Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
Type:
Grant
Filed:
February 5, 2002
Date of Patent:
April 20, 2004
Assignee:
Alcon Manufacturing, Ltd.
Inventors:
Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke
Abstract: Treatment with a cyclooxygenase-2 inhibitor and a leukotriene B4 receptor antagonist is described as being useful in reducing recipient rejection of transplanted organs and for treatment of autoimmune diseases.
Type:
Grant
Filed:
September 12, 2000
Date of Patent:
September 9, 2003
Assignee:
G.D. Searle & Co.
Inventors:
Susan A Gregory, Peter C Isakson, Gary Anderson
Abstract: The present invention relates to methods and compositions comprising a very low dose of cyclobenzaprine or metabolite thereof for preventing and treating sleep disturbances and illnesses manifested with sleep dysfunction including fibromyalgia syndrome, chronic fatigue syndrome, sleep disorders, psychogenic pain disorders or chronic pain syndromes or symptoms thereof. The present invention further relates to methods and compositions for treating sleep disturbances, chronic pain or fatigue in humans suffering from fibromyalgia syndrome, chronic fatigue syndrome, sleep disorders, psychogenic pain disorders, chronic pain syndromes using a very low dose of cyclobenzaprine.