Abstract: The invention provides methods and materials related to a gene expression-based survival predictor for diffuse large B cell lymphoma (DLBCL) patients.

Abstract: One embodiment of a therapeutic composition comprises one or more APLs, e.g., APL A12, for treating diseases or disorders related to arthritis, including rheumatoid arthritis. Another embodiment includes a method of inducing a Th2-type cytokine secretion profile in a mammal, including administering a therapeutic amount of A12 analog peptide. Another embodiment includes a method for generating functional T regulatory cells, the method including administering a therapeutic amount of APL A12 to a RA patient.

Abstract: Methods for increasing urine flow are disclosed, comprising administration of an effective amount of GLP-1, an exendin, or an exendin or GLP-1 agonist. Methods for increasing urinary sodium excretion and decreasing urinary potassium concentration are also disclosed. The methods are useful for treating conditions or disorders associated with toxic hypervolemia, such as renal failure, congestive heart failure, nephrotic syndrome, cirrhosis, pulmonary edema, and hypertension. The present invention also relates to methods for inducing an inotropic response comprising administration of an effective amount of GLP-1, an exendin, or an exendin or GLP-1 agonist. These methods are useful for treating conditions or disorders that can be alleviated by an increase in cardiac contractility such as congestive heart failure. Pharmaceutical compositions for use in the methods of the invention are also disclosed.

Abstract: Provided is a turbine having a first impingement-type turbine portion and a second impingement-type turbine portion integrated into a rotatable disk, wherein the first impulse-type turbine portion has a plurality chutes and a high contact surface for contacting a working fluid and wherein the second impingement-type turbine portion has a plurality of ducts in an upstream rotor and a plurality of vanes in downstream rotor.

Abstract: A technique facilitates the monitoring of elongate structures. An elongate structure is combined with an optical fiber deployed along the structure. An interrogation system is operatively joined with the optical fiber to input and monitor optical signals to determine any changes in parameters related to the structure.

Abstract: A vent for a roof includes a body having an inner surface facing the roof, an outer surface, first and second opposing ends and first and second opposing sides. First and second edge portions are disposed at or about the first and second sides, respectively, and include a plurality of openings for the passage of air. A plurality of protrusions extend outwardly from the inner surface of the body. A plurality of elongated resilient members extend longitudinally between the first and second ends of the body and cooperate with the protrusions. At least a portion of each of the elongated resilient members extends beyond a bottom edge of the vent and is compressed against the exterior surface of the roof, in order to substantially fill in and seal spaces between the exterior surface of the roof and the at least one vent.

Abstract: The method and web application is for users of cellular mobile devices to keep track of their personal finances while the user is mobile. The web application is accessed via internet capable mobile devices to record financial transactions such as debit, credit, and cash transactions at the point of the transaction, to avoid lost or forgotten transactions and avoid bank overdraft charges. The method and web application will provide five sets of tools as a service to customers. These sets are: Account ledger, account balancing tools, bill and debt management, budgeting tools, and user management tools.

Abstract: A transaxle can include a housing, a low range gear assembly, and a differential gear assembly. The low range gear assembly can be mounted in the housing and can include a ring gear, a carrier, planet gears, a sun gear, and a clutch. The ring gear, the carrier, and the sun gear can be mounted in the housing. The planet gears can be rotatably mounted on the carrier and can engage the ring gear while the sun gear can engage the planet gears. The clutch can be selectively movable between a first position where the clutch engages each of the sun gear and the carrier and permits rotation of the sun gear relative to the housing and a second position where the clutch engages each of the sun gear and the housing and rotationally fixes the sun gear relative to the housing.

Abstract: The present disclosure relates to memory arrays with read reference voltage cells. In particular the present disclosure relates to variable resistive memory cell apparatus and arrays that include a high resistance state reference memory cell and a low resistance state reference memory cell that provides a reliable average reference voltage on chip to compare to a read voltage of a selected memory cell and determine if the selected memory cell is in the high resistance state or low resistance state. These memory arrays are particularly suitable for use with spin-transfer torque memory cells and resolves many systematic issues related to generation of a reliable reference voltage.

Abstract: A system for determining radio frequency identification (RFID) performance includes a radio frequency identification (RFID) system comprising at least one antenna and at least one reader configured to receive an RF indication from an RFID tag, the RFID system configured to provide RFID data and an RFID time stamp relating to the at least one antenna. The system also includes a motion capture video system comprising at least one camera and a processing system. The motion capture video system also includes a recognizable element located proximate to the RFID tag, the motion capture video system also configured to provide position data relating to the position of the recognizable element and a motion capture time stamp.

Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.

Abstract: A composition and method for treatment of osteoarthritis is disclosed. The composition includes at least one soluble injectable biocompatible carrier having a viscosity within prescribed limits and an amount of a calcium-channel blocker chosen in relation to the viscosity of the carrier. The concentration of the calcium-channel blocker in the joint synovial fluid is controlled according to the invention whereby effective treatment of osteoarthritis is provided.

Abstract: An apparatus and method for automatically controlling a drivetrain coupled to at least one drive wheel of a vehicle can include providing a first assembly including a low range drive ratio and a high range drive ratio. An electronic control unit can be configured to receive information from at least one sensor located on the vehicle and to provide an output signal based on the information. An actuator mechanism can be provided and configured to cause the first assembly to operate at a selected one of the low range drive ratio and the high range drive ratio based on instructions from the control unit. Separate algorithms can be provided to determine when to actuate from the high range drive ratio to the low range drive ratio and vice versa.

Abstract: An absorbent article may comprise a first zone comprising graphics and a second zone comprising graphics, wherein the first and second zones have different elastic properties. Further, the absorbent article may comprise a first absorbent article component and a second absorbent article component having substantially different elastic properties, wherein the first absorbent article component comprises an elastomer. Additionally, the absorbent article may comprise a third absorbent article component overlapping the first and second absorbent article components, wherein the third absorbent article component comprises graphics on at least the portions which overlap the first and second absorbent article components.

Abstract: A computer-implemented method can include accessing a micro-blog to retrieve a real-time copy of the micro-blog thread and delivering the real-time copy of the micro-blog thread for display in an e-mail message.

Abstract: A process used during manufacture of printed circuit boards comprises protecting metal pads and/or through-holes to provide a tarnish-resistant and solderable coating. In the method, the pads and/or through-holes are bright-etched, metal plated, preferably by an immersion process, and treated with a tarnish inhibitor. The tarnish inhibitor may be incorporated into the immersion plating bath. The metal plating is usually with silver or bismuth and the pads and/or through-holes comprise copper.

Abstract: A fluid filtration system is disclosed comprising a manifold assembly comprising a mounting bracket, an alignment collar connected to the mounting bracket, and a latch assembly moveable with respect to the mounting bracket and alignment collar. The system further comprises a filter cartridge comprising a filter cartridge outer surface and a cartridge latching structure formed on the filter cartridge outer surface to interact with the latch assembly. When the filter cartridge is aligned with the alignment collar and inserted into the manifold assembly, the filter cartridge is (i) latched into the manifold assembly by translating the filter cartridge into the manifold assembly to cause movement of the latch assembly to engage the cartridge latching structure; and (ii) unlatched from the manifold assembly by translating the filter cartridge into the manifold assembly to cause movement of the rotating latch assembly to disengage the cartridge latching structure.

Abstract: The invention relates to a method for sorting, staining or detecting T cells of the immune system using a protein kinase inhibitor.

Abstract: The present invention relates to an overhead transmission line inspection robot and system for inspecting transmission line components and right of way conditions. The overhead transmission line inspection robot includes a communications and control system adapted to control the robot and transmit information and a drive system for propelling the robot along a shield wire to enable inspection over a large area. The robot further includes a camera adapted to inspect right of way and component conditions; a light detection and ranging (LiDar) sensor adapted to measure conductor position, vegetation, and nearby structures; and a global positioning system adapted to identify the robot's position and speed.

Abstract: Method and apparatus are disclosed employing ionizing radiation. for forming lines of ablation or lesions in cardiac tissue to treat atrial fibrillation or other electrophysiological problems with the heart. The apparatus may include a catheter in which the radiation source is advanced hydraulically after the catheter is in place within the heart. Various fixation devices are also disclosed for fixing the location of the catheter within the heart.