Abstract: The present disclosure is related to an apparatus and method for purification of biological feedstock, such as reducing or removing nitrogen containing compounds therein. The method can include subjecting the feedstock to a first separation step for obtaining a first fraction containing free fatty acids and nitrogen containing compounds, and collecting the residue containing acylglycerols. The first fraction is reacted with glycerol to obtain acylglycerols from the free fatty acid therein. This fraction is subjected to a second separation step for obtaining a second fraction containing nitrogen containing compounds, which is discharged as waste-product. The remains from the second separation contain formed acylglycerols and are collected.

Abstract: The invention relates to a solid composition comprising at least 90.0 wt. % bis(2-hydroxyethyl) terephthalate (BHET), as based on dry weight and having a pore volume in the range of 0.20 to 1.0 cm3/g. The porosity is above 25% or even above 35%. The solid composition is made by crystallisation, followed by granulation and fluid bed drying.

Abstract: The present invention relates to a rheology additive, according to which A) said additive consists of: a) at least one symmetrical fatty diamide of formula (I): (AGH)-CONH-(PMDA)-NHCO-(AGH) (I) with: (AGH): hydroxylated fatty acid residue R1CO2H, without —CO2H group, with R1 of C18 to C20 comprising a hydroxyl group, —NHCO— or —CONH—: amide group, —(PMDA): residue without amine groups of 1,5-pentamethylenediamine; or alternatively according to which: B) said additive comprises: a) at least one symmetrical fatty diamide as defined above according to formula (I) and, in addition, b) at least one other symmetrical fatty diamide of formula (II): (AGH)-CONH-(R)-NHCO-(AGH) (II) with (AGH), —NHCO— and —CONH— having the same definition as that above in said formula (I), and (R) being the residue without amine groups of a diamine, other than (PMDA), chosen from a cycloaliphatic, aliphatic or aromatic diamine.

Abstract: The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

Abstract: An unground N?-long chain acyl lysine crystal production method that includes: preparing a solution having at least one type of N?-long chain acyl lysine dissolved in an acidic or basic solvent including water and/or one type selected from water-soluble organic solvents; dipping the solution into an acidic solution having a pH of at least 0.2 and less than 2.0, at a temperature of no more than 20° C.; and crystallizing N?-long chain acyl lysine crystals.

Abstract: The present disclosure relates to a method for continuously producing a dicarboxylate-based composition and a production system therefor, the method improving a production yield by optimizing process variables of each reactor of a reaction unit in which a plurality of reactors are connected in series.

Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.

Abstract: Methods of depolymerizing lignin and products obtained therefrom. The methods include reacting lignin in a liquid solvent comprising an oxidation catalyst with the solvent being in contact with O2 gas. The solvent can include aprotic polar solvents. The oxidation catalyst can include heterogeneous catalysts. The methods can be used in the oxidative catalytic fractionation of raw biomass to generate soluble aromatic monomers and a solid carbohydrate residue. Depolymerized lignin products include phenolic and benzoquinone monomers, such as p-hydroxybenzoic acid, vanillin, syringaldehyde, vanillic acid, and/or syringic acid.

Abstract: The disclosure discloses a nicotinamide dummy template surface molecularly imprinted polymer, a preparation method and application thereof, and belongs to the technical field of chemical materials. The preparation method of the disclosure includes the steps of preparing a modified silica gel carrier, preparing a dummy template surface molecularly imprinted polymer and the like. The disclosure uses nicotinamide, a structural analogue of imidacloprid and acetamiprid, as a dummy template to prepare a silica gel surface molecularly imprinted polymer. The polymer not only can effectively avoid pollution caused by the leakage of template molecules, but also can specifically remove imidacloprid and acetamiprid from water-soluble tea extracts. The removal rate of imidacloprid and acetamiprid is greater than 96% and 93%, respectively, and the loss of tea polyphenols in the extracts is less than 10%.

Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.

Abstract: The invention relates to a process for the manufacture of diesel range hydrocarbons wherein a feed is hydrotreated in a hydrotreating step and isomerised in an isomerisation step, and a feed comprising fresh feed containing more than 5 wt % of free fatty acids and at least one diluting agent is hydrotreated at a reaction temperature of 200-400° C., in a hydrotreating reactor in the presence of catalyst, and the ratio of the diluting agent/fresh feed is 5-30:1.

Abstract: The invention relates to a single cycle process for preparing D,L-methionine from an alkali methioninate solution obtained by alkaline hydrolysis of 5-(2-methylmercaptoethyl)hydantoin, in which the D,L-methionine is obtained by neutralizing the alkali methioninate solution with carbon dioxide at elevated temperature and subsequently crystallizing D,L-methionine in the presence of seed crystals.

Abstract: Methods of refining palm oil in order to produce a refined, bleached and deodorized palm oil with reduced level of 3-monochloropropane-1, 2-diol (3-MCPD) ester are disclosed. The methods may include premixing a palm oil with an acid to chelate metals and form a reaction mixture, and subjecting the reaction mixture to hydrodynamic cavitation mixing for less than 1 second.

Abstract: A method for producing a catalyst for unsaturated carboxylic acid synthesis is proposed. The method includes: obtaining a dried product by drying and heat-treating a starting material mixed liquid in which supply source compounds of respective catalyst component elements are integrated; and forming a catalyst precursor by supporting powder to be supported on a carrier in the form of a particle aggregate. The powder to be supported is either the dried product or obtained from the dried product. The method further includes calcining the catalyst precursor to form the catalyst. The mass loss rate of the powder to be supported at 300° C. is less than 5 percent by mass, and the difference between the mass loss rate of the powder at 370° C. and the mass loss rate of the powder at 300° C. is not less than 1 percent by mass and not more than 6 percent by mass.

Abstract: The present invention relates to a process for the preparation of tapentadol and analogs or compounds or stereoisomers of formula (I), Formula I wherein, A is aryl, heteroaryl, and cycloalkyl; R is H, OH, OR1, halogen, C1-C12 alkyl, cycloalkyl, aryl or heteroaryl; R1 is C1-C12 alkyl, cycloalkyl, aryl or heteroaryl, wherein each of these groups may further be substituted with one or more substituent selected from H, OH, halogen, CN, NO2, C1-C4 alkyl or phenyl. Further, the multi-step process involves no column chromatography purification until the very last step. This makes this process highly commercially viable and industrially useful.

Abstract: The present invention relates to a method for isomerizing a 3-(Z)-unsaturated carboxylic acid of the formula 1-Z or a salt thereof, wherein R2 is C1-C24-alkyl, C2-C24-alkenyl having 1, 2, 3 or more than 3 C—C double bonds, unsubstituted or substituted C5-C12-cycloalkyl, or unsubstituted or substituted aryl; R1 is hydrogen or has one of the definitions specified for R2; with the proviso that R2 has a higher priority than R1 in accordance with IUPAC; to give a 3-(E)-unsaturated carboxylic acid of the formula I-E or a salt thereof, wherein the isomerization of the compound of the formula 1-Z is effected in the presence of an anhydride of an organic acid and a base or in the presence of a ketene of formula CR11R12C(0), wherein R11 and R12 are as defined in the claims and in the specification and a base.

Abstract: Provided herein are compositions, methods and uses that relate to or result from providing separation media having at least one flocculant ligand covalently attached to a base surface or support, and the separation and/or purification of biological molecules using the separation media of the present disclosure. Certain embodiments provide separation media which under certain modes of operation, enhance the separation of the molecule of interest from impurities.

Abstract: A method of producing a low-fat product from a starting material made of a fat and/or oil containing plant- or animal item includes providing the starting material at a temperature of at least 35° C. and extracting a greater part of the extractable oil and/or fat originally contained in the plant or animal item from the starting material using a first decanter centrifuge. The first decanter centrifuge leaves a residue of solids and liquids. The residue forms the low-fat product.

Abstract: The present invention refers to a method for the production of haloalkane sulfonic acid, in which SO3 and an haloalkane are contacted with each other in the presence of a solvent, said solvent does constitute a superacid and the combination of said solvent with one or more of the reactants also gives rise to a superacid.

Abstract: Disclosed is a method for removing acetaldehyde and other permanganate reducing compounds (PRCs) from a process stream in the methanol carbonylation process for making acetic acid. The method includes the steps of forming an azeotrope to reduce the boiling point of the acetaldehyde and other PRCs to facilitate separation of the acetaldehyde and other PRCs from the process. In one embodiment the azeotrope comprises butane and acetaldehyde.