors of each module (1) is connected with the control computer through an interface (2) positioned inferiorly to the measuring module (1) in such a way that each measuring module (1) is individually connectable for the transmission of data with the control computer, and is electronically and mechanically joined to other measuring modules (1) positioned adjacent to its own mutually orthogonal sides.