Patents Examined by Yunus Abdul
  • HIV-1 envelope glycoprotein
    Patent number: 8586056
    Abstract: The present application relates to a novel HIV-1 envelope glycoprotein which may be utilized as an HIV-1 vaccine immunogen, antigens for crystallization and for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: November 19, 2013
    Assignee: International AIDS Vaccine Initiative
    Inventors: Sanjay K. Phogat, Wayne C. Koff, Charles Richter King, Denise Wagner, Simon Hoffenberg
  • Respiratory synctial virus (RSV) sequences for protein expression and vaccines
    Patent number: 8580270
    Abstract: The invention provides RSV fusion (F) protein ectodomain polypeptide sequences and nucleotide sequences encoding them, as well as cells containing the invention's polypeptide and nucleotide sequences. The invention further provides VLPs that contain the invention's polypeptides, and methods for using the VLPs for protein expression and vaccine formulation. Also provided are methods for distinguishing between subjects immunized with the invention's compositions and subjects infected with RSV.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: November 12, 2013
    Assignee: University of Massachusetts
    Inventor: Trudy G. Morrison