Patents Examined by Zohreh A. Fay
  • Patent number: 12108758
    Abstract: A low viscosity agricultural adjuvant for spraying syrup comprising emulsifying agents, surfactants, suspending agents, defoamer, clays and water. This invention is directed to the agricultural sector and it is an adjuvant that can be classified as an activator and modifier of spraying and other modifiers. The adjuvant when added to the agricultural spray syrup, assists in the compatibility of phytosanitary products used for the formation thereof. This invention avoids the formation of possible organic and inorganic scale, which can affect the spraying equipment. The invention confers high syrup conditioning capacity and provides a homogeneous and fluid syrup preparation, with high efficiency from the outlet of the spray nozzle to the deposition of droplets in the crops.
    Type: Grant
    Filed: September 23, 2022
    Date of Patent: October 8, 2024
    Assignee: FORQUIMICA AGROCIENCIA LTDA
    Inventors: Edson Geraldo Rosini, Paulo Assis Dos Passos
  • Patent number: 12109214
    Abstract: The invention relates to pharmaceutical compositions comprising 6-thioguanine (6-TG) wherein the composition is formulated for release of 6-TG in the distal intestine. Methods for treating a disease or condition of the distal ileum that responds to 6-TG wherein the 6-TG is released in the distal intestine are also disclosed.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: October 8, 2024
    Assignee: PRODRUGXTEND PTY LTD
    Inventors: Timothy Florin, Amirali Popat, Siddharth Jambhrunkar
  • Patent number: 12102713
    Abstract: Provided are an ocular surface drug-retaining agent that enables an excellent improvement in retainability of a medicament on an ocular surface and an eye drop containing the agent. An ocular surface drug-retaining agent containing a copolymer having three different kinds of constituent units at a specific ratio can express an excellent effect of retaining a medicament on an ocular surface (in particular, a corneal surface) to allow the effect or action of the drug to be sustained over a long period of time.
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: October 1, 2024
    Assignees: NOF CORPORATION, Kinki University
    Inventors: Noriaki Nagai, Shunsuke Sakurai, Eiji Harata
  • Patent number: 12090144
    Abstract: The present disclosure provides a photocurable hydrogel loaded with VH298-modified exosome and a method of preparation and use thereof, belonging to the technical field of medical materials. In the present disclosure, an engineered exosome (VH-EVs) is prepared by combining an exosome with VH298, a hypoxia-inducible factor 1 alpha (HIF-1?) stabilizer; and a solid auxiliary material is loaded by a GelMA hydrogel. The material is not only conducive to sustained release of the engineered exosome, but improves angiogenesis and accelerate wound healing, showing a relatively high value for use.
    Type: Grant
    Filed: July 29, 2022
    Date of Patent: September 17, 2024
    Assignee: Chinese PLA General Hospital
    Inventors: Cuiping Zhang, Yaxi Wang, Kui Ma, Xiaobing Fu
  • Patent number: 12010999
    Abstract: The present invention discloses an application of an endophytic fungi FO-R20 in prevention and treatment of rice neck or panicle blast, and belongs to the technical filed of microbial applications. The Falciphora oryzae FO-R20 with a deposit number of CCTCC M 2021505 is prepared into a seed coating agent or solid fungal fertilizer and applied to rice seeds; and in the culture process, the strain is colonized at the roots of rice, thus the disease resistance of rice to neck or panicle blast is remarkably enhanced, the prevention and treatment efficiency reaches 86.91%-90.85%, and the disease index is reduced by 64.92-72.07. The biological prevention and treatment effect of the endophytic fungi Falciphora oryzae FO-R20 against rice neck or panicle blast has great value by promotion and applications thereof in the field of agriculture.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: June 18, 2024
    Assignee: ZHEJIANG ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Fucheng Lin, Zhenzhu Su, Lin Li, Yan Liang, Kunlun Shen
  • Patent number: 12005053
    Abstract: Veterinary pharmaceutical compositions for direct systemic introduction, also known as DSI pharmaceutical compositions. One veterinary pharmaceutical composition for direct systemic introduction includes about 10-17 dry mass % bovine gelatin; about 10-17 dry mass % mannitol; about 0-1 dry mass % of a surfactant; and about 65-80 dry mass % of the active pharmaceutical ingredient which is a proton pump inhibitor. A method of manufacturing a veterinary pharmaceutical composition for direct systemic introduction includes combining one or more pharmacologically inactive compounds to form a first solution; using one or more surfactants to form a second solution; adding an active pharmaceutical ingredient to the second solution to form a first mixture; adding the first solution to the first mixture to form a pre-formulation; freezing the pre-formulation; and lyophilizing the pre-formulation.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: June 11, 2024
    Assignee: NewMarket Pharmaceuticals LLC
    Inventors: Mark Ridall, David Rock
  • Patent number: 11992007
    Abstract: An aqueous formulation that reduces the damage caused by spring frosts in plants having: (a) 0.001-2% by weight PVA micro/nanoparticles having a molecular weight of 10,000-100,000 g/mol and 1-20% acetate groups; (b) 0.0001-0.4% by weight stabilising agents; (c) 0.0005-0.05% by weight category IV adjuvants; (d) 0.00025-4% by weight emulsifier; (e) 0.003-6% by weight sodium hydroxide; and (f) 0.0065-13% by weight hydrochloric acid at 37% weight/weight and 1.18 g/mL density; a process for producing the aqueous formulation, and to uses.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: May 28, 2024
    Assignees: UNIVERSIDAD DE CONCEPCION, CENTRO DE INVESTIGACION DE POLIMEROS AVANZADOS
    Inventors: Saddys María Rodriguez Llamazares, Constanza Sabando Correa, Walther Ide, Richard Mauricio Bastias Ibarra
  • Patent number: 11992010
    Abstract: The present disclosure provides the use of 4-(Phenylethynyl) benzoic acid in preparing a plant growth regulator. 4-(Phenylethynyl) benzoic acid has a formula as C15H10O2, a molecular weight of 222.2390. The optimum concentration of 4-(Phenylethynyl) benzoic acid in the plant growth regulator is in a range of 10 ?M to 200 ?M. The plant growth regulator further contains a pesticidally acceptable carrier. The present disclosure further provides the use of 4-(Phenylethynyl) benzoic acid in regulating plant growth. In the use of 4-(Phenylethynyl) benzoic acid in preparing a plant growth regulator of the present disclosure, 4-(Phenylethynyl) benzoic acid has the ABA-like effects, and is more stable, easily available, cheaper, and environmentally friendly. Therefore, the present disclosure is suitable for large-scale popularization.
    Type: Grant
    Filed: September 23, 2022
    Date of Patent: May 28, 2024
    Assignee: China Jiliang University
    Inventors: Pei Xu, Pingping Fang, Xiaofang Li, Zhuoyi Wang, Ting Sun, Xinyang Wu, Peipei Zhang
  • Patent number: 11985914
    Abstract: Methods and systems are presented for making good use of recently obtained biometric data, for configuring propagule capsules (e.g. containing seeds or spores with growth media and other helpful materials) for deployment via drones so that each has an improved chance of survival, and for configuring drones or piloted craft for safe fleet deployment in remote locations.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: May 21, 2024
    Assignee: DRONESEED CO.
    Inventors: Matthew Mehdi Aghai, Grant Everest Canary, John William Thomson, Tiffani Manteuffel-Ross
  • Patent number: 11968983
    Abstract: The present disclosure discloses a tobacco leaf foliar spraying substance for reducing harmful ingredients in cheroot, a method for reducing carcinogenic components in flue-cured tobacco leaves and flue-cured tobacco shreds. The tobacco leaf foliar spraying substance contains a lotus leaf extract, the harmful chemical ingredients comprise N-nitrosonornicotine, 4-(N-methyl-nitrosamine)-1-(3-pyridinyl)-1-butanone, N-nitrosoanabasine and N-nitrosoanatabine. Foliar spraying is performed on a fertile field by using the lotus leaf extract before tobacco leaves are harvested and modulated, which not only significantly promotesagronomic characters and economic traits of tobacco and alleviates tobacco leaf browning but also effectively reduces harmful chemical ingredients unique to tobacco leaves, such as nitrosamine and nicotine.
    Type: Grant
    Filed: June 17, 2023
    Date of Patent: April 30, 2024
    Assignee: HUBEI INSTITUTE OF TOBACCO SCIENCE
    Inventors: Chunlei Yang, Jinpeng Yang, Jun Zhou, Mei Yang, Yong Yang, Jun Yu, Zongping Li, Xiongfei Rao, Guangjiong Qin, Baoming Qiao, Ruoshi Bai, Yanjun Ma, Xianbao Deng, Wenzhang Qin, Kaixiao Fan, Candong Deng, Yongle Wei, Youlun Fan
  • Patent number: 11957126
    Abstract: A granulated defoamer has a dry ammonium sulfate which has been combined with a mixture of at least two of the following materials, anionic surfactant, an organic acid and a defoamer. The method of creating the granulated defoamer and method of using the same in agricultural spraying of vegetation.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: April 16, 2024
    Assignee: KOP-COAT, INC.
    Inventors: Ronald W. Clawson, Jr., Bruce W. Dawson, Saddam Hussain
  • Patent number: 11944099
    Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).
    Type: Grant
    Filed: February 11, 2021
    Date of Patent: April 2, 2024
    Assignee: CORTEVA AGRISCIENCE LLC
    Inventors: Ronald J. Heemstra, Ronald Ross, Jr., Timothy P. Martin, Nicolaas Vermeulen, John F. Daeuble, Sr., Joseph D. Eckelbarger, Alex Nolan, Kaitlyn Gray, David A. Demeter, Ricky Hunter, Tony K. Trullinger
  • Patent number: 11324686
    Abstract: The invention provides a topical o/w emulsion which moisturizes, and protects, repairs or restores the skin lipid barrier of a mammal. The topical o/w emulsion composition comprises: (a) a discontinuous oil phase; (b) a continuous aqueous phase comprising water; (c) a thickening agent; (d) at least one lamellar membrane structure comprising (i) a phospholipid, (ii) a fatty alcohol, and (iii) a fatty acid; and wherein in use the composition has a water vapor transmission rate of less than about 70 g.m?2.hr?1 measured in vitro using the modWVTR test methodology.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: May 10, 2022
    Assignee: LG HOUSEHOLD & HEALTH CARE LTD.
    Inventors: Pallav Arvind Bulsara, Martyn J. Clarke, Anthony V. Rawlings
  • Patent number: 11273107
    Abstract: New natural-based, eye make-up cosmetic composition, comprising graphene, being free from synthetic polymers, provided with optimal features for ease of distribution and high-definition.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: March 15, 2022
    Assignee: PRODOTT GIANNI S.R.L
    Inventors: Cecilia Anselmi, Marisanna Centini, Giulia Signori, Maria Francesca Tola
  • Patent number: 11268049
    Abstract: The present disclosure relates to rheology modified, low foaming aqueous antimicrobial compositions. The compositions are phase stable under acidic conditions, and do not need to be rinsed from the surface to which they are applied. The present disclosure further relates to methods of use thereof.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: March 8, 2022
    Assignee: Ecolab USA Inc.
    Inventors: Junzhong Li, Steven J. Lange, Richard K. Staub, David D. McSherry
  • Patent number: 11253441
    Abstract: The invention provides for a topical o/w emulsion having moisturizing, and protecting, repairing or restoring the skin lipid barrier of the lips of a mammal, and is a topical oil-in-water emulsion composition comprising: (a) a discontinuous oil phase; (b) a continuous aqueous phase comprising water; (c) a thickening agent; (d) at least one lamellar membrane structure comprising (i) an alkyl amphiphilic component, (ii) an ester of a branched fatty acid and a branched fatty alcohol, (iii) a fatty acid, (iv) a fatty alcohol, and optionally (v) a phospholipid; and wherein in use the composition has a water vapor transmission rate of less than 65 g·m?2·hr?1 measured in vitro.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: February 22, 2022
    Assignee: LG HOUSEHOLD & HEALTH CARE LTD.
    Inventors: Pallav Arvind Bulsara, Martyn J. Clarke, Anthony V. Rawlings
  • Patent number: 11253474
    Abstract: Disclosed herein is a liquid pharmaceutical formulation substantially free of water, comprising: (i) amlodipine or a pharmaceutically acceptable salt thereof, (ii) at least one pharmaceutically acceptable excipient, and (iii) a sufficient amount of a vehicle comprising glycerin. Also disclosed herein is a liquid pharmaceutical formulation substantially free of water and ethanol, comprising: (i) amlodipine or a pharmaceutically acceptable salt thereof, (ii) at least one pharmaceutically acceptable excipient, and (iii) a sufficient amount of a vehicle comprising glycerin.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: February 22, 2022
    Assignee: LIQMEDS WORLDWIDE LIMITED
    Inventors: Jayanta Kumar Mandal, Malay Patel, Swati Nagar, Michael Paul DeHart
  • Patent number: 11241515
    Abstract: Described is a method for the production of substantially spherical calcium phosphate particles that involves subjecting a composition comprising calcium phosphate to dual asymmetric centrifugation (DAC). Also described are products of the method.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: February 8, 2022
    Assignee: OSTEONOVUS LLC
    Inventors: Brian Schlossberg, Olivia Norman
  • Patent number: 11229597
    Abstract: The present invention relates to a novel pharmaceutical composition comprising doxycycline for topical application, in particular to the eye and eyelids. The invention also relates to this topical composition for use in the treatment of bacterial infections of the skin and mucous membranes.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: January 25, 2022
    Assignees: HORUS PHARMA, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marion Dubald, Sandrine Bourgeois, Hatem Fessi, Martine Claret
  • Patent number: 11229618
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: January 25, 2022
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku