Abstract: A holding device for fastening bar cutters in order for the cutting edges thereof to be coated, wherein the fastening is configured in such a way that a plurality of bar cutters can be arranged in a row such that the cutting faces and tips thereof have the same orientation, and the holding device includes a screen which at least partially protects the cutting faces from the coating, wherein, with bar cutters arranged in a row in the manner described, the top edge of the screen projects beyond the knife tips in such a way that no knife tips protrude.

Abstract: A holding device for fastening bar cutters in order for the cutting edges thereof to be coated, wherein the fastening is configured in such a way that a plurality of bar cutters can be arranged in a row such that the cutting faces and tips thereof have the same orientation, and the holding device includes a screen which at least partially protects the cutting faces from the coating, wherein, with bar cutters arranged in a row in the manner described, the top edge of the screen projects beyond the knife tips in such a way that no knife tips protrude.

Abstract: This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.

Abstract: An isolated mineralocorticoid receptor (MR) polypeptide, or functional portion thereof, having one or more mutations that alter the solubility or crystal-forming properties and confer the ability to generate soluble protein complexes with the MR and ligands that only weakly bind the native polypeptide, and a polynucleotide encoding it are disclosed. Representative mutations are C808S and S810L substitutions. Expression of the MR polypeptide in E. coli is also provided. A solved three-dimensional crystal structure of an MR ligand binding domain polypeptide is also disclosed, along with a crystalline form of the MR ligand binding domain polypeptide.

Abstract: This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.

Abstract: A solved three-dimensional crystal structure of a glucocorticord receptor (GR) ? ligand binding domain polypeptide is disclosed, in the form of a crystalline glucocorticord receptor ? ligand binding domain polypeptide in complex with the ligand fluticasone propionate (FP) and a peptide derived from the co-activator TIF2. The GR/FP/TIF2 structure includes an expanded binding pocket not seen in other GR structures. Methods of designing steroid and non-steroid modulators of the biological activity of GR and other nuclear receptors (NRs) are also disclosed. In another aspect of the present invention homology models of androgen receptor (AR), progesterone receptor (PR) and mineralcorticoid receptor (MR) are disclosed, as well as methods of forming homology models for other NRs. Methods of forming a soluble GR/FP/TIF2 complex are also disclosed.

Abstract: This invention relates to non-steroidal compounds that are or are believed to be modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.

Abstract: This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.

Abstract: The invention relates to methods for the treatment or prevention of an LXR mediated disease or condition, including cardiovascular disease and atherosclerosis, novel compounds for use in such methods and pharmaceutical compositions comprising compounds for use in such methods.

Abstract: The invention relates to a compound of formula (I), wherein all variables are as defined herein, and pharmaceutically acceptable salts or solvates thereof. The compounds of formula (I) are useful as LXR agonists.

Abstract: In accordance with the present invention, a method and apparatus is provided for maintaining the coherency of victim data from a time when the data is stored in a victim data buffer until a time when the data is written into a main memory. Alternatively, the coherency of the victim data is preserved until a determination is made that pending probe messages do not target the victim data. At that time the victim data buffer can be deallocated.With both arrangements, a central processing unit can release a victim data buffer at a point in time other than when the data that is stored therein is read from the buffer. Thus, the central processor unit can perform the release or deallocation of the buffer when it is most efficient and when no further access to the data is required.

Abstract: In accordance with the present invention, a method and apparatus is provided for storing victim data evicted from a cache and for satisfying pending requests or probe messages that target victim data, using a set of victim data buffers coupled to a central processing unit of a computer system. Storage locations referred to as a "victim valid bit" and a "probe valid bit" are associated with each victim data buffer in the computer system to indicate a release condition for the coupled victim data buffer. With such an arrangement, the victim data buffer can be deallocated when the victim valid bit and the probe valid bit have both been cleared.

Abstract: An active matrix liquid crystal display (AMLCD) and driving method is disclosed. The AMLCD has matrix-arranged pixel assemblies each having display electrodes. A gate line for carrying gate line pulses is connected to a control port of a row of semiconductor devices, which may be thin film transistors (TFTs). Each TFT has an output port connected to the display electrodes. In addition, a data line is connected to an input port of a column of the TFTs. A bootstrap line is capacitively connected to the display electrodes of adjacent rows. This reduce the number of bootstrap lines to half the number of gate and data lines. A bootstrap pulse timing and generating circuit is connected to the bootstrap line to provide a bootstrap pulse that shifts voltages on the display electrodes in only one direction. The bootstrap pulse has a first edge of a first polarity occurring before or during gate pulses carried on a gate line, and a second edge of a second polarity occurring after the gate line pulses.

Abstract: A compact and short tampon applicator is formed of an outer barrel which surrounds a tampon-holding inner tubular plunger which is slidable within the outer barrel. A portion of the wall of the plunger defines a pair of hinged panels which snap into the interior of the plunger in response to an inwardly directed radial force. This inward force is supplied by a tab on the barrel, once the plunger has been retracted sufficiently out of the barrel to register the hinged panels with the tab. The applicator is readied for use by retracting the plunger rearwardly behind the tampon, sufficiently to cause the hinged panels to engage the tab on the inner surface of the barrel to snap into the plunger. After insertion of the barrel into the catamenial canal, the plunger is pressed inward, back into the barrel, to enable its inwardly snapped panels to engage the rear of the tampon and to eject the tampon through the front of the barrel.

Abstract: A fare computer for a taxi, a freight carrier, or other use calculates the fare, display the fare as it accrues and displays visual representations of each charge contributing to the accrued fare. The fare computer is particularly suited for use in those localitites in which the taxi fare is based upon zones of travel, in accordance with a zone tariff schedule, rather than on total distance travelled. In a first mode, or ZONE TARIFF MODE, the fare computer calculates the fare from primary charge data, derived from the number of zones traversed in travelling from the origin of the trip to the destination, and secondary charge data, derived from such events as the handling of luggage or pets, extra stops, extra passengers or responding to a telephone request for passenger pick up. A display presents visual representations of the origin and destination zones and of each secondary charge contributing to the accrued fare, along with display of the total accrued fare.

Abstract: A light pen detection and tracking scheme for detecting and tracking both "on" and "off" cells with a single cursor voltage waveform in an AC gas discharge display panel. The special cursor voltage waveform is applied to the panel during the sustain cycle, in either a line-by-line or binary scanning fashion, to momentarily fire both "on" and "off" cells so that they may be detected by the light pen without a loss of the memory state of the cells. A cross-hair cursor is automatically displayed at the pen position when the search scan is complete. Since both "on" and "off" cells are detected, the system can respond to pen motion by repeating the search to reacquire the pen, so that no special tracking strategy is needed.

Abstract: Improved writing and erasing in AC gas discharge display panels is obtained by applying a special normalizing voltage waveform to cause the cells to be in a more standardized state, so that the applied writing and erasing pulses act to cause wall voltage changes which are less sensitive to the cell's recent history. The special normalizing waveform is applied adjacent to the erase pulse and/or to the write pulse and acts to fire the cells in a manner such that there is no loss in the memory state of the cells.

Abstract: A nondestructive, transparent cursor for AC plasma displays may be superimposed electronically over a displayed image without regenerating the original image each time the cursor is moved. The cursor is displayed by means of a special cursor drive waveform which discharges both previously "on" and "off" cells which form the cursor but permits reversion of the cells to their original state when the cursor drive waveform is removed and the normal sustaining waveform is restored.

Abstract: A distributed Josephson junction logic circuit is disclosed which includes a plurality of serially disposed Josephson junctions in a superconductive wire-over-groundplane environment wherein the latter is terminated at both ends in its characteristic impedance and energized at one end with a constant voltage source. In addition, at least one portion of the wire-over-groundplane transmission line, which is disposed in series with the junctions, is utilized as an output control and has the same steady state current flowing in it as the plurality of Josephson junctions. Utilizing such an arrangement, logic can be performed by means of multiple controls on a single junction as in terminated line logic or by means of several junctions, each with one or more independent controls, in series. The design is such that the switching of any one or more junctions to the voltage state causes a decrease in current from a level which represents a logical "1" to a lesser current which is representative of a logical "0".

Abstract: An endless woven garniture tape or belt for cigarette making machines comprising a combination of natural, chemically modified, and synthetic fibers in a unique blend and arrangement which possesses properties that result in superior wear life performance without sacrificing other performance criteria. The warp is made from combed sak cotton fiber threads, with a multiplicity of such threads mercerized and plied together to form each warp thread. The filling threads are made up of a multifilament synthetic core wrapped with cotton fiber with a multiplicity of such wrapped threads plied together to form each filling thread. Endless belts made according to this invention have a wear life approximating three times the normal wear life of conventional belts used on cigarette making machines.