Abstract: An enclosure system attachable to a railway vehicle to protect automobiles in the event of a collision. The enclosure system having an enclosure panel that is actuatable between a deployed configuration and a stowed configuration. A breakaway mechanism configured to allow certain components of enclosure system to release from the railway vehicle in the event of a collision with another railway vehicle to ensure the anticlimbers engage between the railway vehicles to prevent override. The enclosure system having a coupler centering assembly for maintaining a coupler in a forward position when the enclosure is in the deployed configuration.

Abstract: A intranasal device and method for self-administration of a medicament are provided. The intranasal device includes a body, a catheter, a feedback mechanism, and a delivery system. The body has a chamber configured to store the medicament. The body defines a channel that extends from an interior of the body to an exterior of the body. The catheter is configured to be actuated to extend from the body through the channel and is in fluid communication with the chamber. A distal end of the catheter is configured for entry into a nasal passage of a patient. The feedback mechanism is configured to indicate a position of the distal end of the catheter within the nasal passage. The delivery system is configured to deliver the medicament from the chamber into the nasal passage via the catheter.

Abstract: A medicament delivery device may include a blister disposed about a blister axis. A dosing chamber may be configured to receive medicament from the blister and the dosing chamber may be disposed about a chamber axis. A transducer may confront the dosing chamber. The transducer may be configured to aerosolize the medicament when the transducer is activated. The chamber axis may be transverse to the blister axis when the blister is in a dosing position.

Abstract: The present invention provides single-walled carbon nanotube formulations for the delivery of bioactive agents including large polynucleotides encoding therapeutic proteins into hard-to-transfect cells and methods of making such single-walled carbon nanotube formulations.

Abstract: A system for analyzing a coking system comprises a coking system comprising a first coke drum and a second coke drum, and a user device communicatively coupled to a hardware implemented analysis engine. The coking system configured to collect and transmit coke drum data to the hardware implemented analysis engine. The hardware implemented analysis engine is configured to: receive an estimation of an altered life span of the first coke drum relative to a design life span of the first coke drum, analyze an effect of adding an additional coke drum to the coking system based on the altered life span, and provide a result item related to the analysis to the user device. The estimation of the altered life span is based on the coke drum data.

Abstract: Method and apparatus for cleaning an interior volume of an electrical component are provided. The apparatus includes a housing with vacuum pins extending from apertures in the housing. The vacuum pins are arranged and sized to fit through ventilation holes in a chassis of the electrical component. The vacuum pins are individually retractable so that a vacuum pin that encounters a structure in the interior volume of the electrical component does not impede remaining vacuum pins from further entering the volume. A vacuum source is attachable to the housing and applies a vacuum to the interior volume through the vacuum pins.

Abstract: The present invention provides single-walled carbon nanotube formulations for the delivery of bioactive agents including large polynucleotides encoding therapeutic proteins into hard-to-transfect cells and methods of making such single-walled carbon nanotube formulations.

Abstract: A system for analyzing a coking system comprises a coking system comprising a first coke drum and a second coke drum, and a user device communicatively coupled to a hardware implemented analysis engine. The coking system configured to collect and transmit coke drum data to the hardware implemented analysis engine. The hardware implemented analysis engine is configured to: receive an estimation of an altered life span of the first coke drum relative to a design life span of the first coke drum, analyze an effect of adding an additional coke drum to the coking system based on the altered life span, and provide a result item related to the analysis to the user device. The estimation of the altered life span is based on the coke drum data.

Abstract: Systems for analyzing a benefit or detriment of (1) changing an operational condition or parameter, or (2) adding a coke drum to an existing coking system are disclosed. Contemplated systems can increase the cost effectiveness of coking systems by providing valuable analysis data.

Abstract: A method of displaying social media data is provided. The method includes accessing stored social media data from a plurality of social media outlets and obtaining social media data having associated context information. The obtained social media data includes at least first social media data from a first social media outlet and second social media data from a second social media outlet. The method includes providing a user interface that displays representations of the first and second social media data as a function of the context information.

Abstract: A multi-drum coking system wherein at least one drum, and preferably all drums, are fluidly coupled to at least two other drums. The system allows a vapor of one drum to be directed to multiple drums to prevent unnecessary non-productivity of coke drums.

Abstract: Systems for analyzing a benefit or detriment of (1) changing an operational condition or parameter, or (2) adding a coke drum to an existing coking system are disclosed. Contemplated systems can increase the cost effectiveness of coking systems by providing valuable analysis data.

Abstract: A method of displaying social media data is provided. The method includes accessing stored social media data from a plurality of social media outlets and obtaining social media data having associated context information. The obtained social media data includes at least first social media data from a first social media outlet and second social media data from a second social media outlet. The method includes providing a user interface that displays representations of the first and second social media data as a function of the context information.

Abstract: A family of compounds has been developed containing a substantial quantity of boron in solution with other beneficial ingredients that has been heretofore unobtainable. These compounds are named and referred to herein as “Boroncitrates”. The individual Boroncitrates are: boron lithium citrate (BLiCit), boron potassium citrate (BKCit) and boron sodium citrate (BNaCit). These Boroncitrates can be used individually or in combination with one another. Alkali metals such as rubidium, cesium and francium could also be made into Boroncitrates; but, there is no advantage in using these very scarce and much more expensive alkali metals. Use of Boroncitrates provides a new and improved means for hydraulic cementitious compositions to take set faster or slower, as determined by the user and as the individual jobsite needs dictate; thereby providing the long-sought, unfulfilled flexibility required by today's rapidly expanding concrete industry.

Abstract: Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic agents in the treatment of cancer.

Abstract: Boroncitrates provide a new and improved means for hydraulic cement compositions to take set faster or slower, as determined by the user and as the individual jobsite needs dictate; thereby providing the flexibility required in the concrete industry. Boroncitrates include boron lithium citrate, boron potassium citrate, and boron sodium citrate which may be used alone or in mixtures thereof. They can be used in but not limited to Portland cement, Class C Fly Ash, blended hydraulic cements, and mixtures thereof.

Abstract: A deheader valve is fitted onto an existing or new coke drum by initially positioning the body and valve, and then raising the valve to mate with the flange using a lifting device other than a chain fall. The vertical positioning of the deheader valve is preferably accomplished with a hydraulic or pneumatic piston, winch, scissor jack, ratchet jack, screw jack, and so forth. The distance traveled by the valve using these devices is more than 2 cm, commonly at least 20 cm, and in some installations up to 40 cm or more. In retrofit situations an oil inlet is provided in a side wall of the drum above the bottom drum flange.

Abstract: A system (10) and method for monitoring the operational life and/or performance of one or more light-emitting diodes (LEDs) (20) based on sensed parameters are disclosed. The remaining life of each LED may be predicted by counting the clock cycles during which the LED-based light is activated. LED current and/or temperature measurements may be used to control the clock signal and, thus, to compensate the predicted life value. Furthermore, operational characteristics of the LED-based light may be monitored based on LED current and/or voltage measurements. Such characteristics may include performance (e.g., intensity) and failure conditions (e.g., open or short circuits).

Abstract: A cover for a rotary die is centrifugally cast with multiple layers to substantially eliminate stress when the cover is cast in an arcuate shape for use in a die cutting system. A locking mechanism attached to ends of the cover is designed to be convenient to install on and remove from a cutting cylinder.

Abstract: A cover for a rotary die is centrifugally cast with multiple layers to substantially eliminate stress when the cover is cast in an arcuate shape for use in a die cutting system. A locking mechanism attached to ends of the cover is designed to be convenient to install on and remove from a cutting cylinder.