Abstract: A system, device and method for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where living cells and biologically active molecules flow through a channel that exposes them to electric fields, causing the molecules to be transferred across the cell membrane. The device is structured in a manner that allows precise control of the cells location, motion, and exposure to electric fields within the flow channel device. The method is particularly well suited for the introduction of DNA, RNA, drug compounds, and other biologically active molecules into living cells.

Abstract: The present invention provides a method for treating canine leishmaniasis by immunotherapy.

Abstract: Various embodiments of the present invention are directed to a convertible children's high chair and a booster seat. According to various embodiments, the convertible high chair generally comprises a first child seat supported above a floor by a high chair frame, and a booster seat configured for being removably coupled to first child seat. The booster seat is configured such that, when detached from the high chair's first child seat, it can be used apart from the high chair (e.g., secured to the seating surface of a standard chair or another generally flat support surface). In certain embodiments, the booster seat includes a base surface configured to stably support the second child seat on a separate support surface (e.g., without the need to be attached to or mounted on a separate base or support member).

Abstract: A fluid sampler system includes a fluidic head including a gas aperture capable of communication with a pressurized gas source, a liquid conduit capable of communication with a sample reservoir, and a seal capable of forming a compression seal to the sample reservoir when gas pressure is applied to the sample reservoir through the gas aperture and capable of displacing a portion of the sample through the liquid conduit; and a positioning apparatus capable of positioning the fluidic head and the sample reservoir in communication with one another. A method for providing an aliquot of sample, includes forming a releasable compression seal to a reservoir including a liquid sample; pressurizing the reservoir with compressed gas; displacing an aliquot of the sample from the reservoir; and transferring the displaced aliquot of the sample to a location.

Abstract: A process for manufacturing a MEMS device includes forming a first structural layer of a first thickness on a substrate. First trenches are formed through the first structural layer, and masking regions separated by first openings are formed on the first structural layer. A second structural layer of a second thickness is formed on the first structural layer in direct contact with the first structural layer at the first openings and forms, together with the first structural layer, thick structural regions having a third thickness equal to the sum of the first and the second thicknesses. A plurality of second trenches are formed through the second structural layer, over the masking regions, and third trenches are formed through the first and the second structural layers by removing selective portions of the thick structural regions.

Abstract: A system having a hopper that receives fuel pellets and direct the pellets under gravity feed to an auger that moves the pellets into a firepot inside a cooking chamber of a grill. The system includes a door below the auger that has a closed position that retains fuel pellets in the auger such that the fuel pellets feed to the auger, and has an opened position to allows the pellets to empty from the hopper and away from the auger. A closing mechanism allows a user to selectively open or close the door.

Abstract: Embodiments of a Coriolis-force-based flow sensing device and embodiments of methods for manufacturing embodiments of the Coriolis-force-based flow sensing device, comprising the steps of: forming a driving electrode; forming, on the driving electrode, a first sacrificial region; forming, on the first sacrificial region, a first structural portion with a second sacrificial region buried therein; forming openings for selectively etching the second sacrificial region; forming, within the openings, a porous layer having pores; removing the second sacrificial region through the pores of the porous layer, forming a buried channel; growing, on the porous layer and not within the buried channel, a second structural portion that forms, with the first structural region, a structural body; selectively removing the first sacrificial region thus suspending the structural body on the driving electrode.

Abstract: The present disclosure provides adjustable mandrel hanger assemblies and methods of their use. The adjustable mandrel hanger assembly includes an upper wellhead component, a lower wellhead component comprising a load shoulder, a mandrel hanger with a protrusion disposed on an exterior of the mandrel hanger, a seal assembly, and a height adjustment ring, wherein the height adjustment ring fits securely around a protrusion of the mandrel hanger and wherein a largest exterior diameter of the height adjustment ring is greater than an interior diameter of the load shoulder.

Abstract: Approaches in accordance with various embodiments provide for the presentation of augmented reality (AR) content with respect to optically challenging surfaces. Such surfaces can be difficult to locate using conventional optical-based approaches that rely on visible features. Embodiments can utilize the fact that horizontal surfaces can be located relatively easily, and can determine intersections or boundaries of those horizontal surfaces that likely indicate the presence of another surface, such as a vertical wall. This boundary can be determined automatically, through user input, or using a combination of such approaches. Once such an intersection is located, a virtual plane can be determined whose relative location to a device displaying AR content can be tracked and used as a reference for displaying AR content.

Abstract: A flat spring for firearm magazines has a one-piece unitary body with end half-coils at opposite ends and interior coils in a repeating arrangement between the end half-coils. Each of the interior coils includes an upper half-coil and a lower half-coil, each extending between outer tips on opposite sides of the spring body. Increasing and staggering the half-coil lengths, adjusting the radii of the outer tips and shaped matching the end half-coils and upper and lower half-coils within the magazine housing all contribute to a flat magazine spring that uses all available space within a firearm magazine to effectively reduce the number of coils and material thickness so that the compressed spring height is at its absolute minimum, thereby allowing for maximum space for ammunition.

Abstract: Aqueous composition comprising: from 0.5% by weight to 5% by weight, preferably from 1% by weight to 4% by weight, with respect to the total weight of said aqueous composition, of at least one conductive polymer; from 1% by weight to 100% by weight, preferably from 2% by weight to 10% by weight, more preferably from 15% by weight to 50% by weight, with respect to the total weight of said at least one conductive polymer, of at least one cellulose ether. Said aqueous composition may advantageously be used as a printable ink or printable paste in various techniques such as, for example, screen printing, gravure printing, flexographic printing, spray coating, slot die coating, spin-coating, ink-jet printing. Preferably, said aqueous composition may advantageously be used as a printable paste for screen printing.

Abstract: Users can view images or renderings of items placed (virtually) within a physical space. For example, a rendering of an item can be placed within a live camera view of the physical space. A snapshot of the physical space can be captured and the snapshot can be customized, shared, etc. The renderings can be represented as two-dimensional images, e.g., virtual stickers or three-dimensional models of the items. Users can have the ability to view different renderings, move those items around, and develop views of the physical space that may be desirable. The renderings can link to products offered through an electronic marketplace and those products can be consumed. Further, collaborative design is enabled through modeling the physical space and enabling users to view and move around the renderings in a virtual view of the physical space.

Abstract: Approaches in accordance with various embodiments provide for the presentation of augmented reality (AR) content with respect to optically challenging surfaces. Such surfaces can be difficult to locate using conventional optical-based approaches that rely on visible features. Embodiments can utilize the fact that horizontal surfaces can be located relatively easily, and can determine intersections or boundaries of those horizontal surfaces that likely indicate the presence of another surface, such as a vertical wall. This boundary can be determined automatically, through user input, or using a combination of such approaches. Once such an intersection is located, a virtual plane can be determined whose relative location to a device displaying AR content can be tracked and used as a reference for displaying AR content.

Abstract: An integrated semiconductor device includes: a MEMS structure; an ASIC electronic circuit; and conductive interconnection structures electrically coupling the MEMS structure to the ASIC electronic circuit. The MEMS structure and the ASIC electronic circuit are integrated starting from a same substrate including semiconductor material; wherein the MEMS structure is formed at a first surface of the substrate, and the ASIC electronic circuit is formed at a second surface of the substrate, vertically opposite to the first surface in a direction transverse to a horizontal plane of extension of the first surface and of the second surface.

Abstract: The present disclosure provides adjustable mandrel hanger assemblies and methods of their use. The adjustable mandrel hanger assembly includes an upper wellhead component, a lower wellhead component comprising a load shoulder, a mandrel hanger with a protrusion disposed on an exterior of the mandrel hanger, a seal assembly, and a height adjustment ring, wherein the height adjustment ring fits securely around a protrusion of the mandrel hanger and wherein a largest exterior diameter of the height adjustment ring is greater than an interior diameter of the load shoulder.

Abstract: This disclosure describes techniques for providing instructions when receiving biometric data associated with a user. For instance, a user-recognition device may detect a portion of a user, such as a hand. The user-recognition device may then display a first graphical element indicating a target location for placing the portion of the user above the user-recognition device. Additionally, the user-recognition device may determine locations of the portion of the user above the user-recognition device. The user-recognition device may then display a second graphical element indicating the locations, such as when the locations are not proximate to the target location. Additionally, the user-recognition device may display instructions for moving the portion of the user to the target location. Based on detecting that the location of the portion of the user is proximate to the target location, the user-recognition device may send data representing the portion of the user to a remote system.

Abstract: A microelectromechanical resonator device has: a main body, with a first surface and a second surface, opposite to one another along a vertical axis, and made of a first layer and a second layer, arranged on the first layer; a cap, having a respective first surface and a respective second surface, opposite to one another along the vertical axis, and coupled to the main body by bonding elements; and a piezoelectric resonator structure formed by: a mobile element, constituted by a resonator portion of the first layer, suspended in cantilever fashion with respect to an internal cavity provided in the second layer and moreover, on the opposite side, with respect to a housing cavity provided in the cap; a region of piezoelectric material, arranged on the mobile element on the first surface of the main body; and a top electrode, arranged on the region of piezoelectric material, the mobile element constituting a bottom electrode of the piezoelectric resonator structure.

Abstract: The present invention relates to compositions and buffers for storing engineered extracellular vesicles (EVs), such as exosomes, for extended time periods with maintained stability and function. The present invention allows for both optimized long-term storage and for clinical application of the stored EVs.

Abstract: Users can view images or renderings of items placed (virtually) within a physical space. For example, a rendering of an item can be placed within a live camera view of the physical space. A snapshot of the physical space can be captured and the snapshot can be customized, shared, etc. The renderings can be represented as two-dimensional images, e.g., virtual stickers or three-dimensional models of the items. Users can have the ability to view different renderings, move those items around, and develop views of the physical space that may be desirable. The renderings can link to products offered through an electronic marketplace and those products can be consumed. Further, collaborative design is enabled through modeling the physical space and enabling users to view and move around the renderings in a virtual view of the physical space.