Patents Examined by Zohreh A. Fay
  • Rheology modified low foaming liquid antimicrobial compositions and methods of use thereof
    Patent number: 10563153
    Abstract: The present disclosure relates to rheology modified, low foaming aqueous antimicrobial compositions. The compositions are phase stable under acidic conditions, and do not need to be rinsed from the surface to which they are applied. The present disclosure further relates to methods of use thereof.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: February 18, 2020
    Assignee: Ecolab USA Inc.
    Inventors: Junzhong Li, Steven J. Lange, Richard K. Staub, David D. McSherry
  • Agent for stabilizing keratin fibers with 5-ring heterocycles
    Patent number: 10561594
    Abstract: The subject matter of the present disclosure are agents for stabilizing keratin fibers, more particularly human hair, containing in a cosmetic carrier: (a) at least one compound of the formula (I) wherein X denotes oxygen (—O—), sulfur (—S—) or a grouping —NR5—.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: February 18, 2020
    Assignee: Henkel AG & Co. KGaA
    Inventors: Antje Gebert-Schwarzwaelder, Ralph Nemitz, Astrid Kroos
  • Long-acting non-aqueous injectable formulations and use thereof
    Patent number: 10555899
    Abstract: Provided herein are long-acting, non-aqueous pharmaceutically acceptable compositions of active ingredients for subcutaneous injection, in particular analgesics such as buprenorphine.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: February 11, 2020
    Assignee: Piedmont Animal Health, LLC
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea Erxleben
  • Method and system for adding sensory conditioning cues in a pharmacotherapeutic regimen
    Patent number: 10556011
    Abstract: A method and system for administering pharmaceutical agents to a subject is provided. The system includes a course of treatment regimen, which includes a prescribed order of medicine amounts for periodic administration to the subject in the prescribed order. The amount of medicine includes a dose of at least one active pharmacological agent (APA) and an amount of at least one non-active pharmacological agent (NPA). The NPA provides at least one non-visual sensory cue. The dosage amounts of the APA contained within the amounts of medicine periodically administered in the prescribed order are varied within the course of treatment regimen, and the amount of the NPA contained within the amounts of medicine periodically administered in the prescribed order are held constant within the course of treatment regimen.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: February 11, 2020
    Inventors: Joshua D. Levine, Robert A. Levine
  • Chemoprevention of colorectal cancer
    Patent number: 10555956
    Abstract: In the present invention, a new combination is disclosed comprising (i) 5-aminosalicylic acid (5-ASA) or a derivative thereof, or a pharmacologically acceptable salt thereof, and (ii) a group D vitamin, a derivative thereof, a metabolite or analogue, for use in the prevention and/or treatment of colorectal cancer (CRC). A further aspect of the invention is directed to pharmaceutical compositions comprising said combination together with at least one physiologically acceptable excipient and the use thereof in the prevention and/or in the treatment of the colorectal cancer.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: February 11, 2020
    Assignee: SOFAR SPA
    Inventors: Alexis Grande, Fabrizio Ferrarini, Sandra Parenti
  • Compositions of gallium (III) complexes for oral administration
    Patent number: 10548849
    Abstract: The present invention relates to dosage forms of gallium complexes suitable for oral delivery and methods of preparation thereof. Such dosage forms are useful for the treatment of diseases, including, but not limited to, cancer.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: February 4, 2020
    Assignee: Altum Pharmaceuticals Inc.
    Inventors: Rickey Roy Rhinebarger, Gina G. Stetsko
  • Compositions for treating infections
    Patent number: 10537519
    Abstract: The present invention relates to compositions and in particular to compositions for treating a skin or mucosal membrane infection.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: January 21, 2020
    Assignee: Sci-Chem International Pty Ltd
    Inventor: Aiyaz A Shah
  • Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers
    Patent number: 10531663
    Abstract: The present invention relates to an ophthalmic solution comprising 0.00001 to 10.0 weight percent of a simple saccharide, at least 0.00001 weight percent of a preservative, and not more than about 0.2 percent by weight chloride. The simple saccharide is chosen from the group consisting of: inositol; mannitol; sorbitol; sucrose; dextrose; glycerin; propylene glycol; ribose; triose; tetrose; erythrose; threose; pentose; arabinose; ribulose; xylose; xylulose; lyxose; hexose; allose; altrose; fructose; galactose; glucose; gulose; idose; mannose; sorbose; talose; tagatose; adlose; ketose; heptose; sedoheptulose; monosaccharides; disaccharides; sugar alcohols; xylitol; and polyol.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: January 14, 2020
    Assignee: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • Topical sanitizing formulations and uses thereof
    Patent number: 10524997
    Abstract: Several embodiments disclosed herein relate to formulations having antimicrobial and/or sanitizing effects, and uses of the same. In particular, the formulations and methods of using same provide, in several embodiments, an immediate and a persistent antimicrobial effect against a broad spectrum of microorganisms.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: January 7, 2020
    Inventors: Jesse Cozean, Colette Cozean, Susan Goldsberry
  • Compositions comprising apomorphine and organic acids and uses thereof
    Patent number: 10525134
    Abstract: The present invention provides stable liquid or semi-solid pharmaceutical compositions of apomorphine, more particularly composition comprising apomorphine and an organic acid, which are useful in treatment of neurological or movement diseases or disorders, e.g., Parkinson's disease, or conditions associated therewith.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: January 7, 2020
    Assignee: NeuroDerm, Ltd.
    Inventors: Oron Yacoby-Zeevi, Mara Nemas
  • Bionanocomposite synthesis for would healing
    Patent number: 10525147
    Abstract: A method for treating a burn, lesion, lacuna, or wound comprising contacting the burn, lesion, or wound with a chitosan-functionalized silica sphere (“CHI-HSS”). Chitosan-functionalized silica spheres and pharmaceutical compositions containing them.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: January 7, 2020
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ayhan Bozkurt, Abdulhadi Baykal
  • Mast cell inhibition in diseases of the retina and vitreous
    Patent number: 10517839
    Abstract: This application discloses methods for treating or preventing an ophthalmic retinal vascular permeability, angiogenic or fibroproliferative disease, disorder or condition that involve administering to a patient in need thereof a composition that can inhibit mast cell migration into the vitreous or the retina, mast cell proliferation in the vitreous or the retina, or mast cell secretion into the vitreous or the retina.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: December 31, 2019
    Assignee: Cornell University
    Inventors: Randi B. Silver, Nathan O'Connor
  • Topical brimonidine tartrate ophthalmic solution
    Patent number: 10517869
    Abstract: The present invention provides an aqueous ophthalmic composition comprising an alpha-2 adrenergic receptor agonist and a non-ionic cellulosic polymer, the solution having a pH less than 6.5. The present invention also provides an aqueous ophthalmic composition comprising an alpha-2 adrenergic receptor agonist and a benzododecinium halide. Also provided are methods of manufacture, use and method of reducing intraocular pressure in the patient in need thereof.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: December 31, 2019
    Assignee: SENTISS PHARMA PRIVATE LIMITED
    Inventors: Mandar V. Shah, Deepak Bahri
  • Sunscreen compositions with natural waxes for improved water resistance
    Patent number: 10517814
    Abstract: A sunscreen composition having improved water resistance comprising (i) a sunscreen active agent; (ii) a water resistant agent comprising a natural wax having a Damping Factor of less than 1.0 in a linear viscoelastic range at body temperature; and (iii) an emulsifier or a surfactant capable of stabilizing an emulsion of components (i) to (iii), wherein said sunscreen composition maintains at least 75%, preferably at least 85%, and most preferably at least 99%, of its static SPF after water immersion for 4 hours.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: December 31, 2019
    Assignee: EDGEWELL PERSONAL CARE BRANDS, LLC
    Inventors: Hui-Ing Donna Hwang, Alexander Naranjo, Patricia Lynn Scott
  • Ferment extract of and cosmetic use thereof
    Patent number: 10512603
    Abstract: A ferment extract from a bacterial strain the Eupenicillium crustaceum species useful in the cosmetic treatment and/or care of the skin, mucous membranes, hair and/or nails and cosmetic uses of same.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: December 24, 2019
    Assignee: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: Núria Almiñana Domènech, Albert Soley Astals, Nuria García Sanz, Gemma Mola Llobera, José Darias, Mercedes Cueto
  • Solid oral formulation of fenretinide
    Patent number: 10512619
    Abstract: Amorphous solid dispersions suitable for oral delivery comprising fenretinide or an analog thereof and at least one matrix polymer, and processes for making the dispersions, are disclosed. Also disclosed are solid oral formulations comprising the amorphous solid dispersions, as well as uses thereof for the prevention and/or treatment of diseases or conditions treatable by fenretinide, including but not limited to cancers, conditions associated with a lipid imbalance, cystic fibrosis, osteoporosis, conditions associated with inflammation or opportunistic infections, and other diseases such as diabetes, obesity, dry-form age-related macular degeneration.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: December 24, 2019
    Assignee: LAURENT PHARMACEUTICALS
    Inventors: Aimesther Betancourt, Marc Lemieux, Roch Thibert
  • Reflective skin-spread composition
    Patent number: 10500143
    Abstract: A reflective skin-spread composition is provided. The composition comprises 80 to 90 w/w % reflective glass microspheres, and 10 to 20 w/w % carrier medium. The reflective glass microspheres have an average diameter of 30 to 80 microns. The carrier medium comprises an emollient ester, a plant emollient, a binder/stabilizer, and a water-resistant film-forming agent. The composition comprises the emollient ester at 3 to 6 w/w %, the plant emollient at 2 to 5 w/w %, the binder/stabilizer at 3 to 6 w/w %, and the water-resistant film-forming agent at 1 to 4 w/w %. An applicator for applying the composition to a surface also is provided. A method of enhancing visibility of a person comprising a step of applying the composition to an exposed skin surface of the person also is provided.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: December 10, 2019
    Assignee: ROAD WISE LLC
    Inventor: John F. Kulbis
  • Totally-mesoporous zirconia nanoparticles, use and method for producing thereof
    Patent number: 10501331
    Abstract: The present invention relates to novel totally-mesoporous zirconium oxide nanoparticles as well as a sol-gel synthesis process thereof which include an innovative nanoparticles purification step. Said nanoparticles are characterized by a totally-mesoporous structure i.e. a distribution of pores within the so-called the mesoporous range uniformly distributed throughout the entire nanoparticle volume. Furthermore, said nanoparticles are non-cytotoxic and present a high surface area, which make particularly suitable in both biomedical and industrial applications (e.g. drug delivery, heavy metals ion sequestration). The manufacturing method is simple and advantageously allows for high control over the shape and diameter of the nanoparticles as well as over the nanoparticles pores.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: December 10, 2019
    Assignee: BRENTA S.R.L.
    Inventors: Gabriele Sponchia, Alvise Benedetti, Pietro Riello
  • Method of treating cancer with a two-component anti-cancer composition
    Patent number: 10494392
    Abstract: Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamate ligands are connected by Au(I)—Au(I) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: December 3, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Anvarhusein A. Isab, Muhammad Altaf, Adam Ahmed Abdallah Seliman
  • (20S)-1-?,25-dihydroxy-24,24-difluoro-19-nor-vitamin Danalogs and their pharmaceutical uses
    Patent number: 10494337
    Abstract: Disclosed are 1?,25-dihydroxy-24,24-difluoro-2-methylene-19-nor-vitamin D analogs and their pharmaceutical uses. These new vitamin D analogs are 19-nor-vitamin D analogs having two fluorine atom substitutions at the 24 position (C-24) in the side chain and optionally having a 2-methylene substituent.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: December 3, 2019
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Hector F. DeLuca, Agnieszka Flores, Lori A. Plum, Hazel Holden, James Thoden