Abstract: Disclosed herein are microelectronics package architectures utilizing photo-integrated glass interposers and photonic integrated glass layers and methods of manufacturing the same. The microelectronics packages may include an organic substrate, a photonic integrated glass layer, and a glass interpose. The organic substrate may define through substrate vias. The photonic integrated glass layer may be attached to the organic substrate. The photonic integrated glass layer may include photo detectors. The glass interposer may be attached to the organic substrate. The glass interposer may define through glass vias in optical communication with the photo detectors.

Abstract: Embodiments of the disclosure include methods and systems for attaching an articulation section. In an embodiment, a medical instrument includes a first tubular member including a first end. The medical instrument also includes a second tubular member including a first end. The second tubular member includes a plurality of layers including an inner layer and a first layer including a fluorinated material. The inner layer includes a first section disposed under the first layer and a second section extending out from under the first layer. A portion of the first tubular member overlaps and is bonded to at least a portion of the second section of the inner layer of the second tubular member.

Abstract: A build plate includes a surface that defines at least one opening configured for disposal of a proximal portion of a screw shaft. The proximal portion is formed by a first manufacturing method and defines a distal face. The proximal portion is connected with the surface in a configuration to orient the distal face for forming a distal portion of the screw shaft thereon by a second manufacturing method that includes an additive manufacturing apparatus. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: A bone fastener includes a screw shaft having a proximal portion and a distal portion. The proximal portion is formed by a first manufacturing method and defines a distal face. The distal portion is formed onto the distal face by a second manufacturing method. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Compositions and methods of identifying and characterizing potential gene editing on-target and off-target sites and/or edits in a nucleic acid are provided.

Abstract: A bone fastener includes a screw shaft having a proximal portion and a distal portion. The proximal portion is formed by a first manufacturing method and defines a distal face. The distal portion is formed onto the distal face by a second manufacturing method. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: A build-plate with integrally-formed spinal implant constructs and a method used in forming spinal implant constructs on the build-plate and machining the spinal implant constructs formed on the build-plate to manufacture spinal implants is provided. The spinal implant constructs can be formed via additive manufacturing processes by adding material to an upper surface of the build-plate, and then the spinal implant constructs can be subjected to subtractive manufacturing processes to form the spinal implants.

Abstract: Compositions and methods of identifying and characterizing potential gene editing on-target and off-target sites and/or edits in a nucleic acid are provided.

Abstract: A build-plate with integrally-formed spinal implant constructs and a method used in forming spinal implant constructs on the build-plate and machining the spinal implant constructs formed on the build-plate to manufacture spinal implants is provided. The spinal implant constructs can be formed via additive manufacturing processes by adding material to an upper surface of the build-plate, and then the spinal implant constructs can be subjected to subtractive manufacturing processes to form the spinal implants.

Abstract: An interlocking tailgate utility bar for a vehicle having a tailgate at least partially defining a cargo area includes a top surface, a bottom surface opposite the top surface and configured to be disposed against an inner wall of the tailgate when the tailgate is in an open position, opposed front and rear side surfaces, and opposed ends. A striker assembly is disposed at each end of the opposed ends and includes a striker configured to be releasably coupled to tailgate latches located on opposed sides of the tailgate to thereby selectively releasably secure the interlocking tailgate utility bar to the tailgate. A rail channel is configured to receive an attachment device of a vehicle accessory to thereby removably couple the vehicle accessory to the interlocking tailgate utility bar and thus the vehicle.

Abstract: A build plate includes a surface that defines at least one opening configured for disposal of a proximal portion of a screw shaft. The proximal portion is formed by a first manufacturing method and defines a distal face. The proximal portion is connected with the surface in a configuration to orient the distal face for forming a distal portion of the screw shaft thereon by a second manufacturing method that includes an additive manufacturing apparatus. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: A build plate includes a surface that defines at least one opening configured for disposal of a proximal portion of a screw shaft. The proximal portion is formed by a first manufacturing method and defines a distal face. The proximal portion is connected with the surface in a configuration to orient the distal face for forming a distal portion of the screw shaft thereon by a second manufacturing method that includes an additive manufacturing apparatus. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Multi-driver configuration apparatuses, systems, and methods are provided. Apparatuses, systems, and methods are provided for multi-driver configuration of a plurality of light emitting diode (LED) drivers. The system includes a plurality of LED drivers having a transformer, an input interface coupleable to the configuration device via a common communication medium, a microcontroller, a direct current (DC) sensing section to detect at least a portion of a tuning signal received at the input interface and to transmit a driver control input signal corresponding to the at least a portion of the tuning signal to the microcontroller, and a transmit switch configured to receive a driver control output signal from the microcontroller and to cause at least one output signal to be output from the LED driver via the input interface. A configuration device transmits the tuning signal to at least one LED driver.

Abstract: A bone fastener includes a screw shaft having a proximal portion and a distal portion. The proximal portion is formed by a first manufacturing method and defines a distal face. The distal portion is formed onto the distal face by a second manufacturing method. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Systems and methods for improving marker-trait associations and for improving trait introgression precision while reducing trait introgression time are disclosed. Genes responsible for recombination are edited to reduce function, and thus increase recombination rates. Increased recombination rates allow more precise quantification of marker-trait associations, and more precise and faster trait introgression. Methods and compositions useful for selecting an organism with a trait of interest are provided herein. Candidate organisms identified and/or selected by any of the methods described above are also of interest.

Abstract: A build-plate with integrally-formed spinal implant constructs and a method used in forming spinal implant constructs on the build-plate and machining the spinal implant constructs formed on the build-plate to manufacture spinal implants is provided. The spinal implant constructs can be formed via additive manufacturing processes by adding material to an upper surface of the build-plate, and then the spinal implant constructs can be subjected to subtractive manufacturing processes to form the spinal implants.

Abstract: A bone fastener includes a screw shaft having a proximal portion and a distal portion. The proximal portion is formed by a first manufacturing method and defines a distal face. The distal portion is formed onto the distal face by a second manufacturing method. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: An interlocking tailgate utility bar for a vehicle having a tailgate at least partially defining a cargo area includes a top surface, a bottom surface opposite the top surface and configured to be disposed against an inner wall of the tailgate when the tailgate is in an open position, opposed front and rear side surfaces, and opposed ends. A striker assembly is disposed at each end of the opposed ends and includes a striker configured to be releasably coupled to tailgate latches located on opposed sides of the tailgate to thereby selectively releasably secure the interlocking tailgate utility bar to the tailgate. A rail channel is configured to receive an attachment device of a vehicle accessory to thereby removably couple the vehicle accessory to the interlocking tailgate utility bar and thus the vehicle.

Abstract: A method for determining geo-position of a target by an aircraft includes: receiving navigation data related to the aircraft including aircraft attitude information; receiving multilateration information related to the target including an angle to the target; calculating an axis for a cone fixed to the aircraft, based on the received aircraft attitude information; calculating a central angle for the cone from the received angle to the target; generating two vectors orthogonal to the cone axis; calculating a cone model from the axis, the central angle and the two vectors; and intersecting the cone model with an earth model to obtain a LEP curve, wherein the LEP curve is used to determine the geo position of the target.

Abstract: A portable apparatus is provided for configuring and/or programming lighting drivers without mains power application. An apparatus housing comprises first and second connectors and an antenna. During a first mode wherein the first connector is coupled to an external computing device, a battery receives and stores power therefrom, and a first controller receives and stores at least driver configuration settings therefrom. When the external device is disconnected the battery powers the apparatus, which polls a transceiver circuit to detect a driver antenna proximate to the apparatus antenna. The apparatus housing is configured to mount to a luminaire comprising the detected driver, wherein the second connector is coupled to the driver and the battery provides power to a driver controller. The first controller also during this second mode transfers the stored at least driver configuration settings to the driver controller via the operably proximate antennae, for example via bidirectional negotiations therewith.