Abstract: Apparatus for the manipulating and testing of molecules and in particular of DNA comprising a surface on which the molecule is anchored on multiple points at one end and a paramagnetic bead on which said molecule is anchored on multiple points at its other end, magnetic means for applying a force to the bead, said magnetic means being used to control the stretching and rotation of said bead and molecule, optical magnification means and a camera for the visualisation of said bead, computer means to which the images of the camera are transmitted, said computer means comprising means for analyzing the motions of the bead. A method for the manipulating and testing of molecules and in particular of DNA in which a molecule is anchored at one end to a fixed surface and at its other end to a paramagnetic bead wherein said molecule is anchored on multiple points at each of said ends.

Abstract: This invention relates to a device for recharging a contactless smart card (1) including a recharge kiosk (2) that can have an identifier specific to it and capable of communicating with a contactless smart card (1), a mobile terminal (3) provided with a recharge management program (33) capable of communicating with a recharge server (4) through any type of communication means, means of payment through a communication network and an identity module, and a recharge server (4), characterised in that the mobile terminal (3) includes shape reading means (31) for acquisition of the identifier of the kiosk (2), and its corresponding recharge method.

Abstract: Eukaryotic genomes are duplicated by the activation of multiple bidirectional origins of replication. The replication programs of these cells depend on the temporal and spatial organisation of replication origins throughout the genome. To investigate the replication program in a higher eukaryote, we employed a technique called molecular combing. This technique allows for a quantitative analysis of DNA replication on a genome wide basis. As a model system. Xenopus Laevis sperm chromatin were differentially labelled at successive time points after the beginning of DNA synthesis. Genomic DNA was then extracted and combed on a glass surface. Direct measurements made on the labelled DNA provided a comprehensive analysis of the spatial and temporal organisation of the X. leavis early embryo replication program and revealed that the number of replication origins activated per kilobase increases throughout the period of DNA synthesis.

Abstract: The invention concerns a device containing a personalizable substrate associated to a reader allowing the conditional operation of an electric or electronic appliance after comparison of the data with a memory by an identification and comparison circuit located on an essential part of said appliance. The invention also discloses a method of use under conditional operation of electric or electronic appliances.

Abstract: A device containing a personalizable substrate associated to a reader allowing the conditional operation of an electric or electronic appliance after comparison of the data with a memory by an identification and comparison circuit located on an essential part of said appliance and methods of using the device under conditional operation of electric or electronic appliances.

Abstract: This invention relates to a method for data transmission in a telephone data transmission network (1), from a server (3) to at least one network terminal (11), characterised by the fact that:

Abstract: The method for establishing and managing a trust relationship between an identification module and a radio terminal comprises a terminal authentication step by said identification module done by using authentication means such as a key, said authentication means being provided to at least said identification module by a mobile radio-telephony network at the time of an initialization step or the like or at the time of a so-called updating.

Abstract: To broadcast a set of multimedia contents to mobile terminals located in a geographical zone, a broadcasting server addresses them through a short broadcast message. A geographical zone is defined as a set of cells of a mobile telephony network. The short message is received by all the mobile terminals present in these cells. The reception of this short message prompts the connection of this terminal to the broadcasting server for the retrieval of a set of multimedia contents associated with the short message. The retrieval is done in either WAP/GPRS mode or voice mode.

Abstract: The present invention relates to a process and a system for subscription sharing between a plurality of radiotelephone terminals (20a to 20e), with a unique telephone number associated with the plurality of terminals. In particular, the process is characterised in that it includes a first step wherein a manager shares out a period of access to a radiotelephony network, under the subscription, into time slots and wherein the manager allocates specific time slots to each terminal (20a to 20e), the time slots allocated to the different terminals (20a to 20e) not overlapping, a second step wherein the time slots specific to each terminal (20a to 20e) are transmitted (53a, 53b) from one or more synchronisation servers (1) to each terminal (20a to 20e), and a third step wherein the specific time slots are stored in the memory of each terminal (20a to 20e) to which said time slots have been allocated. The invention also relates to a system allowing the process to be implemented.

Abstract: The present invention relates to a process for managing context data (40) for a multilateral and multimode operation, using several software configurations allowing surfing on at least one network in order to access to a content provider service, representing information which is either specific to a content provision session via computer communication, through at least one information network (1), between at least one digital data processing device, called client terminal (30 to 35), and at least one content provider information system (2), or specific to the user of said client terminal(s), or specific to a combination of these elements, this context data (40) being stored outside the content provider information system(s) (2) and at the request of said provider system(s) (2), characterised in that it comprises at least one step wherein this context data is stored in storage means by one or more computer agents, called context proxies (4), in storage means independent of the client terminal(s) and of the so

Abstract: The invention concerns a method for detecting or locating one or several genes of one or several specific A DNA sequence or one or several molecules reacting with DNA on a B DNA characterised in that it consists in: (a) fixing and combing a certain amount of said B DNA on a combing surface; (b) reacting the product of the B combing with one or several probes, linked with the gene(s) or specific A DNA sequences, or with the molecules capable of reacting with DNA; (c) extracting information corresponding to at least one of the following categories: (1) the position of the probes, (2) the distance between the probes, (3) the size of the probes (the total sum of sizes for quantifying the number of hybridised probes) for determining therefrom the presence, the location and/or the amount of genes or specific A DNA sequences. This method can be used in particular for the diagnosis of genetic diseases.

Abstract: The present invention discloses a radioactive medical device comprising a radioactive, electroplated substrate coated with at least one layer of polymer and sealed in a jacket layer. The at least one layer of polymer and jacket layer reduce leaching of a radioactive element from the electroplated substrate. The radioactive medical device is useful for radiation therapy of diseased tissue such as cancers and especially malignant tumors.

Abstract: The subject of the present invention is a process for aligning a macromolecule (macromolecules) on the surface S of a support, characterized in that the triple line S/A/B (meniscus) resulting from the contact between a solvent A and the surface S and a medium B is caused to move on the said surface S, the said macromolecules having a part, especially an end, anchored on the surface S, the other part, especially the other end, being in solution in the solvent A.

Abstract: An apparatus for manipulating and testing molecules comprising

Abstract: The subject of the present invention is a process for aligning a macromolecule (macromolecules) on the surface S of a support, characterized in that the triple line S/A/B (meniscus) resulting from the contact between a solvent A and the surface S and a medium B is caused to move on the said surface S, the said macromolecules having a part, especially an end, anchored on the surface S, the other part, especially the other end, being in solution in the solvent A. The subject of the present invention is also a process for detecting, measuring the intramolecular distance of, separating and/or assaying a macromolecule in a sample in which a process of alignment according to the invention is used.

Abstract: Apparatus for the manipulating and testing of molecules and in particular of DNA comprising

Abstract: The invention concerns a method for detecting or locating one or several genes of one or several specific A DNA sequence or one or several molecules reacting with DNA on a B DNA characterized in that it consists in. (a) fixing and combing a certain amount of said B DNA on a combing surface; (b) reacting the product of the B combing with one or several probes, linked with the gene(s) or specific A DNA sequences. or with the molecules capable of reacting with DNA; (c) extracting information corresponding to at least one of the following categories: (1) the position of the probes. (2) the distance between the probes, (3) the size of the probes (the total sum of size quantifying the number of hybridised probes) for determining there from the presence, the location and/or the amount of genes or specific A DNA sequences. This method can be used in particular for the diagnosis of genetic diseases.

Abstract: The subject of the present invention is a process for aligning a macromolecule (macromolecules) on the surface S of a support, characterized in that the triple line S/A/B (meniscus) resulting from the contact between a solvent A and the surface S and a medium B is caused to move on the said surface S, the said macromolecules having a part, especially an end, anchored on the surface S, the other part, especially the other end, being in solution in the solvent A.

Abstract: The invention concerns a method for detecting or locating one or several genes of one or several specific A DNA sequence or one or several molecules reacting with DNA on a B DNA characterised in that it consists in: (a) fixing and combing a certain amount of said B DNA on a combing surface; (b) reacting the product of the B combing with one or several probes, linked with the gene(s) or specific A DNA sequences, or with the molecules capable of reacting with DNA; (c) extracting information corresponding to at least one of the following categories: (1) the position of the probes, (2) the distance between the probes, (3) the size of the probes (the total sum of sizes for quantifying the number of hybridised probes) for determining therefrom the presence, the location and/or the amount of genes or specific A DNA sequences. This method can be used in particular for the diagnosis of genetic diseases.