Abstract: An artificial reality system is described that renders, presents, and controls user interface elements within an artificial reality environment, and performs actions in response to one or more detected gestures of the user. The artificial reality system captures image data representative of a physical environment and outputs the artificial reality content. The artificial reality system identifies, from the image data, a gesture comprising a motion of a first digit of a hand and a second digit of the hand to form a pinching configuration a particular number of times within a threshold amount of time. The artificial reality system assigns one or more input characters to one or more of a plurality of digits of the hand and processes a selection of a first input character of the one or more input characters assigned to the second digit of the hand in response to the identified gesture.

Abstract: Provided herein are compounds of the Formula I: or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.

Abstract: A bariatric device includes an esophageal member having an esophageal surface that is configured to generally conform to the shape and size of a portion of the esophagus and an anchoring technique anchoring the esophageal member to the portion of the esophagus. The bariatric device includes a cardiac member having a cardiac surface that is configured to generally conform to the shape and size of a portion of the cardiac portion of the stomach and a connector connected with the esophageal member and the cardiac member to cause strain to be applied by the cardiac member to the cardiac portion of the stomach. The strain applied by the cardiac member to the cardiac portion of the stomach causes satiety in the absence of food. The connector is adapted to pass through the gastroesophageal junction while leaving a continuous portion of the gastroesophageal junction substantially unrestrained.

Abstract: Various examples are described for defining automations for client devices enrolled with a management service. A computing environment can cause one or more user interfaces to be shown in a display of an administrator device that include at least one field for generating an automation that includes a trigger, a condition, and an action to automatically be performed when the condition is satisfied. The trigger defines a time at which the management service compares the condition to device profiles generated for client devices enrolled with the management service. The user interface can forecast a number of client devices that will be affected or subject to an automation, and can display results of the automation as it is executed in real time.

Abstract: Aspects and embodiments of the present invention generally include a device for patient self-administration of a prescribed medication. The total quantity of doses to be contained in the device, the quantity of prescribed medication comprising each individual dose, and the dosing schedule, collectively referred to as prescription parameters, are determined and controlled solely by a health care provider (HCP) such as the patient's physician. In accordance with a prescribed dosing schedule, the device makes available for administration the precise quantity of prescribed medication constituting an individual dose.

Abstract: Aerial vehicles are assigned to routes within a transportation network based on a state of charge, state of power, and/or state of health for the aerial vehicle. Such aspects can be modeled based on one or more statistical models and/or machine-learned models, among other examples. As another example, an energy budget is used to ensure that the state of charge, state of power, and/or state of health of the aerial vehicle during and/or after traveling the route remains within the energy budget. A payload is assigned to a route and an associated aerial vehicle, thereby generating an itinerary. In examples, the itinerary is validated by the aerial vehicle to ensure that the aerial vehicle is capable of traveling the route with the payload. In examples where the aerial vehicle rejects the itinerary, the itinerary is assigned to another aerial vehicle and a new itinerary is identified for the aerial vehicle.

Abstract: An artificial reality system is described that renders, presents, and controls user interface elements within an artificial reality environment, and performs actions in response to one or more detected gestures of the user. In one example, an artificial reality system comprises an image capture device configured to capture image data representative of a physical environment; a head-mounted display (HMD) configured to output artificial reality content; a gesture detector configured to identify, from the image data, a gesture comprising a motion of two fingers from a hand to form a pinching configuration and a subsequent pulling motion while in the pinching configuration; a user interface (UI) engine configured to generate a UI input element in response to identifying the gesture; and a rendering engine configured to render the UI input element as an overlay to at least some of the artificial reality content.

Abstract: The present disclosure provides, in various embodiments, technology for configuration of a digital twin for a building or other facility via BIM (Building Information Modelling) data extraction and asset register mapping. This is particularly relevant for the purposes of increasing efficiency and reducing risks of data errors in the context of configuring a digital twin interface for a building. Also described herein is technology configured to provide data flow management for defining of digital records representing building infrastructure based on building information modelling data. This is particularly relevant for the purposes of increasing efficiency and reducing risks of data errors in the context of configuring a digital twin interface for a building.

Abstract: A video encoder encodes a video into a data stream, the video encoder being configured to vary a granularity at which a Quantization Parameter—QP—is applied depending on an association of frames of the video to temporally hierarchical layers at which the video is encoded into the data stream. The technology also concerns a respective decoder, a respective method for encoding and decoding, and a computer program for implementing the methods.

Abstract: A request to read data from a location associated with a memory component is received. The request is assigned a first tag, the first tag having a first identifier of a first buffer to store data read from the location. The request to read data is determined to collide with an earlier request to write data to the location. The earlier request is assigned a second tag, the second tag having a second identifier of a second buffer to store data to write to the location. An attempt to lock the second tag and the second buffer for the request to read data is made. The request to read data is fulfilled from the second buffer in response to a successful attempt to lock the second tag and the second buffer.

Abstract: Embodiments of the present systems and methods may provide techniques that provide enrichment of semantic graphing with relations that can enable a higher resolution of the semantic relationships and enable a more accurate prediction of new relations in the graph. For example a method for drug discovery and drug repositioning may comprise generating semantic relationships, at the computer system, based on data relating to a plurality of aspects of drugs and pharmaceutical compounds, generated semantic relationships represented in the form of a semantic graph, learning, at the computer system, new relations among the semantic relationships in the semantic graph using Denoising Autoencoders to process the semantic graph, and generating, at the computer system, predictions for drug discovery and drug repositioning based on the semantic relationships, including the newly found relations.

Abstract: A water heater may be configured to detect a possible main gas valve non-closure condition in which the sensed water temperature continues to rise while a thermopile signal reaches a stable state. When the possible main gas valve non-closure condition is detected, the controller may be configured to toggle the main gas valve ON and determine whether the thermopile signal from the thermopile changes from the stable state or not by at least a predetermined amount.

Abstract: The present disclosure relates to thin film coating processes, compositions so formed and intermediates used and formed therein using multiple coating stations and multiple drying stations in the thin film coating processes.

Abstract: A Register Transfer Level (RTL) representation is recovered from a netlist representing an integrated circuit (IC). The netlist is converted to a graph comprising nodes belonging to a set of node types and edges connecting the nodes. The set of node types includes an instance node type representing an electronic component and a wire node type representing signal transfer between components. The graph is converted to a standardized graph by replacing subgraphs of the graph with standardized subgraphs. An RTL representation of the standardized graph is generated by operations including building signal declarations in a hardware description language (HDL) from the wire nodes of the standardized graph and building signal assignments in the HDL from instance nodes of the standardized graph.

Abstract: A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of a user, and a tube configured to extend from the housing for insertion into the anatomy of the user. The tube includes a plurality of conduits defined within the tube. The plurality of conduits include a fluid delivery conduit configured to facilitate a fluidic connection between a fluid source and the anatomy of the user, and one or more conduits configured to accommodate a plurality of electrodes for determining a physiological characteristic of the user.

Abstract: Because not all companies register or obtain barcodes (or other encodings or identifiers) from a single, consistent source, and because different companies can be associated with the same barcode at different times, there can be multiple products associated with a specific barcode. If a user requests information associated with a specific barcode, information associated with the user or request can be used to attempt to determine the associated product if more than one matching product is uncovered. In some embodiments, a location of a user device at approximately a time of the request can be used to attempt to determine the appropriate product, such as if the user is in a store that only offers one of the potential products. Other information can be used as well, such as past locations, purchase history, viewing patterns, and the like.

Abstract: Provided herein, inter alia, are methods and compounds of formula (I) for inhibiting K-Ras and for treating cancer.

Abstract: A method of cropping an image containing an image of a human face includes detecting a region occupied by the image of the human face within the image, evaluating a plurality of candidate crops of the image, and selecting a crop of the image from the plurality of candidate crops of the image based on the results of the evaluation. The evaluating step includes applying a penalty to a candidate crop of the image in which the detected region occupied by the image of the human face is excluded or only partially included.

Abstract: The present disclosure provides a transgenic corn comprising event MON87403 that exhibits increased grain yield. The disclosure also provides cells, plant parts, seeds, plants, commodity products related to the event, and DNA molecules that are unique to the event and were created by the insertion of transgenic DNA into the genome of a corn plant. The disclosure further provides methods for detecting the presence of said corn event nucleotide sequences in a sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said corn event.