Patents Examined by Zohreh A. Fay
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Patent number: 12290529Abstract: Disclosed herein are methods of administering compositions comprising a mixture of salts that induce purgation of the colon and are useful to cleanse the colon. Furthermore, the disclosed methods prevent degradation of PEG and allow for cleansing of the colon without the use of adjunct laxatives, including stimulant laxatives such as bisacodyl. The disclosed methods are superior to the prior art in that they allow for higher tolerability, improved safety, lower volumes, and improved patient compliance.Type: GrantFiled: August 2, 2024Date of Patent: May 6, 2025Assignee: Braintree Laboratories, Inc.Inventors: Edmund V. Dennett, Mark Cleveland, Russell W. Pelham, Matthew Walker
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Patent number: 12285447Abstract: The present disclosure provides methods and pharmaceutical compositions for treating ulcerative colitis (UC) in a subject in need thereof. In particular, the compositions described here comprise or are designed based on fecal bacteria associated with FMT-based UC treatment success or failure. Also provided are methods for screening patients for their suitability for a fecal bacteria-based UC treatment. Further provided are methods for screening fecal donors for optimized source materials for producing a fecal bacteria-based pharmaceutical composition.Type: GrantFiled: October 19, 2021Date of Patent: April 29, 2025Assignee: FINCH THERAPEUTICS HOLDINGS LLCInventor: Thomas Julius Borody
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Patent number: 12286385Abstract: A soil microbial regulator for enhancing plant stress resistance, which includes the following components in parts by weight: 30-50 parts of coconut coir, 30-50 parts of Eucheuma, 10-30 parts of mushroom residue, 20-30 parts of Guayule and 0.4-1.6 parts of a composite bacterial agent. The present invention uses discarded mushroom residue and coconut coir as raw materials, and Guayule and Eucheuma are added; under the action of a composite bacterial agent, the raw materials are fermented; the soil microbial regulator prepared by fermentation can adjust the soil structure, improve soil microbial structure, provide sustainable nutrition for crop growth, significantly promote crop growth, improve crop resistance to diseases and insect injury, effectively reduce crop incidence rate, enhance crop resistance, realize the purpose of increasing yield and income, and achieve high and stable crop yield.Type: GrantFiled: June 29, 2021Date of Patent: April 29, 2025Assignee: HAINAN UNIVERSITYInventors: Chunxiu Qin, Wenbo Liu, Pengfei Jin, Chunhua Lin
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Patent number: 12279618Abstract: Disclosed is the use of dihydroporphin derived from chlorophyll as a plant growth regulator. Compared with the prior art, a class of new type plant growth regulators are provided; since the direct decomposition product of chlorophyll is used as a product, the preparation and processing thereof are easier, the structure is relatively simple, and tedious reactions and preparations such as further chemical coordination/chelation/purification are eliminated, so that the product is more environmentally friendly and safer; the product has a better solubility than the corresponding metal chelate and has a more convenient method of use, making it more convenient to be used in the fields; the stability of the product has been improved, with stable quality assurance and a longer shelf life; the product has a natural source and uses a low amount of same due to a low effective dosage, thereby improving the utilization rate of silkworm excrement resources.Type: GrantFiled: June 27, 2019Date of Patent: April 22, 2025Assignee: ANQING BETTER BIOENGINEERING CO., LTDInventors: Junhai Huang, Liming Chen, Letian Wang, Dongfeng Meng, Ming Li, Jin Hu, Yong Ren
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Patent number: 12252672Abstract: The present disclosure relates to rheology modified, low foaming aqueous antimicrobial compositions. The compositions are phase stable under acidic conditions, and do not need to be rinsed from the surface to which they are applied. The present disclosure further relates to methods of use thereof.Type: GrantFiled: January 31, 2022Date of Patent: March 18, 2025Assignee: ECOLAB USA INC.Inventors: Junzhong Li, Steven J. Lange, Richard Staub, David D. McSherry
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Patent number: 12245590Abstract: The present invention relates to a method for controlling weeds including a step of performing a spot treatment of at least one PPO inhibitor in a cultivation area of soybean, corn, or cotton. According to the present invention, it is possible to provide a method for exerting an excellent control effect in weed control.Type: GrantFiled: March 19, 2020Date of Patent: March 11, 2025Assignee: SUMITOMO CHEMICAL COMPANY, LIMITEDInventor: Yoshinao Sada
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Patent number: 12239133Abstract: At present, many herbicidal compositions have been developed and used, but there are many types of weeds to be controlled, and their development lasts for a long period of time. Accordingly, it has been desired to develop a herbicidal composition having a wider herbicidal spectrum, high activity and residual activity and thereby capable of controlling undesired plants for a long period of time. The present invention provides a herbicidal composition comprising as active ingredients (a) tolpyralate and (b) pyroxsulam.Type: GrantFiled: May 18, 2020Date of Patent: March 4, 2025Assignee: ISHIHARA SANGYO KAISHA, LTD.Inventors: Taketo Suganuma, Shota Fukuda
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Patent number: 12239737Abstract: Oral preparations of microcapsules and nanoparticles including an inhibitor of the mammalian target of rapamycin. The preparations are intended to assist with the treatment and prevention of cancer, neurocognitive dysfunction, genetically predisposed disorders, and age-related disorders. The embodiments discussed address the present need for alternative preparations or manufacturing processes that ensure efficacy while improving other performance characteristics such as storage stability, biodistribution, dosage cost, etc.Type: GrantFiled: August 2, 2021Date of Patent: March 4, 2025Assignee: Rapamycin Holdings, Inc.Inventors: Dana Vaughn, Neal K. Vail
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Patent number: 12239659Abstract: Disclosed herein are methods of administering compositions comprising a mixture of salts that induce purgation of the colon and are useful to cleanse the colon. Furthermore, the disclosed methods prevent degradation of PEG and allow for cleansing of the colon without the use of adjunct laxatives, including stimulant laxatives such as bisacodyl. The disclosed methods are superior to the prior art in that they allow for higher tolerability, improved safety, lower volumes, and improved patient compliance.Type: GrantFiled: June 14, 2024Date of Patent: March 4, 2025Inventors: Edmund V. Dennett, Mark Cleveland, Russell W. Pelham, Matthew Walker
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Patent number: 12239130Abstract: Methods of reducing injury to crop foliage and achieving weed control using encapsulated acetamide herbicides are described. Herbicidal microcapsules comprising herbicide core material and a shell wall encapsulating the core material are also described. The microcapsules provide reduced crop injury through controlled herbicide release.Type: GrantFiled: October 12, 2020Date of Patent: March 4, 2025Assignee: MONSANTO TECHNOLOGY LLCInventors: William Abraham, David Z. Becher, Brett H. Bussler, Amanda C. Herr, S. Douglas Prosch
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Patent number: 12232491Abstract: This invention relates to a coating for seeds comprising a polymeric material, a method of making and using the coating for improving the adherence of seeds to sloped surfaces, and seeds containing said coating. The invention also relates to a horticulture system for distributing the coated seeds to landscaping and/or agricultural surfaces.Type: GrantFiled: January 21, 2022Date of Patent: February 25, 2025Assignee: Milliken & CompanyInventors: Thomas A. Canada, Dominick J. Valenti, Walter P. Horton, Robert L. Schuette
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Patent number: 12226534Abstract: Article side polymers useful in the packaging of transdermal patches are disclosed. These films do not absorb skin permeation enhancers that are contained in transdermal patches including keto acids such as levulinic acid or sulfoxides such as an alkyl sulfoxide, e.g., dimethyl sulfoxide. Using such polymeric film, multilayer pouch constructions can be manufactured which include other polymeric layers, such as aluminum foil for moisture and oxygen barrier properties, polyester for tear resistance and paper layers for optimal printing and design.Type: GrantFiled: July 5, 2017Date of Patent: February 18, 2025Assignee: Agile Therapeutics, Inc.Inventors: Agis Kydonieus, C. Gregory Arnold, Robert G. Conway, Thomas M. Rossi
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Patent number: 12226384Abstract: Disclosed are a peramivir solution inhalant and a preparation method thereof, the solution inhalant includes: peramivir, an osmotic pressure regulator, a pH regulator, and water, wherein concentration of peramivir is greater than 15 mg/ml; concentration of the osmotic pressure regulator is less than 8 mg/ml; pH value of the solution inhalant ranges from 5.0 to 6.0; the peramivir solution is sterilized in a non-heating manner; the osmotic pressure regulator is selected from sodium chloride or glucose. The solution inhalant has a better stability and a good pulmonary targeting effect, which significantly improves pharmaceutical efficacy and safety.Type: GrantFiled: August 24, 2021Date of Patent: February 18, 2025Assignee: Guangzhou Nanxin Pharmaceutical Co., Ltd.Inventors: Shixi Zhang, Yuhuan Feng, Dong Miao
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Patent number: 12207655Abstract: Provided herein are compounds of general Formula I: or agriculturally acceptable salts thereof. The compounds of Formula I can be used to improve the health of plants. For example, the compounds of Formula I can be used to inhibit a microbial pathogen of a plant, or to increase resistance of a plant to one or more abiotic stress.Type: GrantFiled: February 14, 2020Date of Patent: January 28, 2025Assignee: NUTRIEN AG SOLUTIONS (CANADA) INC.Inventors: Michael Fefer, Jun Liu, Yuichi Terazono, Kenneth Ng, Youqing Shen
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Patent number: 12201114Abstract: The invention relates to aqueous benzisothiazoline-3-one dispersions of sodium-1,2-benzisothiazoline-3-one particles dispersed in water. The dispersions contain: (a) between 15 wt.-% and 35 wt.-% of sodium-1,2-benzisothiazoline-3-one; and (b) ad. 100 wt.-% of water having a content of sodium ion in the range from 4 wt.-% to 10 wt.-% with respect to water contained in the dispersion. The invention further relates to the use of the claimed dispersions for preserving water-based products of all types, in particular, cleaning and household products, plastics dispersions, paints, plasters, adhesives, sealing compounds, paper coating materials, textile softeners and sizing agents, washing raw materials, surfactants, polishing agents, spinning baths, cooling lubricants, leather treatment agents and silicone and bitumen emulsions.Type: GrantFiled: February 14, 2020Date of Patent: January 21, 2025Assignee: Thor GmbHInventor: RĂ¼diger Baum
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Patent number: 12188939Abstract: Methods of obtaining and kits that can be used to obtain an optical super-resolution image of a sample or a portion thereof or an individual or a portion thereof. In various examples, the individual is an individual with cancer. In various examples, a method includes contacting a sample or individual with one or more aluminosilicate nanoparticle(s) that have at least one organic fluorophore molecule covalently bonded to the aluminosilicate network of the nanoparticle(s), or a composition including the aluminosilicate nanoparticle(s); irradiating the sample or the individual, thereby exciting at least one of the fluorophore molecules of an individual aluminosilicate nanoparticle; and obtaining a fluorescence image or a sequence of fluorescence images, which can be processed to obtain a super-resolution image of the sample or the individual. In various examples, the sample is a biological sample, living or fixed tissues and/or cells, or a biopsy obtained from an individual.Type: GrantFiled: October 14, 2021Date of Patent: January 7, 2025Assignee: Cornell UniversityInventors: Jacob Erstling, Joshua A. Hinckley, Nirmalya Bag, Ulrich B. Wiesner
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Patent number: 12186330Abstract: This invention relates to methods and compositions for use improving cell viability, particularly neural cell viability, and more particularly to methods and compositions for use improving cell viability by reducing reactive oxygen metabolite-mediated oxidative damage in a cell, regulating redox homeostasis in a cell, or reducing mitochondrial dysfunction in a cell. The invention further relates to the administration of the bile acid tauroursodeoxycholic acid (TUDCA) in combination with phenylbutyric Acid (PBA) to improve cell viability, and treat at least one symptom associated with, prevent the time of onset of, or slow the development of a disease related to oxidative stress.Type: GrantFiled: November 2, 2021Date of Patent: January 7, 2025Assignee: Amylyx Pharmaceuticals Inc.Inventors: Joshua Cohen, Justin Klee
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Patent number: 12178812Abstract: The present invention relates to a dosage form comprising an aqueous solution of a vinca alkaloid drug or its pharmaceutically acceptable salt in a flexible infusion container, and a light protective secondary packaging containing the flexible infusion container, wherein the dosage form is ready-to-infuse and wherein the aqueous solution is stable at room temperature.Type: GrantFiled: June 17, 2021Date of Patent: December 31, 2024Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITEDInventors: Subhas Balaram Bhowmick, Prashant Kane, Samarth Kumar, Ramaji Karshanbhai Varu, Nisarg Bipinchandra Mistry, Swapnil Ramesh Patil
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Patent number: 12171853Abstract: Several embodiments disclosed herein relate to formulations having antimicrobial and/or sanitizing effects, and uses of the same. In particular, the formulations and methods of using same provide, in several embodiments, an immediate and a persistent antimicrobial effect against a broad spectrum of microorganisms.Type: GrantFiled: September 2, 2021Date of Patent: December 24, 2024Assignee: Innovative BioDefense, Inc.Inventors: Jesse Cozean, Colette Cozean, Susan Goldsberry
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Patent number: 12171230Abstract: The present invention provides compositions comprising herbicidally active compounds (A) and (B), where (A) represents one or more compounds of the general formula (I) or their agrochemically acceptable salts [component (A)], and (B) represents one or more herbicides [component (B)]. The application furthermore relates to a method and to the use of the herbicidal composition according to the invention for controlling harmful plants or for regulating growth.Type: GrantFiled: December 2, 2019Date of Patent: December 24, 2024Assignee: BAYER AKTIENGESELLSCHAFTInventors: Klaus Trabold, Lothar Lorentz, Hubert Menne, Elmar Gatzweiler, Christopher Hugh Rosinger, Klaus Bernhard Haaf