Abstract: The present application is directed to regimens, methods of treatment, and compositions for the treatment of acne in a subject suffering therefrom.
Abstract: Pharmaceutical compositions containing a fluoroquinolone antibiotic drug are disclosed. The compositions exhibit improved homogeneity, improved bioavailability, lower turbidity or a combination thereof. The composition can be use as otic or nasal compositions, but are particularly useful as ophthalmic compositions.
Type:
Grant
Filed:
January 18, 2013
Date of Patent:
August 25, 2015
Assignee:
Alcon Pharmacueticals Ltd.
Inventors:
Inmaculada Campins, Nuria Jiménez, Roman Vidal, Nuria Carreras, Carmen Martinez, Francisco Javier Galàn
Abstract: A method for increasing immune responses of a human patient infected with HIV, involving contacting the T-cells, in vitro or in vivo, with an organic compound at a concentration effective to cause T-cell proliferation, but below an amount that causes detectable cytotoxicity.
Type:
Grant
Filed:
January 18, 2000
Date of Patent:
January 7, 2003
Assignee:
Trustees of Tufts College
Inventors:
Brigitte T. Huber, Tracy Schmitz, Robert Underwood
Abstract: The present invention is directed to compositions that inhibit the nonenzymatic glycation of albumin,, as well as methods of using compounds that inhibit albumin glycation for the treatment of glycation-related pathologies.
Abstract: A preparation suitable for sustained and extended corneal analgesia and for repeated administration consisting of subanesthetic concentrations of lidocaine. A method for corneal analgesia by administering to a patient an ophthalmic analgesic solution containing lidocaine in subanesthetic 0.4% concentration.
Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
Type:
Grant
Filed:
February 6, 2001
Date of Patent:
February 5, 2002
Assignee:
Alcon Manufacturing, Ltd.
Inventors:
Thomas R. Dean, Jesse A. May, Verney L. Sallee, Louis Desantis, Jr.
Abstract: Photodynamic therapy to prevent secondary cataracts is effected using photosensitizers such as green porphyrins as photoactive agents to destroy remnant lens epithelial cells.
Type:
Grant
Filed:
March 27, 2000
Date of Patent:
June 19, 2001
Assignees:
QLT, Inc., The University of British Columbia, Ciba Vision Opthalmics
Inventors:
Howard E. Meadows, Danielle Wenkstern, David R. Mallek, Marcello Nick Bussanich, Anna M. Richter, Julia G. Levy, Claude A. A. Hariton, Gustav Huber, Jack Rootman
Abstract: The present invention relates to the use of an ester of inositoltrispbosphate for the preparing of a medicament effective against retroviral diseases.
Abstract: The invention relates to a method of enhancing vascularization and growth of neural grafts in warm-blooded animals, especially man, comprising administering an effective amount of the nimodipine, a calcium channel blocker, having the formula 1,4-dihydro-2,6-dimethyl-4-(3'-nitrophenyl)-pyridine-3-(.beta.-methoxyethy l ester)-5-(isopropyl ester) to the animals to achieve such enhancement and growth. The method enhances the survival rate of transplantations.
Abstract: A method for the topical treatment of glaucoma or ocular hypertension which comprises contacting the surface of the eye with a composition consisting essentially of an effective intraocular pressure reducing amount of a mixture of (a) an adrenergic agonist selected from the group consisting of epinephrine, dipivalylepinephrine, norepinephrine, phenylephrine, clonidine, isoproterenol, salbutamol, metaproterenol and terbutaline, and (b) a phosphodiesterase inhibitor selected from the group consisting of isobutylmethylxanthine, theophyllamine, Rolipram and RO-2017624, in an ophthalmically compatible carrier.
Abstract: The present invention is directed to the use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure and compositions suitable for this case.
Type:
Grant
Filed:
February 6, 1989
Date of Patent:
May 21, 1991
Assignee:
Sanofi
Inventors:
Jean Gubin, Pierre Chatelain, Marcel Descamps, Dino Nisato, Henri Inion, Jean Lucchetti, Jean-Marie Mahaux, Jean-Noel Vallat, Gerard Le Fur