Abstract: The present invention generally relates to emulsions, and more particularly, to multiple emulsions. In one aspect, multiple emulsions are formed by urging a fluid into a channel, e.g., by causing the fluid to enter the channel as a “jet.” Side channels can be used to encapsulate the fluid with a surrounding fluid. In some cases, multiple fluids may flow through a channel collinearly before multiple emulsion droplets are formed. The fluidic channels may also, in certain embodiments, include varying degrees of hydrophilicity or hydrophobicity. As examples, the fluidic channel may be relatively hydrophilic upstream of an intersection (or other region within the channel) and relatively hydrophobic downstream of the intersection, or vice versa. In some cases, the average cross-sectional dimension may change, e.g., at an intersection. For instance, the average cross-sectional dimension may increase at the intersection.

Abstract: Lignocellulosic materials can be press formed into mats using heated carbon dioxide and a phenol formaldehyde resin. Employing this method allows for a reduction or even elimination of the use of steam. The carbon dioxide, along with other gases may be recovered for recycle or disposal thus reducing the environmental footprint the process.

Abstract: The present invention provides novel, serum-stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles. More particularly, the present invention provides serum-stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (e.g., one or more interfering RNA molecules), methods of making the SNALP, and methods of delivering and/or administering the SNALP (e.g., for the treatment of cancer). In particular embodiments, the present invention provides tumor-directed lipid particles that preferentially target solid tumors. The tumor-directed formulations of the present invention are capable of preferentially delivering a payload such as a nucleic acid to cells of solid tumors compared to non-cancerous cells.

Abstract: Provided herein are systems and methods to generate an inhalable vapor in an electronic vaporization device. The vaporization device may generate a vapor with one or more defined characteristics. In some cases, the vapor may have a predetermined aerosol number density and/or a predetermined average aerosol diameter. The vaporization device may generate a vapor from a vaporizable material. In some cases, the vaporizable material may be a liquid material housed in a cartridge. The vaporization device may comprise a rechargeable power storage device.

Abstract: A rotation locking device for use in a row-level sun tracking solar energy collection system includes a housing, a first locking member, a second locking member, and an actuator. The housing is configured to be mounted to a pile and configured to permit a torque tube to extend through the housing. The first locking member has a plurality of circumferentially spaced projections attached to and rotatable with the torque tube. The second locking member is connected to the housing and has a plurality of meeting elements for engaging projections of the first locking member. The actuator is configured to relatively move the first and second locking members between an unlocked position in which the mating elements are disengaged from the projections and a locked position in which the mating elements are engaged with the projections to inhibit rotation of the torque tube with respect to the housing.

Abstract: A computer implemented method of developing computer applications, the method comprising providing to multiple users access, over a network, to information on a data center, with a subgroup of the users having access to a sub-portion of the information that is different from the sub-portion accessible by the remaining tenants of the subgroup; and communicating wide the data center over the network employing a computer system associated with a user of the sub-group to establish application functionality with the sub-portion that may be accessed, over the network, by additional parties authorized by the user. Also disclosed is a machine-readable medium and a data center, both of which facilitate carrying-out the steps of the method.

Abstract: Disclosed are various examples for facilitating distribution of an authentication code to installation of managed applications. An identity certificate is sent to a device by installing a configuration profile on the client device. The configuration profile includes the identity certificate. A management service can also initiate installation of a managed application. The identity certificate can be used to authenticate the client device so that an authentication key can be provided to the managed application.

Abstract: Designs, strategies and methods for forming clamshell shaped batteries are described. In some examples, hermetic seals may be used to seal battery chemistry within the clamshell-shaped batteries. This may improve biocompatibility of energization elements. In some examples, the clamshell form biocompatible energization elements may be used in a biomedical device. In some further examples, the clamshell form biocompatible energization elements may be used in a contact lens.

Abstract: The present disclosure provides a method for controlling a surgical instrument. The method includes connecting a power assembly to a control circuit, wherein the power assembly is configured to provide a source voltage, energizing, by the power assembly, a voltage boost convertor circuit configured to provide a set voltage greater than the source voltage, and energizing, by the voltage boost convertor, one or more voltage convertors configured to provide one or more operating voltages to one or more circuit components.

Abstract: A patient interface device (100) for a pressure support system that includes a fluid coupling conduit (6) and a gas flow generator (4) that produces a flow of breathing gas for a patient. The patient interface device includes: a frame member (120) secured to the patient and an adjustment assembly (110), which includes a body member (130) coupled to the frame member. The body member is fluidly coupled to the fluid coupling conduit. A dial member (160) is coupled to each of the frame member and the body member. When the frame member is under tension and oriented concavely with respect to the dial member, the adjustment assembly is structured to move between a first position and a second position. The frame member exerts a force on the dial member. When the adjustment assembly moves from the first position to the second position, the force increases.

Abstract: Systems and techniques are provided for laminate material bonding. A bonding agent may be applied to a first layer. A second layer may be placed onto the bonding agent on the first layer to form a laminate material. The laminate material may be placed between a first piece of non-compliant material with a first piece of compliant material and a second piece of non-compliant material with a second piece of compliant material. The laminate material may be in contact with the first piece non-compliant material and the second piece of non-compliant material. Pressure may be applied to the laminate material by applying pressure to the first piece of compliant material for a curing time of the bonding agent.

Abstract: A portable device for detecting an analyte associated with a target organic molecule in a liquid and/or solid substance. The device includes a test chamber, a probe, and a sensor. The test chamber contains a liquid volume of test solution including an analytical reagent selected to react with the analyte. The test chamber is sealed by a pierceable membrane wall. The probe is removably positionable to pierce the membrane wall to deposit a sample in the test chamber to form a test mixture with the test solution. The sensor is positioned to detect one or more characteristics of the test mixture in the test chamber indicative of a reaction between the analyte and the analytical reagent.

Abstract: An agricultural implement system is provided that includes a down force cylinder configured to apply a downward force to a row unit, and a depth control cylinder configured to vary a penetration depth of a ground engaging tool of the row unit. The agricultural implement system also includes a valve assembly in fluid communication with the down force cylinder and the depth control cylinder. The valve assembly is configured to automatically adjust the downward force by varying fluid pressure within the down force cylinder based on fluid pressure within the depth control cylinder.

Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.

Abstract: A process for forming a diffusion coating on a substrate is disclosed, including preparing a slurry including a donor metal powder, an activator powder, and a binder, and applying the slurry to the substrate. The slurry is dried on the substrate, forming a slurry layer on the substrate. A covering composition is applied over the slurry layer, and the covering composition is dried, forming at least one covering layer enclosing the slurry layer against the substrate. The slurry layer and the at least one covering layer are heated to form the diffusion coating on the substrate, the diffusion coating including an additive layer and an interdiffusion zone disposed between the substrate and the additive layer.

Abstract: An overfill prevention system for use with a liquid storage tank includes a valve assembly defining a downwardly open liquid discharge opening. A pilot tube is fixed relative to and projects downwardly relative to the valve assembly. The pilot tube defines an internal channel in fluid communication with the valve assembly and a discharge hole spaced downwardly from the valve assembly and in fluid communication with the internal channel and the tank. A float is buoyantly shiftable along the pilot tube between an open position in which the float exposes the discharge hole when liquid within the tank is below a predetermined level, and a closed position in which the float covers the discharge hole when liquid within the tank reaches or exceeds the predetermined level. A flow diverter is disposed between the discharge opening and the float to deflect liquid from the discharge opening away from the float.

Abstract: Variable flow rate fuel ejectors, and methods of use therefore, are disclosed. One variable flow rate ejector includes a primary nozzle, a needle, a motor, a first stop portion, and a first impact-absorbing portion. The primary nozzle is connected to a first inlet chamber to receive a first fluid and transmit a flow of the first fluid through the primary nozzle opening. The needle is disposed to create a gap between the tapered portion of the needle and the primary nozzle opening. The motor is coupled to axially move the needle to vary a size of the gap. The first stop portion delimits the axial movement of the needle in a direction of retraction of the needle from the primary nozzle opening. The first impact-absorbing element is positioned to contact the first stop portion or the needle, respectively, when the needle is fully retracted from the primary nozzle opening.

Abstract: The present invention relates to a method for the production of a diterpene or a glycosylated diterpene, which method comprises: a. fermenting a recombinant microorganism in a suitable fermentation medium, wherein the microorganism comprises one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-Kaurene synthase activity; a polypeptide having ent-Kaurene oxidase activity; and a polypeptide having kaurenoic acid 13-hydroxylase activity and whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol, whereby a diterpene or glycosylated diterpene is produced extracellularly in the fermentation medium; and b. recovering the diterpene or glycosylated diterpene from the fermentation medium.

Abstract: A system and method for requesting, validating, and monitoring hall passes digitally.

Abstract: A drain assembly comprises a shroud, a shank, and a frame. The drain assembly may further comprise a shim with an angled top surface. The frame may have an angled bottom surface. A rotational orientation of the angled top surface of the shim relative to the shank and a rotational orientation of the angled bottom surface of the frame relative to the shank may be independently adjustable, thereby allowing for the top surface of the frame to be both angularly and rotationally adjusted relative to a central axis of the drain assembly independent of the positional height of the shank. The drain assembly may further comprise a cover having bendable tabs. The bendable tabs may be disposed around a periphery of the cover and may be configured to contact an angled inner surface of an upper bowl of the shroud, such that the bendable tabs bend around the frame, thereby locking the cover onto the frame.