Abstract: A system and method of extracting elements from an aqueous stream are described herein. The method includes designing a process to extract at least two elements from the aqueous product stream. The at least two elements have different commercial values. The process is optimized to minimize a cost of extracting the at least two elements and to maximize a value of extracting the at least two elements. The method further includes extracting the at least two elements according to the process.

Abstract: In aspects, the present disclosure provides methods of using multi-tissue organoids bodies including for analyzing the genome or transcriptome of a mammal, analyzing a cellular response to a treatment, determining an effect of a substance, or analyzing a cellular response to a treatment.

Abstract: A method including receiving a request associated with one or more map views associated with a map, transmitting a first set of one or more map views, generating a display of at least one of the first set of one or more map views, receiving a user input associated with the display of the at least one of the first set of one or more map views, and receiving a message associated with the user input. The method may include deter mining a mapping context function based on the received message, the mapping context function being based on one or more user actions associated with one or more features on at least one previously accessed map, determining whether to modify a second set of one or more map views based on the mapping context function, and transmitting the second set of one or more map views.

Abstract: Continuous skin leading edge slats are disclosed. A disclosed example leading edge slat for use with an aircraft includes a single-piece nose skin defining upper and lower external surfaces of the leading edge slat, where the single-piece nose skin is to extend between a fore end and an aft end of the leading edge slat, and a box spar coupled to an inner surface of the single-piece nose skin. The box spar includes lateral walls extending away from the inner surface of the single-piece nose skin. The lateral walls define at least one compartment of the box spar.

Abstract: A no solid bed extruder screw for processing a material to a molten state has a body with a helical thread formed thereon, the thread having pushing and trailing surfaces. The body has an outer surface and extends longitudinally between feed and discharge ends. A channel for receiving the material to be processed is defined between the outer surface of the body and an outer diameter of the thread bounded by the pushing surface and the trailing surface of the thread. A volume of the channel decreases in a plurality of revolutions of the thread in a direction from the feed end to the discharge end. A channel depth between the pushing surface and the trailing surface decreases for a first portion of the channel toward the feed end and increases for a second portion of the channel toward the discharge end.

Abstract: A no solid bed extruder screw for processing a material to a molten state has a body with a helical thread formed thereon, the thread having pushing and trailing surfaces. The body has an outer surface and extends longitudinally between feed and discharge ends. A channel for receiving the material to be processed is defined between the outer surface of the body and an outer diameter of the thread bounded by the pushing surface and the trailing surface of the thread. A volume of the channel decreases in a plurality of revolutions of the thread in a direction from the feed end to the discharge end. A channel depth between the pushing surface and the trailing surface decreases for a first portion of the channel toward the feed end and increases for a second portion of the channel toward the discharge end.

Abstract: Continuous skin leading edge slats are disclosed. A disclosed example leading edge slat for use with an aircraft includes a single-piece nose skin defining upper and lower external surfaces of the leading edge slat, where the single-piece nose skin is to extend between a fore end and an aft end of the leading edge slat, and a box spar coupled to an inner surface of the single-piece nose skin. The box spar includes lateral walls extending away from the inner surface of the single-piece nose skin. The lateral walls define at least one compartment of the box spar.

Abstract: Human pluripotent stem cells are differentiated in vitro into human cortical spheroids (hCS), which contain astrocytes, as well as cortical progenitors and neurons for use in analysis, screening programs, and the like.

Abstract: Provided are methods of modulating neuronal and/or oligodendrocyte survival. The subject methods relate to preventing neuronal and/or oligodendrocyte death or increasing neuron or oligodendrocyte death. Also provided are neuroprotective compositions and neurotoxic compositions. Methods of identifying neurotoxins, methods of identifying neurotoxin inhibitors and methods of identifying neurotoxin conditions in a subject are also provided.

Abstract: C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease.

Abstract: C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including treating and preventing neurodegenerative diseases such as Alzheimer's disease.

Abstract: A helmet for wearing by a sports player comprises: a bubble-shaped body having a hollow interior surrounded by a wall and an opening formed in the wall for inserting a head of the player, and a fastening device for releasably fastening the body to shoulder pads being worn by the player. At least a portion of the wall is formed of a transparent material. Alternate designs are also disclosed, including a helmet constructed of a plastic-coated wireframe, and a non-transparent plastic helmet with a face mask, where in all cases the helmet is rigidly but releasably attached to a chest pad or shoulder pad worn by the player, so that impact forces on the helmet are not transferred to the player's head.

Abstract: Compositions and methods are provided for the purification of astrocytes from biological samples or from in vitro cultures. An advantage of the methods of the invention is the ability to isolate astrocytes in a quiescent state, which allows analysis of the cells in a more natural state.

Abstract: A communication component modifies production of an audio waveform at determined modification segments to thereby mitigate the effects of a delay in processing and/or receiving a subsequent audio waveform. The audio waveform and/or data associated with the audio waveform are analyzed to identify the modification segments based on characteristics of the audio waveform and/or data associated therewith. The modification segments show where the production of the audio waveform may be modified without substantially affecting the clarity of the sound or audio. In one embodiment, the invention modifies the sound production at the identified modification segments to extend production time and thereby mitigate the effects of delay in receiving and/or processing a subsequent audio waveform for production.

Abstract: A plastic melt machine includes a feed screw rotatably mounted in a barrel and driven in rotation about a longitudinal screw axis of the feed screw by a screw drive to plasticize material, and an apparatus for driving a device independently of the feed screw. The device can be any rotatable device associated with the feed screw wherein the device is rotatable about a drive axis and is in fluid communication with the barrel to receive the plasticized material. The drive axis is coaxial with the screw axis. A drive shaft couples the device to the device drive, or to the screw drive through a speed changer, for rotating the device independently of the rotation of the feed screw by the screw drive.

Abstract: C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease.

Abstract: Compositions and methods are provided for the purification of astrocytes from biological samples or from in vitro cultures. An advantage of the methods of the invention is the ability to isolate astrocytes in a quiescent state, which allows analysis of the cells in a more natural state.

Abstract: C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease.

Abstract: C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including treating and preventing neurodegenerative diseases such as Alzheimer's disease.

Abstract: C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including treating and preventing neurodegenerative diseases such as Alzheimer's disease.