Publication number: 20240199546
Abstract: Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein m, n, R2, R3, R5, R6, R7, R8, R9, R10, R11a, R11b, and X are as defined elsewhere herein. Also provided herein are methods of preparing compounds of formula (II). Also provided herein are methods of inhibiting SLC6A19 and methods of treating a SLC6A19-mediated disease, disorder, or condition in an individual in need thereof.
Type:
Application
Filed:
October 11, 2023
Publication date:
June 20, 2024
Inventors:
Jennifer PITZEN, Maximiliano De La Higuera Macias, Nicole Cooper, Christopher Joseph Sinz, Patrick Sang Tae Lee, Jessica Wahlers, Nathan Fastman, Christos Tzitzilonis, David John Morgans, JR., Yuxi Liu, Kevin Mellem, Alexander Wayne Schammel, Chris Ziebenhaus, Adam Neil Reid, Caleb Henry Karmel